Compare Bosutinib To Imatinib In Subjects With Newly Diagnosed Chronic Phase Philadelphia Chromosome Positive CML
Public ClinicalTrials.gov record NCT00574873. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A PHASE 3 RANDOMIZED, OPEN-LABEL STUDY OF BOSUTINIB VERSUS IMATINIB IN SUBJECTS WITH NEWLY DIAGNOSED CHRONIC PHASE PHILADELPHIA CHROMOSOME POSITIVE CHRONIC MYELOGENOUS LEUKEMIA
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Two-arm, randomized, open-label trial designed to evaluate the efficacy and safety of bosutinib alone compared to imatinib alone in subjects newly diagnosed with chronic phase Chronic Myelogenous Leukemia (CML). The primary endpoint is cytogenetic response rate at one year.
Study identification
- NCT ID
- NCT00574873
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 502 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 5, 2008 (Actual)
- Primary completion
- Aug 31, 2010 (Actual)
- Completion
- May 27, 2015 (Actual)
- Last update posted
- Jan 8, 2019
2008 – 2015
United States locations
- U.S. sites
- 32
- U.S. states
- 13
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Pacific Cancer Medical Center Inc | Anaheim | California | 92801 | — |
| Tower Cancer Research Foundation (TCRF) | Beverly Hills | California | 90211-1848 | — |
| Robert A Moss, MD, FACP, Inc | Fountain Valley | California | 92708 | — |
| UCSD Medical Center-Thornton | La Jolla | California | 92037 | — |
| UCSD Moores Cancer Center | La Jolla | California | 92093 | — |
| UCSD Medical Center-Hillcrest | San Diego | California | 92103 | — |
| Stanford Hospital and Clinics Investigational Drug Services | Stanford | California | 94305 | — |
| Stanford Hospitals and Clinics | Stanford | California | 94305 | — |
| Stanford University Medical Center | Stanford | California | 94305 | — |
| Cancer Care Centers of Florida | Hudson | Florida | 34667 | — |
| Cancer Care Centers of Florida | New Port Richey | Florida | 34652 | — |
| Pasco Pinellas Cancer Center | New Port Richey | Florida | 34652 | — |
| Orlando Health, Inc. | Orlando | Florida | 32806 | — |
| Pasco Pinellas Cancer Center | Tarpon Springs | Florida | 34689 | — |
| Northside Hospital, Inc. - GCS/Annex | Atlanta | Georgia | 30341 | — |
| Indiana Blood and Marrow Transplantation Research Franciscan St. Francis Health Center Inc. | Indianapolis | Indiana | 46237 | — |
| Indiana Blood and Marrow Transplantation Research | Indianapolis | Indiana | 46237 | — |
| Siouxland Hematology-Oncology Associates, LLP | Sioux City | Iowa | 51101 | — |
| Cancer Center of Kansas | Salinas | Kansas | 67401 | — |
| Cancer Center of Kansas | Wichita | Kansas | 67214 | — |
| Kentucky Cancer Clinic | Hazard | Kentucky | 41701-9466 | — |
| Center for Cancer and Blood Disorders | Bethesda | Maryland | 20817 | — |
| Josephine Ford Cancer - Downriver | Brownstown | Michigan | 48183 | — |
| Henry Ford Medical Center- Fairlane | Dearborn | Michigan | 48126 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202-2689 | — |
| Henry Ford Hospital - West Bloomfield | Detroit | Michigan | 48322 | — |
| Regional Cancer Care Associates | Cherry Hill | New Jersey | 08003 | — |
| Study Supplies: Regional Cancer Care Associates | Cherry Hill | New Jersey | 08003 | — |
| Somerset Hematology Oncology Associates | Somerville | New Jersey | 08876 | — |
| San Juan Oncology Associates | Farmington | New Mexico | 87401 | — |
| Associates In Oncology and Hematology | Chattanooga | Tennessee | 37421 | — |
| The University of Texas M.D. Anderson Cancer Center | Houston | Texas | 77030-4009 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 133 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00574873, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 8, 2019 · Synced Nov 3, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00574873 live on ClinicalTrials.gov.