Randomized, Double-blind, Dose-range-finding, Phase 2 Study of Linaclotide Administered to Patients With Irritable Bowel Syndrome With Constipation (IBS-C)
Public ClinicalTrials.gov record NCT00460811. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Multicenter, Double-blind, Placebo-controlled, Dose-range-finding, Parallel-design, Phase 2 Trial of Oral Linaclotide Acetate Administered to Patients With Irritable Bowel Syndrome With Constipation
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine the safety, efficacy, and dose response of a range of oral doses of linaclotide administered to patients meeting criteria for IBS-C.
Study identification
- NCT ID
- NCT00460811
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 420 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 2007 (Type not available)
- Primary completion
- Feb 2008 (Actual)
- Completion
- Apr 2008 (Actual)
- Last update posted
- Feb 4, 2013
2007 – 2008
United States locations
- U.S. sites
- 79
- U.S. states
- 32
- U.S. cities
- 79
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Microbia Investigational Site | Huntsville | Alabama | 35801 | — |
| Microbia Investigational Site | Chandler | Arizona | — | — |
| Microbia Investigational Site | Tuscon | Arizona | — | — |
| Microbia Investigational Site | Sherwood | Arkansas | — | — |
| Microbia Investigational Site | Anaheim | California | — | — |
| Microbia Investigational Site | Garden Grove | California | — | — |
| Microbia Investigational Site | Sacramento | California | — | — |
| Microbia Investigational Site | San Diego | California | — | — |
| Microbia Investigational Site | Bristol | Connecticut | — | — |
| Microbia Investigational Site | Boynton Beach | Florida | — | — |
| Microbia Investigational Site | Dunedin | Florida | — | — |
| Microbia Investigational Site | Largo | Florida | — | — |
| Microbia Investigational Site | Ocala | Florida | — | — |
| Microbia Investigational Site | Port Orange | Florida | — | — |
| Microbia Investigational Site | Stuart | Florida | — | — |
| Microbia Investigational Site | Tampa | Florida | 33607 | — |
| Microbia Investigational Site | Stockbridge | Georgia | — | — |
| Microbia Investigational Site | Libertyville | Illinois | — | — |
| Microbia Investigational Site | Peoria | Illinois | 60601 | — |
| Microbia Investigational Site | Clive | Iowa | — | — |
| Microbia Investigational Site | Davenport | Iowa | — | — |
| Microbia Investigational Site | Mission | Kansas | — | — |
| Microbia Investigational Site | Shawnee | Kansas | — | — |
| Microbia Investigational Site | Baton Rouge | Louisiana | — | — |
| Microbia Investigational Site | Monroe | Louisiana | 71201 | — |
| Microbia Investigational Site | West Monroe | Louisiana | — | — |
| Microbia Investigational Site | Annapolis | Maryland | — | — |
| Microbia Investigational Site | Silver Spring | Maryland | — | — |
| Microbia Investigational Site | Fall River | Massachusetts | — | — |
| Microbia Investigational Site | Ann Arbor | Michigan | — | — |
| Microbia Investigational Site | St Louis | Missouri | — | — |
| Microbia Investigational Site | Missoula | Montana | — | — |
| Microbia Investigational Site | Henderson | Nevada | — | — |
| Microbia Investigational Site | Las Vegas | Nevada | — | — |
| Microbia Investigational Site | Blackwood | New Jersey | — | — |
| Microbia Investigational Site | Great Neck | New York | 11020 | — |
| Microbia Investigational Site | Pittsford | New York | — | — |
| Microbia Investigational Site | Asheville | North Carolina | — | — |
| Microbia Investigational Site | Chapel Hill | North Carolina | — | — |
| Microbia Investigational Site | Elkin | North Carolina | — | — |
| Microbia Investigational Site | Greensboro | North Carolina | — | — |
| Microbia Investigational Site | Harrisburg | North Carolina | — | — |
| Microbia Investigational Site | Hickory | North Carolina | — | — |
| Microbia Investigational Site | Raleigh | North Carolina | — | — |
| Microbia Investigational Site | Statesville | North Carolina | — | — |
| Microbia Investigational Site | Winston-Salem | North Carolina | — | — |
| Microbia Investigational Site | Cincinnati | Ohio | — | — |
| Microbia Investigational Site | Cleveland | Ohio | — | — |
| Microbia Investigational Site | Dayton | Ohio | — | — |
| Microbia Investigational Site | Sylvania | Ohio | — | — |
| Microbia Investigational Site | Oklahoma City | Oklahoma | — | — |
| Microbia Investigational Site | Tulsa | Oklahoma | — | — |
| Microbia Investigational Site | Yukon | Oklahoma | — | — |
| Microbia Investigational Site | Medford | Oregon | — | — |
| Microbia Investigational Site | Levittown | Pennsylvania | — | — |
| Microbia Investigational Site | Pittsburgh | Pennsylvania | — | — |
| Microbia Investigational Site | Reading | Pennsylvania | — | — |
| Microbia Investigational Site | Sellersville | Pennsylvania | 18960 | — |
| Microbia Investigational Site | Anderson | South Carolina | — | — |
| Microbia Investigational Site | Mt. Pleasant | South Carolina | — | — |
| Microbia Investigational Site | Simpsonville | South Carolina | — | — |
| Microbia Investigational Site | Summerville | South Carolina | — | — |
| Microbia Investigational Site | Bristol | Tennessee | — | — |
| Microbia Investigational Site | Germantown | Tennessee | — | — |
| Microbia Investigational Site | Jackson | Tennessee | — | — |
| Microbia Investigational Site | Kingsport | Tennessee | — | — |
| Microbia Investigational Site | Beaumont | Texas | — | — |
| Microbia Investigational Site | Corsicana | Texas | — | — |
| Microbia Investigational Site | El Paso | Texas | — | — |
| Microbia Investigational Site | San Antonio | Texas | — | — |
| Microbia Investigational Site | Ogden | Utah | — | — |
| Microbia Investigational Site | Chesapeake | Virginia | — | — |
| Microbia Investigational Site | Lynchburg | Virginia | — | — |
| Microbia Investigational Site | Richmond | Virginia | — | — |
| Microbia Investigational Site | Lakewood | Washington | — | — |
| Microbia Investigational Site | Olympia | Washington | — | — |
| Microbia Investigational Site | Vancouver | Washington | — | — |
| Microbia Investigational Site | Charleston | West Virginia | — | — |
| Microbia Investigational Site | La Crosse | Wisconsin | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 6 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00460811, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 4, 2013 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00460811 live on ClinicalTrials.gov.