A Multi-Center Trial To Evaluate The Safety And Efficacy Of Pegaptanib Sodium(Macugen) Injected Into The Eye Every 6 Weeks For Up To 2 Years For Macular Swelling Associated With Diabetes, With An Open-Label Macugen Year Extension.
Public ClinicalTrials.gov record NCT00605280. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2/3 Randomized, Controlled, Double-Masked, Multi-Center, Comparative Trial, In Parallel Groups, To Compare The Safety And Efficacy Of Intravitreous Injections Of 0.3 Mg Pegaptanib Sodium (Macugen®), Given As Often As Every 6 Weeks For 2 Years, To Sham Injections In Subjects With Diabetic Macular Edema (DME) Involving The Center Of The Macula With An Open-Label Macugen Year 3 Extension.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of the study is to test whether Macugen injected into the eye improves vision in more patients than the currently existing standard of care laser therapy. The safety of Macugen compared to standard of care laser will also be evaluated.
Study identification
- NCT ID
- NCT00605280
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 317 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 31, 2005
- Primary completion
- Oct 31, 2009
- Completion
- Jun 30, 2011
- Last update posted
- Nov 15, 2018
2005 – 2011
United States locations
- U.S. sites
- 28
- U.S. states
- 17
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Pfizer Investigational Site | Phoenix | Arizona | 85020 | — |
| Pfizer Investigational Site | Tucson | Arizona | 85704 | — |
| Pfizer Investigational Site | Los Angeles | California | 90095 | — |
| Pfizer Investigational Site | Oakland | California | 94609 | — |
| Pfizer Investigational Site | Santa Ana | California | 92705 | — |
| Pfizer Investigational Site | Denver | Colorado | 80230 | — |
| Pfizer Investigational Site | Hamden | Connecticut | 06518 | — |
| Pfizer Investigational Site | Fort Lauderdale | Florida | 33334-4146 | — |
| Pfizer Investigational Site | Tampa | Florida | 33609 | — |
| Pfizer Investigational Site | Tampa | Florida | 33612 | — |
| Pfizer Investigational Site | Augusta | Georgia | 30909 | — |
| Pfizer Investigational Site | ‘Aiea | Hawaii | 96701 | — |
| Pfizer Investigational Site | Indianapolis | Indiana | 46280 | — |
| Pfizer Investigational Site | Wichita | Kansas | 67214 | — |
| Pfizer Investigational Site | Boston | Massachusetts | 02114 | — |
| Pfizer Investigational Site | Detroit | Michigan | 48201-1423 | — |
| Pfizer Investigational Site | Lynbrook | New York | 11563 | — |
| Pfizer Investigational Site | New York | New York | 10021 | — |
| Pfizer Investigational Site | Charlotte | North Carolina | 28210 | — |
| Pfizer Investigational Site | Pittsburgh | Pennsylvania | 15213 | — |
| Pfizer Investigational Site | West Columbia | South Carolina | 29169 | — |
| Pfizer Investigational Site | Abilene | Texas | 79606 | — |
| Pfizer Investigational Site | Fort Worth | Texas | 76104 | — |
| Pfizer Investigational Site | Houston | Texas | 77002 | — |
| Pfizer Investigational Site | McAllen | Texas | 78503 | — |
| Pfizer Investigational Site | San Antonio | Texas | 78240 | — |
| Pfizer Investigational Site | Temple | Texas | 76508 | — |
| Pfizer Investigational Site | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 45 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00605280, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 15, 2018 · Synced Sep 10, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00605280 live on ClinicalTrials.gov.