Efficacy and Safety of AEB071 Versus Tacrolimus in Combination With Mycophenolate Acid Sodium, Basiliximab and Steroids in Preventing Acute Rejection After Kidney Transplantation
Public ClinicalTrials.gov record NCT00492869. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A 12-month Open-label, Randomized, Multicenter, Sequential Cohort, Dose Finding Study to Evaluate the Efficacy, Safety and Tolerability of Oral AEB071 Versus Tacrolimus in Combination With Mycophenolate Acid Sodium, Basiliximab and Corticosteroids in de Novo Adult Renal Transplant Recipients
Study identification
- NCT ID
- NCT00492869
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Enrollment
- 124 participants
Conditions and interventions
Conditions
Interventions
- AEB071 Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 31, 2006
- Primary completion
- Apr 30, 2008
- Completion
- Not listed
- Last update posted
- Dec 21, 2020
Started 2007
United States locations
- U.S. sites
- 23
- U.S. states
- 14
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| USC Medical Center | Los Angeles | California | 90033 | — |
| University of California San Diego | San Diego | California | 92103-8401 | — |
| California Pacific Medical Center | San Francisco | California | 94115 | — |
| UCSF | San Francisco | California | 94143 | — |
| University of Colorado Health Science Center | Denver | Colorado | 80262 | — |
| Lifelink, Inc. | Tampa | Florida | — | — |
| U of Maryland Medical Center | Baltimore | Maryland | — | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | — | — |
| Brigham and Women's Hospital | Boston | Massachusetts | — | — |
| University of Michigan Health System | Ann Arbor | Michigan | — | — |
| Henry Ford Hospital Transplant Institute | Detroit | Michigan | — | — |
| Saint Barnabas Medical Center | Livingston | New Jersey | 07039 | — |
| Mount Sinai Medical Center | New York | New York | 10029 | — |
| Comprehensive Transplant Clinic | New York | New York | — | — |
| Duke University Medical Center | Durham | North Carolina | — | — |
| University of Cincinnati, Dept of Internal Medicine | Cincinnati | Ohio | — | — |
| University of Toledo Health Science Campus | Toledo | Ohio | — | — |
| University of Pennsylvania Health System-Presbyterian Medical Center | Philadelphia | Pennsylvania | 19104 | — |
| Baylor U Medical Center | Dallas | Texas | — | — |
| University of Texas Medical Branch at Galveston | Galveston | Texas | 77555 - 0561 | — |
| University of Utah | Salt Lake City | Utah | — | — |
| U of Wisconsin Hospital Clinics | Madison | Wisconsin | — | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 18 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00492869, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 21, 2020 · Synced May 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00492869 live on ClinicalTrials.gov.