Study of HGF Via Plasmid Vector to Improve Perfusion in Critical Limb Ischemia
Public ClinicalTrials.gov record NCT00060892. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II Double-Blind, Randomized, Placebo-Controlled Study to Assess the Safety and Efficacy of AMG0001 to Improve Perfusion in Critical Leg Ischemia
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary purpose of this study was to assess the overall safety of different dose regimens of AMG0001 (HGF transferred via plasmid vector) as well as evaluate the improvement of blood perfusion in subjects with critical limb ischemia (CLI). This study also evaluated the improvement in wound healing without adverse effects on the quality of life, as well as the potential reduction of amputation, mortality and rest pain in the CLI population.
Study identification
- NCT ID
- NCT00060892
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 104 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 40 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 2003 (Type not available)
- Primary completion
- May 2006 (Actual)
- Completion
- Jan 2007 (Actual)
- Last update posted
- Jan 11, 2008
2003 – 2007
United States locations
- U.S. sites
- 24
- U.S. states
- 16
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cardiology, P.C. | Birmingham | Alabama | 35211 | — |
| Central Arkansas Veteran's Healthcare System | Little Rock | Arkansas | 72205 | — |
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| Falk Cardiovascular Research Center | Stanford | California | 94305 | — |
| VA Medical Center Surgical Service (112) | Washington D.C. | District of Columbia | 20422 | — |
| Basptist Hospital | Pensacola | Florida | 32501 | — |
| University of South Florida College of Medicine | Tampa | Florida | 33606 | — |
| American Cardiovascular Research Institute | Atlanta | Georgia | 30342 | — |
| University of Chicago Hospitals | Chicago | Illinois | 60637 | — |
| The Care Group, LLC | Indianapolis | Indiana | 46290 | — |
| The Ochsner Heart and Vascular Institute | Metairie | Louisiana | 70002 | — |
| Minneapolis Heart Institute Foundation | Minneapolis | Minnesota | 55407 | — |
| Dartmouth - Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| Diabetes Foot and Ankle Center | New York | New York | 10003 | — |
| NYPH-NY Weill Cornell Medical Center | New York | New York | 10021 | — |
| University of Rochester | Rochester | New York | 14642 | — |
| Pitt County Memorial Hospital | Greenville | North Carolina | 27834 | — |
| The Lindner Clinical Trial Center | Cincinnati | Ohio | 45219 | — |
| The Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Jobst Vascular Center | Toledo | Ohio | 43606 | — |
| Medical College of Ohio | Toledo | Ohio | 43614 | — |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| Peripheral Vascular Associates | San Antonio | Texas | 78215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00060892, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 11, 2008 · Synced Oct 24, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00060892 live on ClinicalTrials.gov.