Study of Rebamipide Eye Drops to Treat Dry Eye
Public ClinicalTrials.gov record NCT00201955. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Rebamipide Ophthalmic Suspension in the Treatment of Dry Eye: A Multicenter, Phase 3, Randomized, Double-Masked, Placebo-Controlled, Parallel-Group, 26 Week Study
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine the potential safety and effectiveness of rebamipide eye drops, an investigational eye drop being developed for the treatment of keratoconjunctivitis sicca (dry eye).
Study identification
- NCT ID
- NCT00201955
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 762 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 1, 2004 (Actual)
- Primary completion
- Jul 1, 2006 (Actual)
- Completion
- Jul 1, 2006 (Actual)
- Last update posted
- Jun 24, 2026
2004 – 2006
United States locations
- U.S. sites
- 60
- U.S. states
- 26
- U.S. cities
- 50
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Harold Helms, MD | Birmingham | Alabama | 35205 | — |
| Michael Bernstein, MD | Birmingham | Alabama | 35216 | — |
| I Care! Eye Care! | Flagstaff | Arizona | 860001 | — |
| Harvey and Bernice Jones Eye Institute | Little Rock | Arkansas | 72205 | — |
| United Medical Research Institute | Inglewood | California | 90301 | — |
| Benchmark Research | San Francisco | California | 94102 | — |
| Southern California Clinical Research, Inc. | San Marino | California | 91108 | — |
| Colorado Eye Associates, PC | Colorado Springs | Colorado | 80907 | — |
| Danbury Eye Physicians and Surgeons, P.C. | Danbury | Connecticut | 06810-4005 | — |
| Florida Ophthalmic Institute | Gainesville | Florida | 32605-3192 | — |
| Florida Wellcare Alliance, L.C. | Inverness | Florida | 34452 | — |
| Shettle Eye Center | Largo | Florida | 33770 | — |
| Suncoast Clinical Research, Inc. | New Port Richey | Florida | 34652 | — |
| Tukio Institute for Clinical Research | North Miami Beach | Florida | 33169 | — |
| Magnolia Research Group, Inc. | Ocala | Florida | 34471 | — |
| Radiant Research - West Palm Beach | West Palm Beach | Florida | 33407 | — |
| Vision Incorporated | Savannah | Georgia | 31406 | — |
| Welborn Clinic | Evansville | Indiana | 47714 | — |
| Heartland Research Associates, LLC | Wichita | Kansas | 67207 | — |
| Wichita Clinic, PA | Wichita | Kansas | 67208 | — |
| Taustine Eye Center | Louisville | Kentucky | 40217 | — |
| Bossier Optical, Inc. | Bossier City | Louisiana | 71111 | — |
| Stevenson Medical Surgical Eye Center | New Orleans | Louisiana | 70119 | — |
| Family Eye Centers | New Orleans | Louisiana | 70127 | — |
| Ophthalmic Research Associates, Inc. | North Andover | Massachusetts | 01845 | — |
| Minnesota Eye Associates | Minneapolis | Minnesota | 55404 | — |
| Depremont Eye Specialists | Gulfport | Mississippi | 39507 | — |
| Opthalmology Associates | Creve Coeur | Missouri | 63141 | — |
| Clinical Research Laboratories | Piscataway | New Jersey | 08854 | — |
| Ophthalmology Associates | Princeton | New Jersey | 08540 | — |
| Eye Care Associates | Bethpage | New York | 11021 | — |
| Ophthmalmic Consultants of Long Island | Lynbrook | New York | 11563 | — |
| Mt. Sinai Medical Center School of Medicine | New York | New York | 10029 | — |
| Ophthalmic Consultants of Long Island | New York | New York | 11570 | — |
| Rochester Ophthalmological Group | Rochester | New York | 14618 | — |
| Ophthalmic Consultants of Long Island | Valley Stream | New York | 11581 | — |
| Western Wake Eye Center, P.A. | Cary | North Carolina | 27511 | — |
| Southeast Clinical Research Associates | Charlotte | North Carolina | 28210 | — |
| Horizon Eye Care - Clinical Research Dept. | Charlotte | North Carolina | 28211 | — |
| Cornerstone Research Care | High Point | North Carolina | 27262 | — |
| Carolina Eye Associates | Southern Pines | North Carolina | 28387 | — |
| Cincinnati Eye Institute | Cincinnati | Ohio | 45242 | — |
| Comprehensive Opthalmology & Optical Services | Cleveland | Ohio | 44115 | — |
| Bend Medical Clinic | Bend | Oregon | 97701 | — |
| Medical Eye Center | Medford | Oregon | 97504 | — |
| Valley Clinical Research Center | Easton | Pennsylvania | 18045 | — |
| Philadelphia Eye Associates | Philadelphia | Pennsylvania | 19148 | — |
| University of Pittsburg Eye and Ear Institute | Pittsburgh | Pennsylvania | 15233 | — |
| Glaucome-Cataract Consultants | Pittsburgh | Pennsylvania | 15243 | — |
| Black Hills Regional Eye Institute | Rapid City | South Dakota | 57701 | — |
| Total Eye Care, P.A. | Memphis | Tennessee | 38119 | — |
| Corona Research Consultants, Inc. | El Paso | Texas | 79904 | — |
| The University of Texas Medical Branch | Galveston | Texas | 77555 | — |
| Physician Research Network | Houston | Texas | 77002 | — |
| Not listed | Houston | Texas | 77002 | — |
| Medical Center Ophthalmology | Houston | Texas | 77030 | — |
| Houston Eye Associates | Houston | Texas | 77125 | — |
| Sun Research Institute | San Antonio | Texas | 78205 | — |
| Eye Clinic of South Texas | San Antonio | Texas | 78209 | — |
| Advanced Healthcare Clinical Research Center | Milwaukee | Wisconsin | 21209 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00201955, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 24, 2026 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00201955 live on ClinicalTrials.gov.