Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Treatment
Public ClinicalTrials.gov record NCT00066248. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
The Effect of Cyproheptadine Hydrochloride (Periactin) and Megestrol Acetate (Megace) on Weight in Children With Cancer/Treatment Related Cachexia
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Cyproheptadine and megestrol may improve appetite and help prevent weight loss in children with cancer. PURPOSE: This phase II trial is studying how well cyproheptadine and megestrol work in improving appetite and preventing weight loss in children with cachexia caused by cancer or cancer treatment.
Study identification
- NCT ID
- NCT00066248
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 70 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 2 Years to 20 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 2003 (Type not available)
- Primary completion
- Aug 2007 (Actual)
- Completion
- Aug 2007 (Actual)
- Last update posted
- Feb 3, 2014
2003 – 2007
United States locations
- U.S. sites
- 40
- U.S. states
- 22
- U.S. cities
- 36
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| CCOP - Bay Area Tumor Institute | Oakland | California | 94609-3305 | — |
| Children's Hospital & Research Center Oakland | Oakland | California | 94609 | — |
| Children's National Medical Center | Washington D.C. | District of Columbia | 20010-2970 | — |
| University of Florida Shands Cancer Center | Gainesville | Florida | 32610-0296 | — |
| Nemours Children's Clinic | Jacksonville | Florida | 32207 | — |
| Sacred Heart Cancer Center at Sacred Heart Hospital | Pensacola | Florida | 32504 | — |
| All Children's Hospital | St. Petersburg | Florida | 33701 | — |
| St. Joseph's Children's Hospital of Tampa | Tampa | Florida | 33677-4227 | — |
| CCOP - Florida Pediatric | Tampa | Florida | 33682-7757 | — |
| Kaplan Cancer Center at St. Mary's Medical Center | West Palm Beach | Florida | 33407 | — |
| MBCCOP - Medical College of Georgia Cancer Center | Augusta | Georgia | 30912-4000 | — |
| Cancer Research Center of Hawaii | Honolulu | Hawaii | 96813 | — |
| Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center | Kansas City | Kansas | 66160-7357 | — |
| Children's Hospital of New Orleans | New Orleans | Louisiana | 70118 | — |
| Floating Hospital for Children at Tufts - New England Medical Center | Boston | Massachusetts | 02111 | — |
| Van Elslander Cancer Center at St. John Hospital and Medical Center | Detroit | Michigan | 48236 | — |
| DeVos Children's Hospital | Grand Rapids | Michigan | 49503 | — |
| CCOP - Beaumont | Royal Oak | Michigan | 48073-6769 | — |
| University of Minnesota Cancer Center | Minneapolis | Minnesota | 55455 | — |
| Children's Hospitals and Clinics of Minnesota - Minneapolis | Saint Paul | Minnesota | 55106-2049 | — |
| Siteman Cancer Center at Barnes-Jewish Hospital | St Louis | Missouri | 63110 | — |
| Tomorrows Children's Institute at Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263-0001 | — |
| SUNY Upstate Medical University Hospital | Syracuse | New York | 13210 | — |
| Blumenthal Cancer Center at Carolinas Medical Center | Charlotte | North Carolina | 28232-2861 | — |
| Wake Forest University Comprehensive Cancer Center | Winston-Salem | North Carolina | 27157-1096 | — |
| Children's Hospital Medical Center of Akron | Akron | Ohio | 44308-1062 | — |
| Columbus Children's Hospital | Columbus | Ohio | 43205-2696 | — |
| Children's Medical Center - Dayton | Dayton | Ohio | 45404-1815 | — |
| Tod Children's Hospital | Youngstown | Ohio | 44501 | — |
| Legacy Emanuel Hospital and Health Center & Children's Hospital | Portland | Oregon | 97227 | — |
| Children's Hospital of Pittsburgh | Pittsburgh | Pennsylvania | 15213 | — |
| CHRISTUS Santa Rosa Children's Hospital | San Antonio | Texas | 78207 | — |
| MBCCOP - South Texas Pediatrics | San Antonio | Texas | 78229-3900 | — |
| Methodist Cancer Center at Methodist Specialty and Transplant Hospital | San Antonio | Texas | 78229-3902 | — |
| CCOP - Scott and White Hospital | Temple | Texas | 76508 | — |
| Vermont Cancer Center at University of Vermont | Burlington | Vermont | 05405-0110 | — |
| Virginia Commonwealth University Massey Cancer Center | Richmond | Virginia | 23298-0121 | — |
| Children's Hospital and Regional Medical Center - Seattle | Seattle | Washington | 98105-3916 | — |
| St. Vincent Hospital Regional Cancer Center | Green Bay | Wisconsin | 54307-9070 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00066248, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 3, 2014 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00066248 live on ClinicalTrials.gov.