Rituximab for the Treatment of Refractory Adult and Juvenile Dermatomyositis (DM) and Adult Polymyositis (PM)
Public ClinicalTrials.gov record NCT00106184. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Rituximab Therapy in Refractory Adult and Juvenile Idiopathic Inflammatory Myopathy (IIM)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Rituximab is a man-made antibody used to treat certain types of cancer. This study will determine whether rituximab is an effective treatment for adult and pediatric patients with dermatomyositis or polymyositis. Study hypotheses: 1) The time to improvement in Group A patients (receiving rituximab first) will occur significantly earlier than in Group B patients (receiving rituximab later). 2) The proportion of patients improved at Week 8 of the treatment phase will be significantly greater in Group A than in Group B.
Study identification
- NCT ID
- NCT00106184
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 200 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 5 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 2006 (Type not available)
- Primary completion
- Feb 2010 (Actual)
- Completion
- Aug 2010 (Actual)
- Last update posted
- Mar 4, 2015
2006 – 2010
United States locations
- U.S. sites
- 27
- U.S. states
- 16
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama Arthritis Intervention Program (Adult Site) | Birmingham | Alabama | 35294 | — |
| Phoenix Neurological Associates, LTD (Adult Site) | Phoenix | Arizona | 85006 | — |
| Cedars-Sinai Medical Center (Adult Site) | Los Angeles | California | 90048 | — |
| Stanford University (Adult Site) | Stanford | California | 94305 | — |
| Stanford University (Pediatric Site) | Stanford | California | 94305 | — |
| University of Miami School of Medicine (Adult Site) | Miami | Florida | 33136 | — |
| Miami Children's Hospital (Pediatric Site) | Miami | Florida | 33155 | — |
| University of Kansas Medical Center (Adult Site) | Kansas City | Kansas | 66160 | — |
| Kentucky Clinic (Adult Site) | Lexington | Kentucky | 40536 | — |
| National Institute of Health (Adult Site) | Bethesda | Maryland | 20892 | — |
| National Institute of Health (Pediatric Site) | Bethesda | Maryland | 20892 | — |
| Children's Hospital of Boston (Pediatric Site) | Boston | Massachusetts | 02115 | — |
| Beth Israel Deaconess Medical Center (Adult Site) | Boston | Massachusetts | 02215 | — |
| University of Michigan Health System (Adult Site) | Ann Arbor | Michigan | 48109 | — |
| Michigan State University (Adult and Pediatric Site) | Grand Rapids | Michigan | 49546 | — |
| Mayo Clinic (Adult Site) | Rochester | Minnesota | 55905 | — |
| Mayo Clinic (Pediatric Site) | Rochester | Minnesota | 55905 | — |
| North Shore Long Island Jewish Health System (Adult Site) | Lake Success | New York | 11042 | — |
| Hospital for Special Surgery (Adult Site) | New York | New York | 10021 | — |
| Duke University Medical Center (Pediatric Site) | Durham | North Carolina | 27710 | — |
| Cincinnati's Children's Hospital (Pediatric Site) | Cincinnati | Ohio | 45229 | — |
| Children's Hospital of Philadelphia (Pediatric Site) | Philadelphia | Pennsylvania | 19104 | — |
| University of Pennsylvania (Adult Site) | Philadelphia | Pennsylvania | 19104 | — |
| Children's Hospital of Pittsburgh (Pediatric Site) | Pittsburgh | Pennsylvania | 15213 | — |
| University of Pittsburgh / UPMC (Adult Site) | Pittsburgh | Pennsylvania | 15261 | — |
| University of Texas Southwestern Medical Center (Adult) | Dallas | Texas | 75390-8884 | — |
| Medical College of Wisconsin / Froedtert Memorial Luthern Hospital (Adult Site) | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00106184, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 4, 2015 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00106184 live on ClinicalTrials.gov.