An Efficacy Study Comparing ZD6474 to Placebo in Medullary Thyroid Cancer
Public ClinicalTrials.gov record NCT00410761. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An International, Phase III, Randomized, Double-Blinded, Placebo-Controlled, Multi-Center Study to Assess the Efficacy of ZD6474 (ZACTIMATM) Versus Placebo in Subjects With Unresectable Locally Advanced or Metastatic Medullary Thyroid Cancer
Study identification
- NCT ID
- NCT00410761
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Genzyme, a Sanofi Company
- Industry
- Enrollment
- 331 participants
Conditions and interventions
Conditions
Interventions
- ZD6474 (Vandetanib) Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 22, 2006
- Primary completion
- Jul 30, 2009
- Completion
- Jul 25, 2024
- Last update posted
- Sep 23, 2025
2006 – 2024
United States locations
- U.S. sites
- 32
- U.S. states
- 16
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Investigational Site Number 3 | Little Rock | Arkansas | 72205 | — |
| University Arkansas Site Number : 3 | Little Rock | Arkansas | 72205 | — |
| Investigational Site Number 8 | San Francisco | California | 94115 | — |
| USCF / Mt Zion Medical Center Site Number : 8 | San Francisco | California | 94115 | — |
| Investigational Site Number 9 | Aurora | Colorado | 80010 | — |
| University Of Colorado Health Sciences Center Site Number : 9 | Aurora | Colorado | 80010 | — |
| Investigational Site Number 11 | New Haven | Connecticut | 06510 | — |
| Yale University School Medicine Site Number : 11 | New Haven | Connecticut | 06510 | — |
| Investigational Site Number 15 | Jacksonville | Florida | 32224 | — |
| Mayo Clinic- Site Number : 15 | Jacksonville | Florida | 32224 | — |
| Investigational Site Number 18 | Chicago | Illinois | 60637 | — |
| The University Of Chicago Site Number : 18 | Chicago | Illinois | 60637 | — |
| Investigational Site Number 17 | Lexington | Kentucky | 40536-0298 | — |
| The University Of Kentucky Site Number : 17 | Lexington | Kentucky | 40536-0298 | — |
| Dana Farber Cancer Institute Site Number : 2 | Boston | Massachusetts | 02115 | — |
| Investigational Site Number 2 | Boston | Massachusetts | 02115 | — |
| Investigational Site Number 7 | Detroit | Michigan | 48201 | — |
| Wayne State University / Harper Hospital Site Number : 7 | Detroit | Michigan | 48201 | — |
| Investigational Site Number 14 | Rochester | Minnesota | 55905 | — |
| Mayo Clinic- Site Number : 14 | Rochester | Minnesota | 55905 | — |
| Investigational Site Number 10 | St Louis | Missouri | 63110 | — |
| Washington University School Of Med Site Number : 10 | St Louis | Missouri | 63110 | — |
| Investigational Site Number 6 | Cincinnati | Ohio | 45267-0589 | — |
| University Of Cincinnati Site Number : 6 | Cincinnati | Ohio | 45267-0589 | — |
| Investigational Site Number 22 | Portland | Oregon | 97239 | — |
| Oregon Health & Science University- Site Number : 22 | Portland | Oregon | 97239 | — |
| Investigational Site Number 19 | Charleston | South Carolina | 29425 | — |
| Medical University of South Carolina- Site Number : 19 | Charleston | South Carolina | 29425 | — |
| Anderson Cancer Center Site Number : 13 | Houston | Texas | 77030 | — |
| Investigational Site Number 13 | Houston | Texas | 77030 | — |
| Fletcher Allen Health Care Site Number : 21 | Burlington | Vermont | 05401 | — |
| Investigational Site Number 21 | Burlington | Vermont | 05401 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 95 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00410761, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 23, 2025 · Synced May 18, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00410761 live on ClinicalTrials.gov.