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Completed Phase 3 Interventional

Study of Neurologic Progression With Motexafin Gadolinium and Radiation Therapy (SMART)

ClinicalTrials.gov ID: NCT00054795

Public ClinicalTrials.gov record NCT00054795. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 26, 2026, 4:51 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Randomized Phase III Trial of Xcytrin® (Motexafin Gadolinium) Injection for the Treatment of Brain Metastases in Patients With Non-Small Cell Lung Cancer Undergoing Whole Brain Radiation Therapy

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The primary purpose of the study is to determine if patients with brain metastases from non-small cell lung cancer treated with Motexafin Gadolinium and whole brain radiation therapy retain their neurologic function and ability to think for a longer time compared to patients treated with whole brain radiation therapy alone.

Study identification

NCT ID
NCT00054795
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Pharmacyclics LLC.
Industry
Enrollment
550 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Not listed
Primary completion
Not listed
Completion
Not listed
Last update posted
May 8, 2007

United States locations

U.S. sites
44
U.S. states
23
U.S. cities
44
Facility City State ZIP Site status
Not listed Phoenix Arizona — —
Not listed Fort Smith Arkansas — —
Not listed Little Rock Arkansas — —
Not listed Berkeley California — —
Not listed Concord California — —
Not listed Greenbrae California — —
Not listed Los Angeles California — —
Not listed Montebello California — —
Not listed Sacramento California — —
Not listed Stanford California — —
Not listed Aurora Colorado — —
Not listed Hartford Connecticut — —
Not listed New Haven Connecticut — —
Not listed Chicago Illinois — —
Not listed Fort Wayne Indiana — —
Not listed Indianapolis Indiana — —
Not listed Shreveport Louisiana — —
Not listed Baltimore Maryland — —
Not listed Washington D.C Maryland — —
Not listed Boston Massachusetts — —
Not listed Detroit Michigan — —
Not listed Grand Rapids Michigan — —
Not listed Minneapolis Minnesota — —
Not listed St Louis Missouri — —
Not listed Omaha Nebraska — —
Not listed Camden New Jersey — —
Not listed Morristown New Jersey — —
Not listed Albuquerque New Mexico — —
Not listed New York New York — —
Not listed Rochester New York — —
Not listed Akron Ohio — —
Not listed Cleveland Ohio — —
Not listed Columbus Ohio — —
Not listed Hershey Pennsylvania — —
Not listed Philadelphia Pennsylvania — —
Not listed Knoxville Tennessee — —
Not listed Nashville Tennessee — —
Not listed Houston Texas — —
Not listed Laredo Texas — —
Not listed San Antonio Texas — —
Not listed Tyler Texas — —
Not listed Charlottesville Virginia — —
Not listed Madison Wisconsin — —
Not listed Milwaukee Wisconsin — —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 48 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00054795, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 8, 2007 · Synced Oct 26, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00054795 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →