Safety and Efficacy of Buprenorphine Transdermal System in Subjects With Moderate to Severe Osteoarthritis of Hip or Knee
Public ClinicalTrials.gov record NCT00313846. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Study to Determine the Efficacy and Safety of the Buprenorphine Transdermal Delivery System in Subjects With Moderate to Severe Osteoarthritic Pain of Hip or Knee
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The objective of this study is to demonstrate the effectiveness and tolerability of the buprenorphine transdermal system (BTDS) (5, 10 and 20) in comparison to placebo transdermal system in subjects with moderate to severe osteoarthritis pain of the hip and knee currently treated with oral opioids. The double-blind treatment intervention duration is 4 weeks during which time supplemental analgesic medication (acetaminophen) will be provided to all subjects in addition to study drug.
Study identification
- NCT ID
- NCT00313846
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 529 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 40 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 2003 (Type not available)
- Primary completion
- Jun 2004 (Actual)
- Completion
- Jun 2004 (Actual)
- Last update posted
- Sep 3, 2012
2003 – 2004
United States locations
- U.S. sites
- 44
- U.S. states
- 18
- U.S. cities
- 41
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Vista Medical Research | Mesa | Arizona | 85206 | — |
| Arizona Research Center | Phoenix | Arizona | 85012 | — |
| Radiant Research | Phoenix | Arizona | 85013 | — |
| Arizona Research Center | Phoenix | Arizona | 85023 | — |
| ACRC/Arizona Clinical Research | Tucson | Arizona | 85715 | — |
| Advance Pain Medicine | Bakersfield | California | 93311 | — |
| Eastgate Medical Center | Cypress | California | 90623 | — |
| University Osteoporosis Ctr | Loma Linda | California | 92354 | — |
| San Diego Arthritis & Osteoporosis Medical Clinic | San Diego | California | 92108 | — |
| Scripps Clinic Rancho Bernard | San Diego | California | 92128 | — |
| CNS Clinical Trials, Inc | San Francisco | California | 94121 | — |
| Mountain View Clinical Research | Denver | Colorado | 80209 | — |
| Integrative Treatment Centers/Rocky Mtn Clin Res | Westminster | Colorado | 80021 | — |
| Rocky Mountain Center for Clinical Research | Wheat Ridge | Colorado | 80033 | — |
| Stamford Therapeutic Consortium | Bridgeport | Connecticut | 66060 | — |
| Medical Specialists of the Palm Beaches | Atlantis | Florida | 33462 | — |
| University Clinical Research Deland | DeLand | Florida | 32720 | — |
| Drug Study Institute | Jupiter | Florida | 33458 | — |
| Coastal Medical Research | Orange City | Florida | 32763 | — |
| Coastal Medical Research | Port Orange | Florida | 32127 | — |
| Palm Beach Research Center | West Palm Beach | Florida | 33409 | — |
| Gold Coast Research | Weston | Florida | 33331 | — |
| Non-Surgical Orthopedic & Spine Center | Marietta | Georgia | 30060 | — |
| Columbus Internal Medical Associates | Columbus | Indiana | 47201 | — |
| MediSphere Medical Research Ctr. | Evansville | Indiana | 47714 | — |
| Primary Care Research | Murray | Kentucky | 42071 | — |
| Professional Clinical Research | Cadillac | Michigan | 49601 | — |
| Sound Medical At West Front Primary Care | Traverse City | Michigan | 49684 | — |
| Beth Israel Med Ctr Dept of Pain Medicine & Palliative Care | New York | New York | 10003 | — |
| All-Trials Clinical Research, LLC | Winston-Salem | North Carolina | 27103 | — |
| Keystone Clinical | Altoona | Pennsylvania | 16602 | — |
| Altoona Center for Clinical Research | Duncansville | Pennsylvania | 16635 | — |
| University Orthopedics Center | State College | Pennsylvania | 16801 | — |
| Clinical Research Center of Reading, LLP | West Reading | Pennsylvania | 19611 | — |
| Low Country Rheumatology | Charleston | South Carolina | 29406 | — |
| Brown Clinic | Watertown | South Dakota | 57201 | — |
| Private Practice | Dallas | Texas | 75251 | — |
| Team Research of Central Texas | Harker Heights | Texas | 76548 | — |
| Radiant Research San Antonio Northeast | San Antonio | Texas | 78217 | — |
| ACCU Clinical Research Trials, Inc | Seguin | Texas | 78155 | — |
| Wasatch Clinical Research | Salt Lake City | Utah | 84107 | — |
| Advance Pain Management & Rehab | Virgina Beach | Virginia | 23454 | — |
| Evergreen Clinical Research Associates | Edmonds | Washington | 98026 | — |
| Internal Medicine Northwest | Tacoma | Washington | 98405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00313846, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 3, 2012 · Synced Oct 24, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00313846 live on ClinicalTrials.gov.