S0125, Chemotherapy, Total-Body Irradiation, and Peripheral Stem Cell Transplantation in Treating Older Patients With Acute Myeloid Leukemia
Public ClinicalTrials.gov record NCT00053014. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.
Official title
S0125, A Phase II Study Of Chimerism-Mediated Immunotherapy (CMI) Using Nonmyeloablative Allogeneic Peripheral Blood Stem Cell Transplantation In Older Patients With Acute Myeloid Leukemia (AML) In First Complete Remission (A BMT Study)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Peripheral stem cell transplantation may be able to replace immune cells that were destroyed by chemotherapy and radiation therapy. Sometimes the transplanted cells can make an immune response against the body's normal tissues. Cyclosporine and mycophenolate mofetil may prevent this from happening. PURPOSE: Phase II trial to study the effectiveness of chemotherapy and total-body irradiation followed by donor peripheral stem cell transplantation, cyclosporine, and mycophenolate mofetil in treating older patients who have acute myeloid leukemia.
Study identification
- NCT ID
- NCT00053014
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 5 participants
Conditions and interventions
Conditions
Interventions
- therapeutic allogeneic lymphocytes Biological
- cyclosporine Drug
- fludarabine Drug
- mycophenolate mofetil Drug
- peripheral blood stem cell transplantation Procedure
- radiation therapy Radiation
Biological · Drug · Procedure + 1 more
Eligibility (public fields only)
- Age range
- 55 Years to 69 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 2003 (Type not available)
- Primary completion
- Jun 2005 (Actual)
- Completion
- Jun 2006 (Actual)
- Last update posted
- Mar 25, 2015
2003 – 2006
United States locations
- U.S. sites
- 83
- U.S. states
- 28
- U.S. cities
- 58
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Banner Good Samaritan Medical Center | Phoenix | Arizona | 85006 | — |
| Veterans Affairs Medical Center - Tucson | Tucson | Arizona | 85723 | — |
| Arizona Cancer Center at University of Arizona Health Sciences Center | Tucson | Arizona | 85724 | — |
| Arkansas Cancer Research Center at University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| Veterans Affairs Medical Center - Little Rock | Little Rock | Arkansas | 72205 | — |
| City of Hope Comprehensive Cancer Center | Duarte | California | 91010-3000 | — |
| Scripps Cancer Center at Scripps Clinic | La Jolla | California | 92037-1027 | — |
| USC/Norris Comprehensive Cancer Center and Hospital | Los Angeles | California | 90033 | — |
| Jonsson Comprehensive Cancer Center at UCLA | Los Angeles | California | 90095-1678 | — |
| Veterans Affairs Outpatient Clinic - Martinez | Martinez | California | 94553 | — |
| Chao Family Comprehensive Cancer Center at University of California Irvine Medical Center | Orange | California | 92868 | — |
| Sutter Cancer Center | Sacramento | California | 95816 | — |
| University of California Davis Cancer Center | Sacramento | California | 95817 | — |
| Stanford Cancer Center at Stanford University Medical Center | Stanford | California | 94305-5408 | — |
| General Robert Huyser Cancer Center at David Grant Medical Center | Travis Air Force Base | California | 94535 | — |
| John Muir/Mt. Diablo Comprehensive Cancer Center | Walnut Creek | California | 94598 | — |
| University of Colorado Cancer Center at University of Colorado Health Sciences Center | Aurora | Colorado | 80010 | — |
| Veterans Affairs Medical Center - Denver | Denver | Colorado | 80220 | — |
| Veterans Affairs Medical Center - Tampa (Haley) | Tampa | Florida | 33612 | — |
| CCOP - Atlanta Regional | Atlanta | Georgia | 30342-1701 | — |
| Charles B. Eberhart Cancer Center at DeKalb Medical Center | Decatur | Georgia | 30033 | — |
| Dwight David Eisenhower Army Medical Center | Fort Gordon | Georgia | 30905-5650 | — |
| Cancer Research Center of Hawaii | Honolulu | Hawaii | 96813 | — |
| MBCCOP - Hawaii | Honolulu | Hawaii | 96813 | — |
| Mountain States Tumor Institute - Boise | Boise | Idaho | 83712 | — |
| Veterans Affairs Medical Center - Chicago Westside Hospital | Chicago | Illinois | 60612 | — |
| Veterans Affairs Medical Center - Hines | Hines | Illinois | 60141 | — |
| Cardinal Bernardin Cancer Center at Loyola University Medical Center | Maywood | Illinois | 60153-5500 | — |
| Indiana Blood and Marrow Transplantation | Beech Grove | Indiana | 46107 | — |
| Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center | Kansas City | Kansas | 66160-7353 | — |
| CCOP - Wichita | Wichita | Kansas | 67214-3882 | — |
