A Study of the Safety and Efficacy of Microplasmin to Induce a Posterior Vitreous Detachment (MIVI III)
Public ClinicalTrials.gov record NCT00412958. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Placebo-Controlled, Double-Masked, Parallel Group, Dose-Ranging Clinical Trial of Intravitreal Microplasmin in Patients Undergoing Surgical Vitrectomy: The MIVI III (Microplasmin For Vitreous Injection III) Trial
Study identification
- NCT ID
- NCT00412958
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- ThromboGenics
- Industry
- Enrollment
- 125 participants
Conditions and interventions
Conditions
Interventions
- Ocriplasmin 125µg Drug
- Ocriplasmin 25µg Drug
- Ocriplasmin 75µg Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 30, 2006
- Primary completion
- Sep 30, 2008
- Completion
- Sep 30, 2008
- Last update posted
- Dec 16, 2014
2006 – 2008
United States locations
- U.S. sites
- 20
- U.S. states
- 14
- U.S. cities
- 19
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Retina Centers, P.C. | Tucson | Arizona | 85704 | — |
| VMR Institute | Huntington Beach | California | 92647 | — |
| Jules Stein Eye Institute/UCLA | Los Angeles | California | 90095 | — |
| Retinal Consultants of San Diego | Poway | California | 92064 | — |
| Retinal Consultants Medical Group | Sacramento | California | 95819 | — |
| National Ophtlamic Research Institute | Fort Meyers | Florida | 33912 | — |
| Center for Retina and Macular Disease | Winter Haven | Florida | 33880 | — |
| Rush University Med. Ctr | Chicago | Illinois | 60612 | — |
| Mailing add: New England Eye Center - Tufts | Boston | Massachusetts | 02111 | — |
| Associated Retinal Consultants, P.C. | Royal Oak | Michigan | 48073 | — |
| Vitroretinal Surgery, PA | Minneapolis | Minnesota | 55435 | — |
| Retina Vitreous Centre, PA | New Brunswick | New Jersey | 08901 | — |
| Columbia University - Harkness Eye Institute | New York | New York | 10032 | — |
| Retina Vitreous Surgeons of Central NY | New York | New York | 13224 | — |
| Duke Eye Center | Durham | North Carolina | 27710 | — |
| Retina Association of Cleveland | Lakewood | Ohio | 44107 | — |
| Allegheny Ophthalmic & Orbital Associates, P.C. | Pittsburgh | Pennsylvania | 15212 | — |
| Vanderbilt Eye Institute | Nashville | Tennessee | 37232-8808 | — |
| Vitreoretinal Consultants | Houston | Texas | 77030 | — |
| Valley Retina Institute, P.A. | McAllen | Texas | 78503 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00412958, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 16, 2014 · Synced May 12, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00412958 live on ClinicalTrials.gov.