Nilotinib vs Imatinib in Adult Patients With Philadelphia (Ph+) Chronic Myelogenous Leukemia in Chronic Phase (CML-CP)
Public ClinicalTrials.gov record NCT00519090. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III Randomized, Open- Label Multi-center Study of Nilotinib Versus Imatinib in Adult Patients With Ph+ Chronic Myelogenous Leukemia in Chronic Phase (CML-CP) Who Have a Suboptimal Cytogenetic Response (CyR) on Imatinib
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
In this study, the efficacy and safety of nilotinib 400 mg twice daily, will be compared with imatinib 400 mg twice daily in patients with a suboptimal response to imatinib for their Philadelphia chromosome-positive (Ph+) Chronic Myelogenous Leukemia in the chronic phase (CML-CP).
Study identification
- NCT ID
- NCT00519090
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 6 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 2007 (Type not available)
- Primary completion
- Oct 2008 (Actual)
- Completion
- Oct 2008 (Actual)
- Last update posted
- Nov 7, 2011
2007 – 2008
United States locations
- U.S. sites
- 36
- U.S. states
- 16
- U.S. cities
- 35
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Cancer Center | Tucson | Arizona | 85701 | — |
| Southern California Permanente Medical Group | Anaheim | California | 92801 | — |
| Southern California Permanente Medical Group | Baldwin Park | California | 91706 | — |
| Southern California Permanente Medical Group | Fontana | California | 92334 | — |
| Kaiser Permanente Medical Group/Hayward Medical Center | Hayward | California | 94540 | — |
| Southern California Permanente Medical Group | Los Angeles | California | 90001 | — |
| Kaiser Permanente Medical Group/Oakland Medical Center | Oakland | California | 94601 | — |
| Southern California Permanente Medical Group | Panorama City | California | 91402 | — |
| Southern California Permanente Medical Group | Riverside | California | 92501 | — |
| Kaiser Permanente Medical Group/Sacramento Medical Center | Sacramento | California | 94203 | — |
| Southern California Permanente Medical Group | San Diego | California | 92101 | — |
| Kaiser Permanente Medical Group | San Francisco | California | 94101 | — |
| Kaiser Permanente Medical Group | San Jose | California | 95101 | — |
| Kaiser Permanente Medical Group/Santa Clara Medical Office | Santa Clara | California | 95050 | — |
| Kaiser Permanente Medical Group/South San Francisco Medical Center | South San Francisco | California | 94101 | — |
| Kaiser Permanente Medical Group/Vallejo Medical Center | Vallejo | California | 94589 | — |
| Kaiser Permanente Medical Group/Walnut Creek Medical Center | Walnut Creek | California | 94595 | — |
| Southen California Permanente Medical Group | Woodland Hills | California | 91364 | — |
| Rocky Mountain Cancer Center | Denver | Colorado | 80201 | — |
| Northwestern Memorial Hospital | Chicago | Illinois | 60601 | — |
| The University of Chicago Medical Center | Chicago | Illinois | 60601 | — |
| Indiana Blood and Marrow Transplantation | Beech Grove | Indiana | 46107 | — |
| Holden Cancer Center | Iowa City | Iowa | 52240 | — |
| Johns Hopkins Hospital | Baltimore | Maryland | 21201 | — |
| University of Michigan | Ann Arbor | Michigan | 48103 | — |
| Hematology Centers of Western Michigan | Grand Rapids | Michigan | 49501 | — |
| Methodist Cancer Center | Omaha | Nebraska | 68101 | — |
| The Cancer Center at Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Duke University Hospital | Durham | North Carolina | 27701 | — |
| Wake Forest University Health Sciences | Winston-Salem | North Carolina | 27101 | — |
| Oregon Health Sciences University | Portland | Oregon | 97201 | — |
| St. Luke's Hospital and Health Network | Bethlehem | Pennsylvania | 18015 | — |
| Jones Cancer Center | Germantown | Tennessee | 38138 | — |
| Vanderbilt University | Nashville | Tennessee | 37201 | — |
| University of Texas/MD Anderson Cancer Center | Houston | Texas | 77001 | — |
| Swedish Cancer Institute | Seattle | Washington | 98101 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 44 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00519090, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 7, 2011 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00519090 live on ClinicalTrials.gov.