Study of Daptomycin in Subjects Undergoing Surgery for Osteomyelitis Associated With an Infected Prosthetic Caused by Staphylococci
Public ClinicalTrials.gov record NCT00428844. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2 Randomized Study Investigating the Safety, Efficacy and Pharmacokinetics of Daptomycin 6 mg/kg and 8 mg/kg Versus Comparator in the Treatment of Subjects Undergoing Surgical Standard of Care for Osteomyelitis Associated With an Infected Prosthetic Hip or Knee Joint Caused by Staphylococci
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a research study designed to look at the efficacy and safety of daptomycin given at a dose of 6 mg/kg or 8 mg/kg in subjects being treated for prosthetic hip or knee infections caused by Staphylococci. These types of bacteria are among the most common types of bacteria causing infections of prosthetic joints.
Study identification
- NCT ID
- NCT00428844
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
- Industry
- Enrollment
- 75 participants
Conditions and interventions
Conditions
Interventions
- daptomycin Drug
- vancomycin Drug
- teicoplanin Drug
- nafcillin Drug
- oxacillin Drug
- flucloxacillin Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 26, 2007 (Actual)
- Primary completion
- Mar 26, 2010 (Actual)
- Completion
- Jun 23, 2010 (Actual)
- Last update posted
- Jan 31, 2018
2007 – 2010
United States locations
- U.S. sites
- 17
- U.S. states
- 13
- U.S. cities
- 17
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UAMS College of Medicine | Little Rock | Arkansas | 72205-7199 | — |
| South Denver Infectious Disease Associates, PC | Englewood | Colorado | 80133 | — |
| Kane and Davis Associates | Washington D.C. | District of Columbia | 20016 | — |
| Infectious Disease Association of Tampa Bay | Tampa | Florida | 33606 | — |
| Idaho Falls Infectious Diseases, PLLC | Idaho Falls | Idaho | 83404 | — |
| Rush St. Luke's Medical Center | Chicago | Illinois | 60612 | — |
| Southern Illinois University School of Medicine | Springfield | Illinois | 62794 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Sierra Infectious Disease | Reno | Nevada | 89502 | — |
| Dartmouth-Hitchcock Medical center | Lebanon | New Hampshire | 03756 | — |
| Wake Forest University Health Sciences | Winston-Salem | North Carolina | 27157 | — |
| Summa Health Systems | Akron | Ohio | 44304 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| Regional Infectious Diseases-Infusion Center | Lima | Ohio | 45801 | — |
| Lehigh Valley Hospital Trauma and Critical Care Research | Allentown | Pennsylvania | 18103 | — |
| Rothman Institute | Philadelphia | Pennsylvania | 19107 | — |
| Gundersen Clinic, LTD | La Crosse | Wisconsin | 54601 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 9 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00428844, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 31, 2018 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00428844 live on ClinicalTrials.gov.