Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection
Public ClinicalTrials.gov record NCT00195351. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Open-Label, Randomized Comparative Study of Tigecycline vs Ceftriaxone Sodium Plus Metronidazole for the Treatment of Hospitalized Subjects With Complicated Intra-abdominal Infection
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a phase 3b/4 randomized, open-label, comparative, multicenter study of the safety and efficacy of tigecycline to ceftriaxone sodium plus metronidazole in hospitalized subjects with cIAI (Complicated Intra-Abdominal Infection). Subjects with clinical signs and symptoms of cIAI will be included for enrollment. Subjects will be stratified at randomization for Acute Physiologic and Chronic Health Evaluation scale (APACHE II) score \< 10 and \> 10. Subjects will be followed for efficacy through the test-of-cure assessment. Safety evaluations will occur through the treatment and post-treatment periods and continue through resolution or stability of the adverse event(s).
Study identification
- NCT ID
- NCT00195351
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 467 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 2005 (Type not available)
- Primary completion
- Feb 2008 (Actual)
- Completion
- Feb 2008 (Actual)
- Last update posted
- Feb 25, 2013
2005 – 2008
United States locations
- U.S. sites
- 46
- U.S. states
- 26
- U.S. cities
- 41
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Mobile | Alabama | 36617 | — |
| Not listed | Laguna Hills | California | 92653 | — |
| Not listed | Los Angeles | California | 90033 | — |
| Not listed | Orange | California | 92868 | — |
| Not listed | Palm Springs | California | 92262 | — |
| Not listed | San Diego | California | 92134 | — |
| Not listed | Torrance | California | 90509 | — |
| Not listed | Denver | Colorado | 80204 | — |
| Not listed | Denver | Colorado | 80262 | — |
| Not listed | Hartford | Connecticut | 06102 | — |
| Not listed | Newark | Delaware | 19718 | — |
| Not listed | Washington D.C. | District of Columbia | 20037 | — |
| Not listed | Miami | Florida | 33136 | — |
| Not listed | Atlanta | Georgia | 30342 | — |
| Not listed | Honolulu | Hawaii | 96813 | — |
| Not listed | Chicago | Illinois | 60612 | — |
| Not listed | Indianapolis | Indiana | 46202 | — |
| Not listed | Indianapolis | Indiana | 46280 | — |
| Not listed | Boston | Massachusetts | 02118 | — |
| Not listed | Springfield | Massachusetts | 01199 | — |
| Not listed | West Roxbury | Massachusetts | 02132 | — |
| Not listed | Detroit | Michigan | 48201 | — |
| Not listed | Grand Rapids | Michigan | 49506 | — |
| Not listed | Minneapolis | Minnesota | 55422 | — |
| Not listed | St Louis | Missouri | 63110 | — |
| Not listed | St Louis | Missouri | 63131 | — |
| Not listed | Butte | Montana | 59701 | — |
| Not listed | Lincoln | Nebraska | 68510 | — |
| Not listed | Laconia | New Hampshire | 03246 | — |
| Not listed | Buffalo | New York | 14215 | — |
| Not listed | Bismarck | North Dakota | 58501 | — |
| Not listed | Fargo | North Dakota | 58122 | — |
| Not listed | Cleveland | Ohio | 44109 | — |
| Not listed | Columbus | Ohio | 43210 | — |
| Not listed | Columbus | Ohio | 43215 | — |
| Not listed | Toledo | Ohio | 43608 | — |
| Not listed | Zanesville | Ohio | 43701 | — |
| Not listed | Pittsburgh | Pennsylvania | 15261 | — |
| Not listed | Corsiana | Texas | 75151 | — |
| Not listed | Fort Worth | Texas | 76135 | — |
| Not listed | Houston | Texas | 77026 | — |
| Not listed | Houston | Texas | 77030 | — |
| Not listed | Salt Lake City | Utah | 84102 | — |
| Not listed | Charlottesville | Virginia | 22906 | — |
| Not listed | Madison | Wisconsin | 53792 | — |
| Not listed | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 20 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00195351, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 25, 2013 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00195351 live on ClinicalTrials.gov.