| Veterans Affairs Medical Center - Wichita | Wichita | Kansas | 67218 | — |
| Veterans Affairs Medical Center - Lexington | Lexington | Kentucky | 40502-2236 | — |
| Markey Cancer Center at University of Kentucky Chandler Medical Center | Lexington | Kentucky | 40536-0084 | — |
| MBCCOP - LSU Health Sciences Center | New Orleans | Louisiana | 70112 | — |
| Tulane Cancer Center at Tulane University Hospital and Clinic | New Orleans | Louisiana | 70112 | — |
| Veterans Affairs Medical Center - New Orleans | New Orleans | Louisiana | 70112 | — |
| New Orleans Cancer Institute at Memorial Medical Center | New Orleans | Louisiana | 70115 | — |
| Veterans Affairs Medical Center - Shreveport | Shreveport | Louisiana | 71101-4295 | — |
| Feist-Weiller Cancer Center at Louisiana State University Health Sciences | Shreveport | Louisiana | 71130-3932 | — |
| Massachusetts General Hospital Cancer Center | Boston | Massachusetts | 02114 | — |
| Cancer Research Center at Boston Medical Center | Boston | Massachusetts | 02118 | — |
| University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | 48109-0948 | — |
| Barbara Ann Karmanos Cancer Institute | Detroit | Michigan | 48201-1379 | — |
| Veterans Affairs Medical Center - Detroit | Detroit | Michigan | 48201-1932 | — |
| Josephine Ford Cancer Center at Henry Ford Health System | Detroit | Michigan | 48202 | — |
| Providence Cancer Institute at Providence Hospital - Southfield Campus | Southfield | Michigan | 48075 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216-4505 | — |
| Veterans Affairs Medical Center - Jackson | Jackson | Mississippi | 39216 | — |
| CCOP - Kansas City | Kansas City | Missouri | 64131 | — |
| Saint Louis University Cancer Center | St Louis | Missouri | 63110 | — |
| CCOP - Montana Cancer Consortium | Billings | Montana | 59101 | — |
| Veterans Affairs Medical Center - Albuquerque | Albuquerque | New Mexico | 87108-5138 | — |
| Veterans Affairs Medical Center - Albany | Albany | New York | 12208 | — |
| NYU Cancer Institute at New York University Medical Center | New York | New York | 10016 | — |
| Herbert Irving Comprehensive Cancer Center at Columbia University | New York | New York | 10032 | — |
| James P. Wilmot Cancer Center at University of Rochester Medical Center | Rochester | New York | 14642 | — |
| Veterans Affairs Medical Center - Cincinnati | Cincinnati | Ohio | 45220-2288 | — |
| Cleveland Clinic Taussig Cancer Center | Cleveland | Ohio | 44195-9001 | — |
| Veterans Affairs Medical Center - Dayton | Dayton | Ohio | 45428-1002 | — |
| CCOP - Dayton | Dayton | Ohio | 45429 | — |
| Oklahoma University Medical Center | Oklahoma City | Oklahoma | 73104 | — |
| Veterans Affairs Medical Center - Oklahoma City | Oklahoma City | Oklahoma | 73104 | — |
| Cancer Institute at Oregon Health and Science University | Portland | Oregon | 97201-3098 | — |
| CCOP - Columbia River Oncology Program | Portland | Oregon | 97225 | — |
| Veterans Affairs Medical Center - Charleston | Charleston | South Carolina | 29401-5799 | — |
| CCOP - Greenville | Greenville | South Carolina | 29615 | — |
| University of Tennessee Cancer Institute at Methodist Central Hospital | Memphis | Tennessee | 38104 | — |
| Veterans Affairs Medical Center - Amarillo | Amarillo | Texas | 79106 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| Wilford Hall Medical Center | Lackland Air Force Base | Texas | 78236-5300 | — |
| UMC Southwest Cancer and Research Center | Lubbock | Texas | 79415-3364 | — |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78229-3900 | — |
| Veterans Affairs Medical Center - San Antonio (Murphy) | San Antonio | Texas | 78229 | — |
| Veterans Affairs Medical Center - Temple | Temple | Texas | 76504 | — |
| Huntsman Cancer Institute at University of Utah | Salt Lake City | Utah | 84132 | — |
| Veterans Affairs Medical Center - Salt Lake City | Salt Lake City | Utah | 84148 | — |
| CCOP - Virginia Mason Research Center | Seattle | Washington | 98101 | — |
| Swedish Cancer Institute at Swedish Medical Center - First Hill Campus | Seattle | Washington | 98104 | — |
| Veterans Affairs Medical Center - Seattle | Seattle | Washington | 98108 | — |
| Fred Hutchinson Cancer Research Center | Seattle | Washington | 98109-1024 | — |
| CCOP - Northwest | Tacoma | Washington | 98405-0986 | — |
| Madigan Army Medical Center | Tacoma | Washington | 98431-5000 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00053014, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 25, 2015 · Synced Nov 6, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00053014 live on ClinicalTrials.gov.