ClinicalTrials.gov record
Not listed Phase 1Phase 2 Interventional

Methotrexate, Mannitol, Rituximab, and Carboplatin in Treating Patients With Newly Diagnosed Primary Central Nervous System Lymphoma

ClinicalTrials.gov ID: NCT00293475

Public ClinicalTrials.gov record NCT00293475. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 20, 2026, 1:19 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase I/II Study of Patients With Newly Diagnosed Primary Central Nervous System Lymphoma Treated With Methotrexate/BBBD, and Adding Rituximab (an Anti CD-20 Antibody) and Carboplatin, to the Treatment Regimen

Study identification

NCT ID
NCT00293475
Recruitment status
Not listed
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
OHSU Knight Cancer Institute
Other
Enrollment
81 participants

Conditions and interventions

Interventions

  • Carboplatin Drug
  • Mannitol Drug
  • Methotrexate Drug
  • Quality-of-Life Assessment Other
  • Rituximab Biological
  • Sodium Thiosulfate Drug

Drug · Other · Biological

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 13, 2005
Primary completion
Jan 30, 2022
Completion
Jan 30, 2023
Last update posted
Sep 21, 2021

2005 – 2023

United States locations

U.S. sites
4
U.S. states
2
U.S. cities
4
Facility City State ZIP Site status
Good Samaritan Hospital - Cincinnati Cincinnati Ohio 45220
Cleveland Clinic Foundation Cleveland Ohio 44195
Ohio State University Comprehensive Cancer Center Columbus Ohio 43210
OHSU Knight Cancer Institute Portland Oregon 97239

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00293475, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 21, 2021 · Synced May 20, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00293475 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →