ClinicalTrials.gov record
A Phase IV Study of the Safety and Efficacy of Aripiprazole in Combination With Lamotrigine in the Long-Term Maintenance Treatment of Patients With Bipolar I Disorder With A Recent Manic or Mixed Episode
ClinicalTrials.gov ID: NCT00277212
Public ClinicalTrials.gov record NCT00277212. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 20, 2026, 11:39 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Double-blind, Study of the Efficacy and Safety of Aripiprazole in Combination With Lamotrigine in the Long-term Maintenance Treatment of Patients With Bipolar I Disorder With a Recent Manic or Mixed Episode
Study identification
- NCT ID
- NCT00277212
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Lead sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
- Industry
- Enrollment
- 1,169 participants
Conditions and interventions
Conditions
Interventions
- Lamotrigine + Aripiprazole Drug
- Lamotrigine + Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 30, 2005
- Primary completion
- Jun 30, 2009
- Completion
- Jun 30, 2009
- Last update posted
- May 12, 2026
2005 – 2009
United States locations
- U.S. sites
- 62
- U.S. states
- 26
- U.S. cities
- 58
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University Of Alabama At Birmingham | Birmingham | Alabama | 35205 | — |
| Southwest Biomedical Research Foundation | Tucson | Arizona | 85712 | — |
| Pravin Kansagra, M.D. | Anaheim | California | 92801 | — |
| College Hospital Costa Mesa | Costa Mesa | California | 92627 | — |
| Pacific Institute For Medical Research, Inc. | Los Angeles | California | 90024 | — |
| Excell Research | Oceanside | California | 92056 | — |
| Southern Ca Clinical Research, Inc. | Pasadena | California | 91106 | — |
| Stanford University | Stanford | California | 94305 | — |
| Los Angeles Biomedical Research Institute | Torrance | California | 90502 | — |
| Pacific Clinical Research Medical Group | Upland | California | 91786 | — |
| Health Sciences America, Llc | Boca Raton | Florida | 33432 | — |
| Cns Clinical Research Group | Coral Springs | Florida | 33065 | — |
| Act Clinical Research Institute, Llc | Daytona Beach | Florida | 32124 | — |
| Neuropsychiatric Research Center Of Southwest Florida | Fort Myers | Florida | 33912 | — |
| Aurora-Cuervo Clinical Trials | Miami | Florida | 33143 | — |
| Gulf Coast Medical Research | Port Charlotte | Florida | 33952 | — |
| Janus Center For Psychiatric Research | West Palm Beach | Florida | 33407 | — |
| Comprehensive Neuroscience, Inc | Atlanta | Georgia | 30328 | — |
| Valle Vista Health System | Greenwood | Indiana | 46143 | — |
| Clinco | Terre Haute | Indiana | 47802 | — |
| Clinical Trials Technology, Inc | Prairie Village | Kansas | 66206 | — |
| Clinical Research Institute | Wichita | Kansas | 67213 | — |
| University Of Kentucky, Dept. Of Psychiatry | Lexington | Kentucky | 40509 | — |
| Owensboro Behavioral Care | Owensboro | Kentucky | 42301 | — |
| Sheppard Pratt Health System | Baltimore | Maryland | 21285 | — |
| Clinical Insights | Glen Burnie | Maryland | 21061 | — |
| Capital Clinical Research Associates | Rockville | Maryland | 20852 | — |
| Psychopharmacology Research Corporation | Farmington Hills | Michigan | 48334 | — |
| University Of Minnesota | Minneapolis | Minnesota | 55455 | — |
| Regions Hospital | Saint Paul | Minnesota | 55101 | — |
| Precise Research Centers | Flowood | Mississippi | 39232 | — |
| University Of Medicine & Dentistry Of New Jersey | Cherry Hill | New Jersey | 08002 | — |
| Buffalo Psychiatric Center | Buffalo | New York | 14213 | — |
| Finger Lakes Clinical Research | Rochester | New York | 14618 | — |
| Richmond Behavioral Associates | Staten Island | New York | 10312 | — |
| Duke University Medical Center | Durham | North Carolina | 27705 | — |
| Zarzar Psychiatric Associates, Pllc | Raleigh | North Carolina | 27607 | — |
| Horizon Medical Services | Bismarck | North Dakota | 58501 | — |
| Neuro Behavioral Clinical Research, Inc. | Canton | Ohio | 44708 | — |
| Community Research | Cincinnati | Ohio | 45227 | — |
| Saroj Brar Md, Inc | Cleveland | Ohio | 44113 | — |
| University Of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | — |
| Cutting Edge Research | Oklahoma City | Oklahoma | 73116 | — |
| Summit Research Network | Portland | Oregon | 97210 | — |
| Lehigh Valley Hospital | Allentown | Pennsylvania | 18103 | — |
| Lehigh Center For Clinical Research | Allentown | Pennsylvania | 18104 | — |
| Dubois Regional Medical Center | DuBois | Pennsylvania | 15801 | — |
| Freimer, Martin | East Stroudsburg | Pennsylvania | 18301 | — |
| University Of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Belmont Center For Comprehensive Treatment | Philadelphia | Pennsylvania | 19131 | — |
| Cns Research Institute | Philadelphia | Pennsylvania | 19149 | — |
| Ut Medical Group/Odyssey Research | Memphis | Tennessee | 38105 | — |
| Psychiatric Consultants, Pc | Nashville | Tennessee | 37203 | — |
| Harmony Research, Llc | Piney Flats | Tennessee | 37686 | — |
| Bayou City Research, Ltd. | Houston | Texas | 77007 | — |
| Alamo Superior Research | San Antonio | Texas | 78229 | — |
| University Of Virginia Health System | Charlottesville | Virginia | 22903 | — |
| Windwood Centre | Virginia Beach | Virginia | 23452 | — |
| Pacific Institute Of Medical Sciences | Bothell | Washington | 98011 | — |
| Summit Research Network (Seattle) Llc | Seattle | Washington | 98104 | — |
| Health Research Center | Morgantown | West Virginia | 26506 | — |
| Aurora Health Care | Milwaukee | Wisconsin | 53233 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00277212, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 12, 2026 · Synced May 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00277212 live on ClinicalTrials.gov.