Low-dose Hormone Therapy for Relief of Vasomotor Symptoms
Public ClinicalTrials.gov record NCT00446199. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Double-Blind, Randomized, Placebo-Controlled Study to Determine the Lowest Effective Dose of Combinations of Oral Drospirenone and 17 Beta-Estradiol for the Relief of Moderate to Severe Vasomotor Symptoms in Postmenopausal Women Over a Treatment Period of 12 Weeks
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine the lowest effective dose of the study drug for the relief of moderate to severe vasomotor symptoms in postmenopausal women for 12 weeks.
Study identification
- NCT ID
- NCT00446199
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 735 participants
Conditions and interventions
Conditions
Interventions
- 0.5mg DRSP / 0.5mg E2 (BAY86-4891) Drug
- 0.25mg DRSP / 0.5mg E2 (BAY86-4891) Drug
- Estradiol (E2 0.3mg) Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 40 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 2007 (Type not available)
- Primary completion
- Oct 2008 (Actual)
- Completion
- Nov 2008 (Actual)
- Last update posted
- May 6, 2015
2007 – 2008
United States locations
- U.S. sites
- 76
- U.S. states
- 33
- U.S. cities
- 67
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Mobile | Alabama | 36608 | — |
| Not listed | Chandler | Arizona | 85225 | — |
| Not listed | Phoenix | Arizona | 85031 | — |
| Not listed | Tucson | Arizona | 85712 | — |
| Not listed | Tucson | Arizona | 85741 | — |
| Not listed | Little Rock | Arkansas | 72205 | — |
| Not listed | Paramount | California | 90723 | — |
| Not listed | San Diego | California | 92103 | — |
| Not listed | San Diego | California | 92108 | — |
| Not listed | San Diego | California | 92121 | — |
| Not listed | San Diego | California | 92123 | — |
| Not listed | Valley Village | California | 91607 | — |
| Not listed | Vista | California | 92083 | — |
| Not listed | Colorado Springs | Colorado | 80910 | — |
| Not listed | Denver | Colorado | 80218 | — |
| Not listed | New Britain | Connecticut | 06050 | — |
| Not listed | Boynton Beach | Florida | 33437 | — |
| Not listed | Clearwater | Florida | 33761 | — |
| Not listed | Daytona Beach | Florida | 32114 | — |
| Not listed | Fort Myers | Florida | 33916 | — |
| Not listed | Jacksonville | Florida | 32216 | — |
| Not listed | Lake Worth | Florida | 33461 | — |
| Not listed | Leesburg | Florida | 34748 | — |
| Not listed | Miami | Florida | 33169 | — |
| Not listed | Miami | Florida | 33186 | — |
| Not listed | New Port Richey | Florida | 34655 | — |
| Not listed | Tampa | Florida | 33607 | — |
| Not listed | West Palm Beach | Florida | 33409 | — |
| Not listed | Atlanta | Georgia | 30328 | — |
| Not listed | Atlanta | Georgia | 30342 | — |
| Not listed | Decatur | Georgia | 30034 | — |
| Not listed | Boise | Idaho | 83702 | — |
| Not listed | Idaho Falls | Idaho | 83404 | — |
| Not listed | Arlington Heights | Illinois | 60004 | — |
| Not listed | Champaign | Illinois | 61820 | — |
| Not listed | La Grange Park | Illinois | 60526 | — |
| Not listed | Newburgh | Indiana | 47630 | — |
| Not listed | Lexington | Kentucky | 40536 | — |
| Not listed | Amite | Louisiana | 70422 | — |
| Not listed | Marrero | Louisiana | 70072 | — |
| Not listed | Paw Paw | Michigan | 49079 | — |
| Not listed | Chaska | Minnesota | 55318 | — |
| Not listed | Springfield | Missouri | 65802 | — |
| Not listed | Billings | Montana | 59101 | — |
| Not listed | Billings | Montana | 59102 | — |
| Not listed | Lincoln | Nebraska | 68510 | — |
| Not listed | Las Vegas | Nevada | 89104 | — |
| Not listed | Reno | Nevada | 89502 | — |
| Not listed | Lawrenceville | New Jersey | 08648 | — |
| Not listed | New Brunswick | New Jersey | 08901 | — |
| Not listed | Princeton | New Jersey | 08540 | — |
| Not listed | Albuquerque | New Mexico | 87102 | — |
| Not listed | Raleigh | North Carolina | 27612 | — |
| Not listed | Winston-Salem | North Carolina | 27103 | — |
| Not listed | Fargo | North Dakota | 58105 | — |
| Not listed | Cleveland | Ohio | 44122 | — |
| Not listed | Columbus | Ohio | 43213 | — |
| Not listed | Oklahoma City | Oklahoma | 73103 | — |
| Not listed | Tulsa | Oklahoma | 74105 | — |
| Not listed | Erie | Pennsylvania | 16502 | — |
| Not listed | Philadelphia | Pennsylvania | 19114 | — |
| Not listed | Pittsburgh | Pennsylvania | 15206 | — |
| Not listed | Wexford | Pennsylvania | 15090 | — |
| Not listed | Columbia | South Carolina | 29201 | — |
| Not listed | Sioux Falls | South Dakota | 57105 | — |
| Not listed | Chattanooga | Tennessee | 37403 | — |
| Not listed | Chattanooga | Tennessee | 37404 | — |
| Not listed | Memphis | Tennessee | 38120 | — |
| Not listed | Dallas | Texas | 75234 | — |
| Not listed | Houston | Texas | 77004 | — |
| Not listed | Houston | Texas | 77030 | — |
| Not listed | Burlington | Vermont | 05401 | — |
| Not listed | Norfolk | Virginia | 23507 | — |
| Not listed | Richmond | Virginia | 23294 | — |
| Not listed | Renton | Washington | 98055 | — |
| Not listed | Seattle | Washington | 98105 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00446199, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 6, 2015 · Synced Oct 30, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00446199 live on ClinicalTrials.gov.