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Completed Phase 2 Interventional Results available

A Trial to Evaluate the Safety and Efficacy of PS433540 to Treat Hypertension

ClinicalTrials.gov ID: NCT00522925

Public ClinicalTrials.gov record NCT00522925. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 27, 2026, 3:55 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Prospective, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Safety and Efficacy of a Novel Dual Angiotensin and Endothelin Receptor Antagonist (PS433540) in Subjects With Stage I and II Hypertension

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of the study is to see if PS433540 lowers blood pressure better than placebo and to see how safe PS433540 is compared to placebo.

Study identification

NCT ID
NCT00522925
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Ligand Pharmaceuticals
Industry
Enrollment
280 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
30 Years to 80 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 2007 (Type not available)
Primary completion
Apr 2008 (Actual)
Completion
May 2008 (Actual)
Last update posted
Sep 16, 2011

2007 – 2008

United States locations

U.S. sites
15
U.S. states
8
U.S. cities
15
Facility City State ZIP Site status
Premiere Pharmaceutical Research, LLC Tempe Arizona 85282 —
Clinical Trials Research Lincoln California 95648 —
Long Beach Center for Clinical Research Long Beach California 90806 —
National Research Institute Los Angeles California 90057 —
Sacramento Research Medical Group Sacramento California 95825 —
Orange County Research Center Tustin California 92780 —
Westlake Medical Center Westlake Village California 91361 —
University Clinical Research Deland, LLC DeLand Florida 32720 —
Alan Graff, MD PA Fort Lauderdale Florida 33308 —
Cedar Crosse Research Center Chicago Illinois 60607 —
Orland Primary Care Specialists Orland Park Illinois 60467 —
MD Medical Research Oxon Hill Maryland 20745 —
Lindner Clinical Trial Center Cincinnati Ohio 45219 —
Punzi Medical Center Carrolton Texas 75006 —
Gemini Scientific Madison Wisconsin 53719 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00522925, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 16, 2011 · Synced Oct 27, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00522925 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →