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Completed Phase 2 Interventional Results available

A Study of the Safety and Efficacy of Microplasmin to Induce a Posterior Vitreous Detachment (MIVI III)

ClinicalTrials.gov ID: NCT00412958

Public ClinicalTrials.gov record NCT00412958. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 21, 2026, 11:24 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multicenter, Randomized, Placebo-Controlled, Double-Masked, Parallel Group, Dose-Ranging Clinical Trial of Intravitreal Microplasmin in Patients Undergoing Surgical Vitrectomy: The MIVI III (Microplasmin For Vitreous Injection III) Trial

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

A multicenter study to compare multiple doses of intravitreal microplasmin in patients undergoing surgical vitrectomy.

Study identification

NCT ID
NCT00412958
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
ThromboGenics
Industry
Enrollment
125 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 2006 (Type not available)
Primary completion
Oct 2008 (Actual)
Completion
Oct 2008 (Actual)
Last update posted
Dec 17, 2014

2006 – 2008

United States locations

U.S. sites
20
U.S. states
14
U.S. cities
19
Facility City State ZIP Site status
Retina Centers, P.C. Tucson Arizona 85704 —
VMR Institute Huntington Beach California 92647 —
Jules Stein Eye Institute/UCLA Los Angeles California 90095 —
Retinal Consultants of San Diego Poway California 92064 —
Retinal Consultants Medical Group Sacramento California 95819 —
National Ophtlamic Research Institute Fort Meyers Florida 33912 —
Center for Retina and Macular Disease Winter Haven Florida 33880 —
Rush University Med. Ctr Chicago Illinois 60612 —
Mailing add: New England Eye Center - Tufts Boston Massachusetts 02111 —
Associated Retinal Consultants, P.C. Royal Oak Michigan 48073 —
Vitroretinal Surgery, PA Minneapolis Minnesota 55435 —
Retina Vitreous Centre, PA New Brunswick New Jersey 08901 —
Columbia University - Harkness Eye Institute New York New York 10032 —
Retina Vitreous Surgeons of Central NY New York New York 13224 —
Duke Eye Center Durham North Carolina 27710 —
Retina Association of Cleveland Lakewood Ohio 44107 —
Allegheny Ophthalmic & Orbital Associates, P.C. Pittsburgh Pennsylvania 15212 —
Vanderbilt Eye Institute Nashville Tennessee 37232-8808 —
Vitreoretinal Consultants Houston Texas 77030 —
Valley Retina Institute, P.A. McAllen Texas 78503 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00412958, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 17, 2014 · Synced Oct 21, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00412958 live on ClinicalTrials.gov.

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