ClinicalTrials.gov record
A Study of Embeda (Kadian NT, ALO-01) in Subjects With Pain Due to Osteoarthritis of the Hip or Knee
ClinicalTrials.gov ID: NCT00420992
Public ClinicalTrials.gov record NCT00420992. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 3 Efficacy Study of Kadian NT (Morphine Sulfate Plus Naltrexone Hydrochloride Extended-Release) Capsules in Subjects With Moderate to Severe Chronic Pain Due to Osteoarthritis of the Hip or Knee
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the efficacy of Kadian NT (ALO-01) compared with placebo for treating moderate to severe chronic pain over a 12 week period.
Study identification
- NCT ID
- NCT00420992
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 547 participants
Conditions and interventions
Conditions
Interventions
Drug
Eligibility (public fields only)
- Age range
- 21 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 2006 (Type not available)
- Primary completion
- Nov 2007 (Actual)
- Completion
- Nov 2007 (Actual)
- Last update posted
- Sep 20, 2013
2006 – 2007
United States locations
- U.S. sites
- 81
- U.S. states
- 26
- U.S. cities
- 72
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The Birmingham Pain Center | Birmingham | Alabama | 35244 | — |
| Horizon Research Group | Mobile | Alabama | 36608 | — |
| Arizona Center for Clinical Research | Peoria | Arizona | 85383 | — |
| Arizona Research Center, Inc | Phoenix | Arizona | 85023 | — |
| Premiere Pharmaceutical Research, LLC | Tempe | Arizona | 85282 | — |
| Advanced Clinical Research Institute | Anaheim | California | 92801 | — |
| Orange County Clinical Trials | Anaheim | California | 92801 | — |
| STAT-CARE / Crest Clinical Trials | Anaheim | California | 92804 | — |
| Southbay Pharma Research | Buena Park | California | 90620 | — |
| Providence Clinical Res. (C-trials) | Burbank | California | 91505 | — |
| Med Investigators Inc | Fair Oaks | California | 95628 | — |
| Quality of Life Medical Center, LLC | Hawaiian Gardens | California | 90716 | — |
| NervePro Research | Irvine | California | 92618 | — |
| UCSD Pain and Palliative Care | La Jolla | California | 92093 | — |
| USCD Pain and Palliative Care | La Jolla | California | 92093 | — |
| Private Practice | Pico Rivera | California | 90660 | — |
| Pain Institute of Santa Monica | Santa Monica | California | 90404 | — |
| Boling Clinical Trials | Upland | California | 91786 | — |
| Mountain View Clinical Research, Inc | Denver | Colorado | 80209 | — |
| Stamford Therapeutics Consortium | Stamford | Connecticut | 06905 | — |
| New England Research Associates, LLC | Trumbull | Connecticut | 06611 | — |
| MD Clinical | Hallandale | Florida | 33009 | — |
| Eastern Research | Hialeah | Florida | 33013 | — |
| Florida Institute of Medical Research | Jacksonville | Florida | 32257 | — |
| Drug Study Institiute | Jupiter | Florida | 33458 | — |
| FPA Clinical Research | Kissimmee | Florida | 34741 | — |
| Innovative Research of West Florida | Largo | Florida | 33770 | — |
| Pharmaceutical Research Associates Inc | Merritt Island | Florida | 32953 | — |
| Ormond Medical Arts - Pharmaceutical Research Center | Ormond Beach | Florida | 32174 | — |
| University Clinical Research, Inc | Pembroke Pines | Florida | 33024 | — |
| Coastal Medical Research | Port Orange | Florida | 32127 | — |
| Stedman Clinical Trials | Tampa | Florida | 33613 | — |
| Gold Coast Research LLC | Weston | Florida | 33331 | — |
| River Birch Research Alliance | Blue Ridge | Georgia | 30513 | — |
