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Completed Phase 1 Interventional

Vinblastine and Carboplatin in Treating Young Patients With Newly Diagnosed or Recurrent Low-Grade Glioma

ClinicalTrials.gov ID: NCT00352495

Public ClinicalTrials.gov record NCT00352495. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 20, 2026, 1:18 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase I Study of Vinblastine in Combination With Carboplatin for Children With Newly Diagnosed and Recurrent Low-Grade Gliomas

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

RATIONALE: Drugs used in chemotherapy, such as vinblastine and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells. PURPOSE: This phase I trial is studying the side effects and best dose of vinblastine when given together with carboplatin in treating young patients with newly diagnosed or recurrent low-grade glioma.

Study identification

NCT ID
NCT00352495
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Children's Oncology Group
Network
Enrollment
26 participants

Conditions and interventions

Eligibility (public fields only)

Age range
Up to 21 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 2006 (Type not available)
Primary completion
Sep 2011 (Actual)
Completion
Mar 2012 (Actual)
Last update posted
Feb 13, 2014

2006 – 2012

United States locations

U.S. sites
19
U.S. states
16
U.S. cities
19
Facility City State ZIP Site status
Lurleen Wallace Comprehensive Cancer at University of Alabama - Birmingham Birmingham Alabama 35294 —
Children's Hospital of Orange County Orange California 92868 —
Children's National Medical Center Washington D.C. District of Columbia 20010-2970 —
Children's Memorial Hospital - Chicago Chicago Illinois 60614 —
Indiana University Melvin and Bren Simon Cancer Center Indianapolis Indiana 46202-5289 —
Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute Boston Massachusetts 02115 —
C.S. Mott Children's Hospital at University of Michigan Medical Center Ann Arbor Michigan 48109-0286 —
Masonic Cancer Center at University of Minnesota Minneapolis Minnesota 55455 —
Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis St Louis Missouri 63110 —
Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center New York New York 10032 —
SUNY Upstate Medical University Hospital Syracuse New York 13210 —
Cincinnati Children's Hospital Medical Center Cincinnati Ohio 45229-3039 —
Oregon Health and Science University Cancer Institute Portland Oregon 97239-3098 —
Children's Hospital of Philadelphia Philadelphia Pennsylvania 19104-9786 —
Children's Hospital of Pittsburgh Pittsburgh Pennsylvania 15213 —
St. Jude Children's Research Hospital Memphis Tennessee 38105 —
Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas Dallas Texas 75390 —
Baylor University Medical Center - Houston Houston Texas 77030-2399 —
Children's Hospital and Regional Medical Center - Seattle Seattle Washington 98105 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00352495, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 13, 2014 · Synced Oct 20, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00352495 live on ClinicalTrials.gov.

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