Multicenter Selective Lymphadenectomy Trial II (MSLT-II)
Public ClinicalTrials.gov record NCT00297895. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III Multicenter Randomized Trial of Sentinel Lymphadenectomy and Complete Lymph Node Dissection Versus Sentinel Lymphadenectomy Alone in Cutaneous Melanoma Patients With Molecular or Histopathological Evidence of Metastases in the Sentinel Node
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Subjects must be diagnosed with melanoma. All subjects receive sentinel lymphadenectomy. If the subject is sentinel node positive and meets study requirements, the subject is randomized to receive either (1) completion lymphadenectomy (2) observation with nodal ultrasound. Subjects are then followed for 10 years.
Study identification
- NCT ID
- NCT00297895
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 1,939 participants
Conditions and interventions
Conditions
Interventions
- Completion Lymphadenectomy Procedure
- Monitoring with nodal ultrasound Procedure
Procedure
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 30, 2004 (Actual)
- Primary completion
- Sep 30, 2019 (Actual)
- Completion
- Sep 30, 2019 (Actual)
- Last update posted
- May 13, 2022
2004 – 2019
United States locations
- U.S. sites
- 39
- U.S. states
- 20
- U.S. cities
- 34
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Sharp Hospital | San Diego | California | 92123 | — |
| John Wayne Cancer Institute | Santa Monica | California | 90404 | — |
| Memorial Hospital - Colorado Springs | Colorado Springs | Colorado | 809030-3658 | — |
| Lakeland Regional Cancer Center | Lakeland | Florida | 33805 | — |
| H. Lee Moffitt Cancer Center | Tampa | Florida | 33612-9497 | — |
| Northwestern University Feinberg School of Medicine | Chicago | Illinois | 60611 | — |
| Rush University | Chicago | Illinois | 60612-3824 | — |
| University of Louisville | Louisville | Kentucky | 40202 | — |
| Mercy Medical Center | Baltimore | Maryland | 21202 | — |
| Johns Hopkins Medical Institute | Baltimore | Maryland | 21287 | — |
| University of Michigan | Ann Arbor | Michigan | 48109-0932 | — |
| St. Louis University | St Louis | Missouri | 63110-8566 | — |
| Dartmouth-Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| Buffalo General Hospital | Buffalo | New York | 14209 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263-0001 | — |
| Feinstein Institute for Medical Research | Great Neck | New York | 11021 | — |
| Memorial Sloan-Kettering Cancer Center | New York | New York | 10065 | — |
| SUNY at Stony Brook Hospital Medical Center | Stony Brook | New York | 11794-8191 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Wake Forest University | Winston-Salem | North Carolina | 27157 | — |
| University of Cincinnati | Cincinnati | Ohio | 45219 | — |
| Ohio State University | Columbus | Ohio | 43210 | — |
| St. Luke's Hospital | Bethlehem | Pennsylvania | 18015 | — |
| Geisinger Clinic | Danville | Pennsylvania | 17822 | — |
| Pennsylvania State Hershey Cancer Institute | Hershey | Pennsylvania | 17033 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | — |
| Main Line Surgeons | Wynnewood | Pennsylvania | 19096 | — |
| Greenville Hospital System Cancer Center | Greenville | South Carolina | 29605 | — |
| University of Tennessee Medical Center | Knoxville | Tennessee | 37920 | — |
| Vanderbilt University | Nashville | Tennessee | 37232-6868 | — |
| Dallas Surgical Group | Dallas | Texas | 75235 | — |
| MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| IHC Cancer Services Intermountain Medical Center | Salt Lake City | Utah | 84103 | — |
| Hunstman Cancer Institute | Salt Lake City | Utah | 84112 | — |
| University of Virginia | Charlottesville | Virginia | 22908 | — |
| Sentara Careplex Hospital | Newport News | Virginia | 23606 | — |
| University of Washington | Seattle | Washington | 98195 | — |
| University of Wisconsin | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 24 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00297895, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 13, 2022 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00297895 live on ClinicalTrials.gov.