Tacrolimus and Mycophenolate Mofetil With or Without Sirolimus in Preventing Acute Graft-Versus-Host Disease in Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer
Public ClinicalTrials.gov record NCT00105001. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized Phase II Study to Determine the Most Promising Postgrafting Immunosuppression for Prevention of Acute GVHD After Unrelated Donor G-CSF Mobilized Peripheral Blood Mononuclear Cell (G-PBMC) Transplantation Using Nonmyeloablative Conditioning for Patients With Hematologic Malignancies A Multi-Center Trial
Study identification
- NCT ID
- NCT00105001
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Fred Hutchinson Cancer Center
- Other
- Enrollment
- 210 participants
Conditions and interventions
Conditions
- Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive
- Adult Acute Lymphoblastic Leukemia in Remission
- Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11
- Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); RUNX1-RUNX1T1
- Adult Acute Myeloid Leukemia With t(9;11)(p22;q23); MLLT3-MLL
- Adult Acute Myeloid Leukemia in Remission
- Adult Acute Promyelocytic Leukemia With t(15;17)(q22;q12); PML-RARA
- Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative
- Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive
- Childhood Acute Lymphoblastic Leukemia in Remission
- Childhood Acute Myeloid Leukemia in Remission
- Childhood Burkitt Lymphoma
- Childhood Chronic Myelogenous Leukemia, BCR-ABL1 Positive
- Childhood Diffuse Large Cell Lymphoma
- Childhood Immunoblastic Lymphoma
- Childhood Myelodysplastic Syndrome
- Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable
- Previously Treated Myelodysplastic Syndrome
- Recurrent Adult Acute Lymphoblastic Leukemia
- Recurrent Adult Acute Myeloid Leukemia
- Recurrent Adult Burkitt Lymphoma
- Recurrent Adult Diffuse Large Cell Lymphoma
- Recurrent Adult Diffuse Mixed Cell Lymphoma
- Recurrent Adult Diffuse Small Cleaved Cell Lymphoma
- Recurrent Adult Hodgkin Lymphoma
- Recurrent Adult Immunoblastic Lymphoma
- Recurrent Adult Lymphoblastic Lymphoma
- Recurrent Childhood Acute Lymphoblastic Leukemia
- Recurrent Childhood Acute Myeloid Leukemia
- Recurrent Childhood Anaplastic Large Cell Lymphoma
- Recurrent Childhood Burkitt Lymphoma
- Recurrent Childhood Hodgkin Lymphoma
- Recurrent Childhood Large Cell Lymphoma
- Recurrent Childhood Lymphoblastic Lymphoma
- Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive
- Recurrent Grade 1 Follicular Lymphoma
- Recurrent Grade 2 Follicular Lymphoma
- Recurrent Grade 3 Follicular Lymphoma
- Recurrent Mantle Cell Lymphoma
- Recurrent Marginal Zone Lymphoma
- Recurrent Small Lymphocytic Lymphoma
- Refractory Chronic Lymphocytic Leukemia
- Refractory Plasma Cell Myeloma
- Secondary Myelodysplastic Syndrome
- Stage I Adult Burkitt Lymphoma
- Stage I Adult Diffuse Large Cell Lymphoma
- Stage I Adult Diffuse Mixed Cell Lymphoma
- Stage I Adult Immunoblastic Lymphoma
- Stage I Adult Lymphoblastic Lymphoma
- Stage I Childhood Anaplastic Large Cell Lymphoma
- Stage I Childhood Burkitt Lymphoma
- Stage I Childhood Large Cell Lymphoma
- Stage I Childhood Lymphoblastic Lymphoma
- Stage I Grade 1 Follicular Lymphoma
- Stage II Adult Contiguous Immunoblastic Lymphoma
- Stage II Adult Non-Contiguous Immunoblastic Lymphoma
- Stage II Contiguous Adult Burkitt Lymphoma
- Stage II Contiguous Adult Diffuse Large Cell Lymphoma
- Stage II Contiguous Adult Diffuse Mixed Cell Lymphoma
- Stage II Contiguous Adult Diffuse Small Cleaved Cell Lymphoma
- Stage II Contiguous Adult Lymphoblastic Lymphoma
- Stage II Contiguous Mantle Cell Lymphoma
- Stage II Grade 1 Contiguous Follicular Lymphoma
- Stage II Grade 1 Non-Contiguous Follicular Lymphoma
- Stage II Grade 2 Contiguous Follicular Lymphoma
- Stage II Grade 2 Non-Contiguous Follicular Lymphoma
- Stage II Grade 3 Contiguous Follicular Lymphoma
- Stage II Grade 3 Non-Contiguous Follicular Lymphoma
- Stage II Non-Contiguous Adult Burkitt Lymphoma
- Stage II Non-Contiguous Adult Diffuse Large Cell Lymphoma
- Stage II Non-Contiguous Adult Diffuse Mixed Cell Lymphoma
- Stage II Non-Contiguous Adult Diffuse Small Cleaved Cell Lymphoma
- Stage II Non-Contiguous Adult Lymphoblastic Lymphoma
- Stage II Non-Contiguous Mantle Cell Lymphoma
- Stage II Small Lymphocytic Lymphoma
- Waldenstrom Macroglobulinemia
Interventions
Not listed
Eligibility (public fields only)
- Age range
- Not listed
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 31, 2004
- Primary completion
- Apr 30, 2011
- Completion
- May 7, 2015
- Last update posted
- Oct 29, 2019
2004 – 2015
United States locations
- U.S. sites
- 7
- U.S. states
- 5
- U.S. cities
- 5
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Presbyterian - Saint Lukes Medical Center - Health One | Denver | Colorado | 80218 | — |
| Emory University/Winship Cancer Institute | Atlanta | Georgia | 30322 | — |
| Huntsman Cancer Institute/University of Utah | Salt Lake City | Utah | 84112 | — |
| LDS Hospital | Salt Lake City | Utah | 84143 | — |
| Veterans Administration Center-Seattle | Seattle | Washington | 98108 | — |
| Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium | Seattle | Washington | 98109 | — |
| Froedtert and the Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00105001, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 29, 2019 · Synced May 18, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00105001 live on ClinicalTrials.gov.