Efficacy and Safety of Armodafinil for Adults With Excessive Sleepiness Obstructive Sleep Apnea/Hypopnea and Depression
Public ClinicalTrials.gov record NCT00518986. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Double-Blind, Placebo-Controlled, Study to Evaluate the Efficacy and Safety of Armodafinil for Adults With Excessive Sleepiness Associated With Obstructive Sleep Apnea/Hypopnea Syndrome With Major Depressive Disorder or Dysthymic Disorder
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective of the study is to evaluate whether armodafinil at a target dosage of 200 mg/day is more effective than placebo treatment in improving excessive sleepiness in patients with obstructive sleep apnea/hypopnea syndrome (OSAHS) who have comorbid major depressive disorder or dysthymic disorder.
Study identification
- NCT ID
- NCT00518986
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 249 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 2007 (Type not available)
- Primary completion
- Mar 2009 (Actual)
- Completion
- Mar 2009 (Actual)
- Last update posted
- Jul 19, 2013
2007 – 2009
United States locations
- U.S. sites
- 62
- U.S. states
- 26
- U.S. cities
- 53
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Jasper Summit Research, LLC | Jasper | Alabama | 35501 | — |
| Pulmonary Associates, P.A. | Phoenix | Arizona | 85012 | — |
| Psypharma Clinical Research | Phoenix | Arizona | 85050 | — |
| PsyPharm Clinical Research, Inc. | Tucson | Arizona | 85712 | — |
| Behavioral Research Specialists | Glendale | California | 91204 | — |
| California Clinical Trials Medical Group, Inc. | Glendale | California | 91206 | — |
| Pacific Sleep Medicine Services, Inc. | Redlands | California | 92373 | — |
| Pacific Research Network, Inc. | San Diego | California | 92103 | — |
| Pacific Sleep Medicine Services, Inc. | San Diego | California | 92121 | — |
| California Clinical Trials Medical Group, Inc. | San Diego | California | 92123 | — |
| SDS Clinical Research | Santa Ana | California | 92704 | — |
| St. Johns Medical Plaza Sleep Disorders Center | Santa Monica | California | 90404 | — |
| National Jewish Medical and Research Center | Denver | Colorado | 80206 | — |
| Rocky Mountain Center for Clinical Research | Wheat Ridge | Colorado | 80033 | — |
| PAB Clinical Research | Brandon | Florida | 33511 | — |
| Florida Sleep Institute | Spring Hill | Florida | 34609 | — |
| Clinical Research Group of St. Petersburg | St. Petersburg | Florida | 33707 | — |
| SomnoMedics | Tampa | Florida | 33607 | — |
| Stedman Clinical Trials, LLC | Tampa | Florida | 33613 | — |
| Florida Pulmonary Research Center, LLC | Winter Park | Florida | 33613 | — |
| The Sleep Disorders Center | Atlanta | Georgia | 30339 | — |
| Neurotrials Research, Inc | Atlanta | Georgia | 30342 | — |
| Sleep Disorders Center of Georgia | Atlanta | Georgia | 30342 | — |
| SleepMed, Inc | Macon | Georgia | 31201 | — |
| Chicago Research Center | Chicago | Illinois | 60634 | — |
| Peoria Pulmonary Associates | Peoria | Illinois | 61603 | — |
| Sleep and Behavior Medicine | Vernon Hills | Illinois | 60061 | — |
| The Center for Sleep and Wake Disorders | Danville | Indiana | 46122 | — |
| Vince & Associates Clinical Research | Overland Park | Kansas | 66212 | — |
| Graves Gilbert Clinic | Bowling Green | Kentucky | 42101 | — |
| Community Research | Crestview | Kentucky | 45217 | — |
| Clinical Trials of America | Shreveport | Louisiana | 71101 | — |
| The Center for Sleep & Wake Disorders | Chevy Chase | Maryland | 20815 | — |
| Sleep Health Centers | Brighton | Massachusetts | 02135 | — |
| AccelRx Research | Fall River | Massachusetts | 02721 | — |
| The Center for Sleep Medicine | Hattiesburg | Mississippi | 39406 | — |
| Washington University | St Louis | Missouri | 63108 | — |
| Somnos Sleep Center | Lincoln | Nebraska | 68510 | — |
| Brooklyn Medical Institute | Brooklyn | New York | 11223 | — |
| Clinilabs, Inc | New York | New York | 10019 | — |
| Sleep Medicine Centers | West Seneca | New York | 14224 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Clinical Trials of America | Hickory | North Carolina | 28601 | — |
| Tri-State Sleep Disorders Center | Cincinnati | Ohio | 45246 | — |
| Ohio Sleep Medicine Institute | Dublin | Ohio | 43017 | — |
| North Star Medical Research, LLC | Middleburg Heights | Ohio | 44130 | — |
| St. Vincent Mercy Medical Center | Toledo | Ohio | 43606 | — |
| Lynn Health Science Institute | Oklahoma City | Oklahoma | 73112 | — |
| Sleep Lab of Northeastern PA | Clarks Summit | Pennsylvania | 18411 | — |
| University of Pennsylvania Center for Sleep | Philadelphia | Pennsylvania | 19104 | — |
| CRI Worldwide | Philadelphia | Pennsylvania | 19139 | — |
| University Services | West Chester | Pennsylvania | 19380 | — |
| AccelRx Research | Lincoln | Rhode Island | 02865 | — |
| Lowcountry Lung and Critical Care | Charleston | South Carolina | 29406 | — |
| SleepMed of South Carolina | Columbia | South Carolina | 29201 | — |
| Sleep Medicine of Middle Tennessee | Nashville | Tennessee | 37203 | — |
| FutureSearch Trials of Neurology | Austin | Texas | 78756 | — |
| Sleep Medicine Associates of Texas, P.A. | Dallas | Texas | 75231 | — |
| Baylor College of Medicine VAMC Sleep Research | Houston | Texas | 77030 | — |
| Houston Sleep Center | Houston | Texas | 77063 | — |
| Northwest Clinical Research | Bellevue | Washington | 98004 | — |
| Pacific Sleep Medicine Services, Inc. | Seattle | Washington | 98122 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00518986, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 19, 2013 · Synced Oct 26, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00518986 live on ClinicalTrials.gov.