Stereotactic Radiation Therapy With or Without Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases
Public ClinicalTrials.gov record NCT00377156. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase III Randomized Trial of the Role of Whole Brain Radiation Therapy in Addition to Radiosurgery in Patients With One to Three Cerebral Metastases
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Stereotactic radiation therapy can send x-rays directly to the tumor and cause less damage to normal tissue. Radiation therapy uses high-energy x-rays to kill tumor cells. It is not yet known whether stereotactic radiation therapy is more effective with or without whole-brain radiation therapy in treating patients with brain metastases. PURPOSE: This randomized phase III trial is studying stereotactic radiation therapy and whole-brain radiation therapy to see how well they work compared with stereotactic radiation therapy alone in treating patients with brain metastases.
Study identification
- NCT ID
- NCT00377156
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 213 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 2006 (Actual)
- Primary completion
- Oct 2014 (Actual)
- Completion
- Dec 15, 2019 (Actual)
- Last update posted
- Sep 16, 2022
2006 – 2019
United States locations
- U.S. sites
- 60
- U.S. states
- 27
- U.S. cities
- 53
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Oncology-Deer Valley Center | Phoenix | Arizona | 85027 | — |
| Arizona Oncology Services Foundation | Scottsdale | Arizona | 85260 | — |
| Memorial Medical Center | Modesto | California | 95355 | — |
| Kaiser Permanente - Division of Research - Oakland | Oakland | California | 94611 | — |
| St. Joseph Hospital Regional Cancer Center - Orange | Orange | California | 92868 | — |
| Rohnert Park Cancer Center | Rohnert Park | California | 94928 | — |
| Kaiser Permanente Medical Center - Santa Clara Kiely Campus | Santa Clara | California | 95051 | — |
| Kaiser Permanente Medical Center - Santa Rosa | Santa Rosa | California | 95403 | — |
| University of Colorado Cancer Center at UC Health Sciences Center | Aurora | Colorado | 80045 | — |
| Veterans Affairs Medical Center - Denver | Denver | Colorado | 80220 | — |
| Mayo Clinic - Jacksonville | Jacksonville | Florida | 32224 | — |
| Florida Hospital Cancer Institute at Florida Hospital Orlando | Orlando | Florida | 32803-1273 | — |
| Northside Hospital Cancer Center | Atlanta | Georgia | 30342-1611 | — |
| Saint Joseph's Hospital of Atlanta | Atlanta | Georgia | 30342-1701 | — |
| Northeast Georgia Medical Center | Gainesville | Georgia | 30501 | — |
| Nancy N. and J. C. Lewis Cancer and Research Pavilion at St. Joseph's/Candler | Savannah | Georgia | 31405 | — |
| Saint Alphonsus Cancer Care Center at Saint Alphonsus Regional Medical Center | Boise | Idaho | 83706 | — |
| Northwest Community Hospital | Arlington Heights | Illinois | 60005 | — |
| Via Christi Cancer Center at Via Christi Regional Medical Center | Wichita | Kansas | 67214 | — |
| Lucille P. Markey Cancer Center at University of Kentucky | Lexington | Kentucky | 40536-0093 | — |
| Owensboro Mercy Medical Center | Owensboro | Kentucky | 42303 | — |
| Ochsner Cancer Institute at Ochsner Clinic Foundation | New Orleans | Louisiana | 70121 | — |
| Lowell General Hospital | Lowell | Massachusetts | 01854 | — |
| Saint Vincent Hospital at Worcester Medical Center | Worcester | Massachusetts | 01608 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Josephine Ford Cancer Center at Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| West Michigan Cancer Center | Kalamazoo | Michigan | 49007-3731 | — |
| CCOP - Duluth | Duluth | Minnesota | 55805 | — |
| Mayo Clinic Cancer Center | Rochester | Minnesota | 55905 | — |
| CentraCare Clinic - River Campus | Saint Cloud | Minnesota | 56303 | — |
| Cancer Institute of Cape Girardeau, LLC | Cape Girardeau | Missouri | 63703 | — |
| Saint Luke's Cancer Institute at Saint Luke's Hospital | Kansas City | Missouri | 64111 | — |
| Billings Clinic - Downtown | Billings | Montana | 59107-7000 | — |
| Immanuel Medical Center | Omaha | Nebraska | 68122 | — |
| Seacoast Cancer Center at Wentworth - Douglass Hospital | Dover | New Hampshire | 03820 | — |
| Elliot Regional Cancer Center at Elliot Hospital | Manchester | New Hampshire | 03103 | — |
| Somerset Medical Center | Somerville | New Jersey | 08876 | — |
| J. Phillip Citta Regional Cancer Center at Community Medical Center | Toms River | New Jersey | 08755 | — |
| Carolinas Medical Center/Levine Cancer Institute | Charlotte | North Carolina | 28203 | — |
| Blumenthal Cancer Center at Carolinas Medical Center | Charlotte | North Carolina | 28232-2861 | — |
| Cape Fear Valley Medical Center Cancer Center | Fayetteville | North Carolina | 28302-2000 | — |
| Coastal Carolina Radiation Oncology Center | Wilmington | North Carolina | 28401 | — |
| Forsyth Regional Cancer Center at Forsyth Medical Center | Winston-Salem | North Carolina | 27103 | — |
| Medcenter One Hospital Cancer Care Center | Bismarck | North Dakota | 58501 | — |
| Sanford Bismarck Medical Center | Bismarck | North Dakota | 58501 | — |
| Summa Center for Cancer Care at Akron City Hospital | Akron | Ohio | 44309-2090 | — |
| Cancer Care Center, Incorporated | Salem | Ohio | 44460 | — |
| Cancer Treatment Center | Wooster | Ohio | 44691 | — |
| Legacy Mount Hood Medical Center | Gresham | Oregon | 97030 | — |
| Legacy Good Samaritan Hospital & Comprehensive Cancer Center | Portland | Oregon | 97210 | — |
| Legacy Good Samaritan Hospital and Medical Center | Portland | Oregon | 97210 | — |
| Geisinger Cancer Institute at Geisinger Health | Danville | Pennsylvania | 17822-0001 | — |
| Frankford Hospital Cancer Center - Torresdale Campus | Philadelphia | Pennsylvania | 19114 | — |
| Cancer Centers of the Carolinas - Faris Road | Greenville | South Carolina | 29605 | — |
| CCOP - Greenville | Greenville | South Carolina | 29615 | — |
| Greenville Cancer Center of the Carolinas (CCOP) | Greenville | South Carolina | 29615 | — |
| University of Texas Medical Branch | Galveston | Texas | 77555 | — |
| Legacy Salmon Creek Medical Center | Vancouver | Washington | 98686 | — |
| St. Vincent Hospital Regional Cancer Center | Green Bay | Wisconsin | 54307-3508 | — |
| All Saints Cancer Center at Wheaton Franciscan Healthcare | Racine | Wisconsin | 53405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00377156, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 16, 2022 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00377156 live on ClinicalTrials.gov.