Combination Chemotherapy, Radiation Therapy, and Bevacizumab in Treating Patients With Newly Diagnosed Stage III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery
Public ClinicalTrials.gov record NCT00334815. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Pilot Trial of Cisplatin/Etoposide/Radiotherapy Followed by Consolidation Docetaxel and the Addition of Bevacizumab (NSC-704865) in Three Cohorts of Patients With Inoperable Locally Advanced Stage III Non-small Cell Lung Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This clinical trial studies combination chemotherapy, radiation therapy, and bevacizumab in treating patients with newly diagnosed stage III non-small cell lung cancer that cannot be removed by surgery. Drugs used in chemotherapy, such as cisplatin, etoposide, and docetaxel, work in different ways to stop the growth of \[cancer/tumor\] cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Radiation therapy uses high-energy x-rays to kill tumor cells. Monoclonal antibodies, such as bevacizumab, may interfere with the ability of tumor cells to grow and spread. Bevacizumab may also stop the growth of tumor cells by blocking blood flow to the tumor. Giving more than one drug (combination chemotherapy) together with radiation therapy and bevacizumab may kill more tumor cells.
Study identification
- NCT ID
- NCT00334815
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 29 participants
Conditions and interventions
Conditions
Interventions
- Bevacizumab Biological
- Cisplatin Drug
- Docetaxel Drug
- Etoposide Drug
- Filgrastim Biological
- Pegfilgrastim Biological
- Radiation Therapy Radiation
Biological · Drug · Radiation
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 15, 2006 (Actual)
- Primary completion
- Jul 1, 2014 (Actual)
- Completion
- Feb 22, 2027 (Estimated)
- Last update posted
- Aug 26, 2026
2006 – 2027
United States locations
- U.S. sites
- 61
- U.S. states
- 22
- U.S. cities
- 54
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Providence Hospital | Mobile | Alabama | 36608 | — |
| Saint Bernards Regional Medical Center | Jonesboro | Arkansas | 72401 | — |
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| Highlands Oncology Group - Rogers | Rogers | Arkansas | 72758 | — |
| USC / Norris Comprehensive Cancer Center | Los Angeles | California | 90033 | — |
| Fremont - Rideout Cancer Center | Marysville | California | 95901 | — |
| UC Irvine Health/Chao Family Comprehensive Cancer Center | Orange | California | 92868 | — |
| University of California Davis Comprehensive Cancer Center | Sacramento | California | 95817 | — |
| Providence Santa Rosa Memorial Hospital | Santa Rosa | California | 95405 | — |
| Gene Upshaw Memorial Tahoe Forest Cancer Center | Truckee | California | 96161 | — |
| Northbay Cancer Center | Vacaville | California | 95687 | — |
| Rocky Mountain Regional VA Medical Center | Aurora | Colorado | 80045 | — |
| UCHealth University of Colorado Hospital | Aurora | Colorado | 80045 | — |
| Denver Health Medical Center | Denver | Colorado | 80204 | — |
| Shaw Cancer Center | Edwards | Colorado | 81632 | — |
| Valley View Hospital Cancer Center | Glenwood Springs | Colorado | 81601 | — |
| Montrose Memorial Hospital | Montrose | Colorado | 81401 | — |
| Cancer Centers of Central Florida PA | Leesburg | Florida | 34788 | — |
| Lewis Cancer and Research Pavilion at Saint Joseph's/Candler | Savannah | Georgia | 31405 | — |
| Loyola University Medical Center | Maywood | Illinois | 60153 | — |
| Edward Hospital/Cancer Center | Naperville | Illinois | 60540 | — |
| HaysMed | Hays | Kansas | 67601 | — |
| Hutchinson Regional Medical Center | Hutchinson | Kansas | 67502 | — |
| University of Kansas Cancer Center | Kansas City | Kansas | 66160 | — |
| Olathe Cancer Center | Olathe | Kansas | 66061 | — |
| Salina Regional Health Center | Salina | Kansas | 67401 | — |
| University of Kansas Health System Saint Francis Campus | Topeka | Kansas | 66606 | — |
| LSU Health Sciences Center at Shreveport | Shreveport | Louisiana | 71103 | — |
| Highland Clinic | Shreveport | Louisiana | 71105 | — |
| Dana-Farber Cancer Institute at Boston Medical Center - Brighton | Brighton | Massachusetts | 02135 | — |
| Wayne State University/Karmanos Cancer Institute | Detroit | Michigan | 48201 | — |
| McLaren Cancer Institute-Macomb | Mount Clemens | Michigan | 48043 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | — |
| Kansas City Veterans Affairs Medical Center | Kansas City | Missouri | 64128 | — |
| Montana Cancer Consortium NCORP | Billings | Montana | 59102 | — |
| Benefis Sletten Cancer Institute | Great Falls | Montana | 59405 | — |
| Arnot Ogden Medical Center/Falck Cancer Center | Elmira | New York | 14905 | — |
| Highland Hospital | Rochester | New York | 14620 | — |
| University of Rochester | Rochester | New York | 14642 | — |
| Novant Health Presbyterian Medical Center | Charlotte | North Carolina | 28204 | — |
| Southeast Clinical Oncology Research Consortium NCORP | Winston-Salem | North Carolina | 27104 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| Portland VA Medical Center | Portland | Oregon | 97239 | — |
| Roper Hospital | Charleston | South Carolina | 29401 | — |
| Wellmont Holston Valley Hospital and Medical Center | Kingsport | Tennessee | 37660 | — |
| University of Tennessee Health Science Center | Memphis | Tennessee | 38163 | — |
| The Don and Sybil Harrington Cancer Center | Amarillo | Texas | 79106 | — |
| UT MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| Audie L Murphy VA Hospital | San Antonio | Texas | 78229 | — |
| University Hospital | San Antonio | Texas | 78229 | — |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78229 | — |
| Danville Regional Medical Center | Danville | Virginia | 24541 | — |
| Ballad Health Cancer Care - Norton | Norton | Virginia | 24273 | — |
| MultiCare Auburn Medical Center | Auburn | Washington | 98001 | — |
| Providence Regional Cancer System-Centralia | Centralia | Washington | 98531 | — |
| Saint Francis Hospital | Federal Way | Washington | 98003 | — |
| Saint Clare Hospital | Lakewood | Washington | 98499 | — |
| Providence - Saint Peter Hospital | Olympia | Washington | 98506-5166 | — |
| MultiCare Good Samaritan Hospital | Puyallup | Washington | 98372 | — |
| MultiCare Allenmore Hospital | Tacoma | Washington | 98405 | — |
| Saint Joseph Medical Center | Tacoma | Washington | 98405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00334815, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 26, 2026 · Synced Oct 18, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00334815 live on ClinicalTrials.gov.