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Withdrawn Phase 3 Interventional

XERECEPT® (hCRF) for Primary Glioma Patients Requiring Dexamethasone to Treat Peritumoral Brain Edema

ClinicalTrials.gov ID: NCT00226668

Public ClinicalTrials.gov record NCT00226668. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 21, 2026, 2:55 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase III Randomized, Double-Blind Study Comparing Human Corticotropin-Releasing Factor (hCRF) to Dexamethasone for Control of Symptoms Associated With Peritumoral Brain Edema in Patients With Primary Malignant Glioma

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to examine the safety and efficacy of XERECEPT (human Corticotropin-Releasing Factor, or hCRF) compared to dexamethasone in patients with primary malignant glioma who require increased dexamethasone doses to control symptom of peritumoral brain edema.

Study identification

NCT ID
NCT00226668
Recruitment status
Withdrawn
Study type
Interventional
Phase
Phase 3
Enrollment
120 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 2006 (Type not available)
Primary completion
Not listed
Completion
Jan 2008 (Estimated)
Last update posted
Jan 3, 2008

2006 – 2008

United States locations

U.S. sites
24
U.S. states
15
U.S. cities
23
Facility City State ZIP Site status
Barrow Neurological Institute Phoenix Arizona 85013 —
UC San Diego Cancer Center La Jolla California 92093 —
Hoag Memorial Hospital Presbyterian Newport Beach California 92658 —
Stanford University Medical Center Palo Alto California 94305 —
UC Davis Medical Center Sacramento California 95817 —
University of Colorado Cancer Center Aurora Colorado 80045 —
Moffitt Cancer Center and Research Tampa Florida 33612 —
Winship Cancer Institute, Emory University Atlanta Georgia 30322 —
Northwestern University, Feinberg School of Medicine Chicago Illinois 60611 —
Evanston Northwestern Healthcare Evanston Illinois 60201 —
Beth Israel Deaconess Med Center Boston Massachusetts 02215 —
Field Neurosciences Institute Saginaw Michigan 48604 —
Neurology Group of Bergen County Ridgewood New Jersey 07450 —
Dent Neurologic Institute Amherst New York 14226 —
Weill Medical College of Cornell University New York New York 10021 —
Wake Forest University Winston-Salem North Carolina 27106 —
University Hematology Oncology Care, LLC Cincinnati Ohio 43210 —
Good Samaritan Hospital Cincinnati Ohio 45220 —
The Ohio State University Columbus Ohio 43210 —
Oregon Clinic Portland Oregon 97210 —
Methodist Healthcare - University Hospital Memphis Tennessee 38103 —
Vanderbilt University Medical Center Nashville Tennessee 37232 —
University of Wisconsin Madison Wisconsin 53792 —
Medical College of Wisconsin Milwaukee Wisconsin 53226-3596 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00226668, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 3, 2008 · Synced Oct 21, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00226668 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →