ClinicalTrials.gov record
Completed Phase 3 Interventional Results available

05-001: Treatment of Acute Lymphoblastic Leukemia in Children

ClinicalTrials.gov ID: NCT00400946

Public ClinicalTrials.gov record NCT00400946. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 20, 2026, 6:47 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Treatment of Acute Lymphoblastic Leukemia in Children

Study identification

NCT ID
NCT00400946
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Dana-Farber Cancer Institute
Other
Enrollment
800 participants

Conditions and interventions

Interventions

  • asparaginase Drug
  • cyclophosphamide Drug
  • cytarabine Drug
  • dexamethasone Drug
  • dexrazoxane hydrochloride Drug
  • doxorubicin hydrochloride Drug
  • etoposide Drug
  • leucovorin calcium Drug
  • mercaptopurine Drug
  • methotrexate Drug
  • methylprednisolone Drug
  • pegaspargase Drug
  • prednisolone Drug
  • radiation therapy Radiation
  • therapeutic hydrocortisone Drug
  • vincristine sulfate Drug

Drug · Radiation

Eligibility (public fields only)

Age range
1 Year to 18 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 31, 2005
Primary completion
Jul 31, 2014
Completion
May 31, 2019
Last update posted
Feb 12, 2026

2005 – 2019

United States locations

U.S. sites
5
U.S. states
3
U.S. cities
5
Facility City State ZIP Site status
Dana Farber Cancer Institute Boston Massachusetts 02115
Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center New York New York 10032
James P. Wilmot Cancer Center at University of Rochester Medical Center Rochester New York 14642
Albert Einstein Cancer Center at Albert Einstein College of Medicine The Bronx New York 10461
Hasbro Children's Hospital Providence Rhode Island 02903

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00400946, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 12, 2026 · Synced May 20, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00400946 live on ClinicalTrials.gov.

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