Zileuton to Treat Adults With Chronic Obstructive Pulmonary Disease (The LEUKO Study)
Public ClinicalTrials.gov record NCT00493974. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Antileukotriene Therapy for COPD Exacerbations
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Chronic obstructive pulmonary disease (COPD) is a long-term lung disease that is caused by cigarette smoking or by breathing in other lung irritants, including pollution, dust, or chemicals. The purpose of this study is to evaluate the effectiveness of zileuton, a medication that is used to control asthma symptoms, at reducing the length of a hospital stay for adults who are hospitalized for a COPD exacerbation, or worsening of COPD symptoms.
Study identification
- NCT ID
- NCT00493974
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 119 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 45 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 2007 (Type not available)
- Primary completion
- Dec 2008 (Actual)
- Completion
- Dec 2008 (Actual)
- Last update posted
- Nov 18, 2019
2007 – 2008
United States locations
- U.S. sites
- 18
- U.S. states
- 8
- U.S. cities
- 11
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama Lung Health Center | Birmingham | Alabama | 35249 | — |
| Veteran's Administration Medical Center | Birmingham | Alabama | 35294 | — |
| LA BioMed at Harbor, University of California | Los Angeles | California | 90502 | — |
| University of California San Francisco-Airway Clinical Research Center | San Francisco | California | 94143 | — |
| Denver Health Medical Center | Denver | Colorado | 80204 | — |
| National Jewish Medical and Research Center | Denver | Colorado | 80206 | — |
| Veteran's Administration Medical Center | Denver | Colorado | 80220 | — |
| University of Maryland Hospital | Baltimore | Maryland | 21201 | — |
| Fallon Clinic | Boston | Massachusetts | 01605 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Veteran's Administration Medical Center | Boston | Massachusetts | 02132 | — |
| Veteran's Administration Medical Center | Ann Arbor | Michigan | 48105 | — |
| University of Michigan Medical Center | Ann Arbor | Michigan | 48109 | — |
| Veteran's Administration Medical Center | Minneapolis | Minnesota | 55417 | — |
| HealthPartners Research Foundation | Minneapolis | Minnesota | 55440 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Temple University Lung Center | Philadelphia | Pennsylvania | 19140 | — |
| University of Pittsburgh Emphysema Research Center | Pittsburgh | Pennsylvania | 15213 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00493974, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 18, 2019 · Synced Oct 26, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00493974 live on ClinicalTrials.gov.