| Best Clinical Research | Decatur | Georgia | 30034 | — |
| Non-Surgical Orthopaedic and Spine Center | Marietta | Georgia | 30060 | — |
| Drug Studies America | Marietta | Georgia | 30066 | — |
| Northwest Clinical Trials | Boise | Idaho | 83704 | — |
| Research Associates of Central Illinois | Peoria | Illinois | 61614 | — |
| MediSphere Medical Research Center, LLC | Evansville | Indiana | 47714 | — |
| Welborn Clinic | Newburgh | Indiana | 47630 | — |
| International Clinical Research Institute, Inc | Overland Park | Kansas | 66211 | — |
| Clinical Trials Management, LLC | Mandeville | Louisiana | 70471 | — |
| Lousiana Research Associates Inc. | New Orleans | Louisiana | 70114 | — |
| Internal Research Center | Towson | Maryland | 21286 | — |
| Phase III Clinical Research | Fall River | Massachusetts | 02720 | — |
| Northeast Medical Research Associates, Inc | No Dartmouth | Massachusetts | 02747 | — |
| FutureCare Studies | Springfield | Massachusetts | 01107 | — |
| Synergy Medical Education Alliance | Saginaw | Michigan | 48602 | — |
| Medex Healthcare Research Inc | St Louis | Missouri | 63117 | — |
| Lovelace Scientific | Henderson | Nevada | 89014 | — |
| Advanced Biomedical Research of America | Las Vegas | Nevada | 89123 | — |
| Partners in Primary Care | Voorhees Township | New Jersey | 08043 | — |
| Elkind Headache Center | Mount Vernon | New York | 10550 | — |
| The Arthritis Clinic and Carolina Bone and Joint | Charlotte | North Carolina | 28210 | — |
| The Center for Clinical Research, LLC | Winston-Salem | North Carolina | 27103 | — |
| Community Research | Cincinnati | Ohio | 45227 | — |
| Community Research | Cincinnati | Ohio | 45245 | — |
| Clinical Research Source, Inc | Toledo | Ohio | 43551 | — |
| COR Clinical Research | Oklahoma City | Oklahoma | 73103 | — |
| Health Research Institute | Oklahoma City | Oklahoma | 73109 | — |
| Cutting Edge Research | Oklahoma City | Oklahoma | 73116 | — |
| Tulsa Clinical Research | Tulsa | Oklahoma | 74101 | — |
| LVH Neurosciences and Pain Research | Allentown | Pennsylvania | 18103 | — |
| Pennsylvania Research Institute | Bensalem | Pennsylvania | 19020 | — |
| Altoona Center for Clinical Research | Duncansville | Pennsylvania | 16635 | — |
| Commonwealth Primary Care / Fleetwood Clinical Research | Fleetwood | Pennsylvania | 19522 | — |
| Pivotal Clinical Research, LLC | Souderton | Pennsylvania | 18964 | — |
| Tipton Medical and Diagnostic Center | Tipton | Pennsylvania | 16684 | — |
| Premier Medical Group | Clarksville | Tennessee | 37043 | — |
| SCRI | Cordova | Tennessee | 38018 | — |
| Comprehensive Pain Specialists | Hendersonville | Tennessee | 37075 | — |
| SCRI | Memphis | Tennessee | 38119 | — |
| Integrity Clinical Research, LLC | Milan | Tennessee | 38358 | — |
| Walter F. Chase, MD, PA | Austin | Texas | 78705 | — |
| InSite Clinical Research | DeSoto | Texas | 75115 | — |
| Team Research of Central Texas | Killeen | Texas | 76543 | — |
| Radiant Research, San Antonio Northeast | San Antonio | Texas | 78217 | — |
| North San Antonio Healthcare Associates | San Antonio | Texas | 78218 | — |
| Progressive Clinical Research | San Antonio | Texas | 78229 | — |
| HypotheTest, LLC | Roanoke | Virginia | 24018 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00420992, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 20, 2013 · Synced Oct 26, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00420992 live on ClinicalTrials.gov.