Dasatinib in Treating Patients With Solid Tumors or Lymphomas That Are Metastatic or Cannot Be Removed By Surgery
Public ClinicalTrials.gov record NCT00608361. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase I Pharmacokinetic Study of Dasatinib (BMS-354825) (NSC-732517) in Patients With Advanced Malignancies and Varying Levels of Liver Dysfunction
Study identification
- NCT ID
- NCT00608361
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- National Cancer Institute (NCI)
- NIH
- Enrollment
- 80 participants
Conditions and interventions
Conditions
- Adult Acute Lymphoblastic Leukemia in Remission
- Adult B Acute Lymphoblastic Leukemia
- Adult Hepatocellular Carcinoma
- Adult Nasal Type Extranodal NK/T-Cell Lymphoma
- Adult Solid Neoplasm
- Adult T Acute Lymphoblastic Leukemia
- Advanced Adult Hepatocellular Carcinoma
- Anaplastic Large Cell Lymphoma
- Angioimmunoblastic T-Cell Lymphoma
- Chronic Lymphocytic Leukemia
- Cutaneous B-Cell Non-Hodgkin Lymphoma
- Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue
- Hepatosplenic T-Cell Lymphoma
- Intraocular Lymphoma
- Localized Non-Resectable Adult Liver Carcinoma
- Localized Resectable Adult Liver Carcinoma
- Lymphomatous Involvement of Non-Cutaneous Extranodal Site
- Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma
- Nodal Marginal Zone Lymphoma
- Progressive Hairy Cell Leukemia Initial Treatment
- Recurrent Adult Acute Lymphoblastic Leukemia
- Recurrent Adult Burkitt Lymphoma
- Recurrent Adult Diffuse Large Cell Lymphoma
- Recurrent Adult Diffuse Mixed Cell Lymphoma
- Recurrent Adult Diffuse Small Cleaved Cell Lymphoma
- Recurrent Adult Grade III Lymphomatoid Granulomatosis
- Recurrent Adult Hodgkin Lymphoma
- Recurrent Adult Immunoblastic Lymphoma
- Recurrent Adult Liver Carcinoma
- Recurrent Adult Lymphoblastic Lymphoma
- Recurrent Adult T-Cell Leukemia/Lymphoma
- Recurrent Cutaneous T-Cell Non-Hodgkin Lymphoma
- Recurrent Grade 1 Follicular Lymphoma
- Recurrent Grade 2 Follicular Lymphoma
- Recurrent Grade 3 Follicular Lymphoma
- Recurrent Mantle Cell Lymphoma
- Recurrent Marginal Zone Lymphoma
- Recurrent Mycosis Fungoides and Sezary Syndrome
- Recurrent Small Lymphocytic Lymphoma
- Refractory Chronic Lymphocytic Leukemia
- Refractory Hairy Cell Leukemia
- Small Intestinal Lymphoma
- Splenic Marginal Zone Lymphoma
- Stage II Small Lymphocytic Lymphoma
- Stage III Adult Burkitt Lymphoma
- Stage III Adult Diffuse Large Cell Lymphoma
- Stage III Adult Diffuse Mixed Cell Lymphoma
- Stage III Adult Diffuse Small Cleaved Cell Lymphoma
- Stage III Adult Hodgkin Lymphoma
- Stage III Adult Immunoblastic Lymphoma
- Stage III Adult Lymphoblastic Lymphoma
- Stage III Adult T-Cell Leukemia/Lymphoma
- Stage III Chronic Lymphocytic Leukemia
- Stage III Cutaneous T-Cell Non-Hodgkin Lymphoma
- Stage III Grade 1 Follicular Lymphoma
- Stage III Grade 2 Follicular Lymphoma
- Stage III Grade 3 Follicular Lymphoma
- Stage III Mantle Cell Lymphoma
- Stage III Marginal Zone Lymphoma
- Stage III Small Lymphocytic Lymphoma
- Stage IIIA Mycosis Fungoides and Sezary Syndrome
- Stage IIIB Mycosis Fungoides and Sezary Syndrome
- Stage IV Adult Burkitt Lymphoma
- Stage IV Adult Diffuse Large Cell Lymphoma
- Stage IV Adult Diffuse Mixed Cell Lymphoma
- Stage IV Adult Diffuse Small Cleaved Cell Lymphoma
- Stage IV Adult Hodgkin Lymphoma
- Stage IV Adult Immunoblastic Lymphoma
- Stage IV Adult Lymphoblastic Lymphoma
- Stage IV Adult T-Cell Leukemia/Lymphoma
- Stage IV Chronic Lymphocytic Leukemia
- Stage IV Cutaneous T-Cell Non-Hodgkin Lymphoma
- Stage IV Grade 1 Follicular Lymphoma
- Stage IV Grade 2 Follicular Lymphoma
- Stage IV Grade 3 Follicular Lymphoma
- Stage IV Mantle Cell Lymphoma
- Stage IV Marginal Zone Lymphoma
- Stage IV Small Lymphocytic Lymphoma
- Stage IVA Mycosis Fungoides and Sezary Syndrome
- Stage IVB Mycosis Fungoides and Sezary Syndrome
- T-Cell Large Granular Lymphocyte Leukemia
- Testicular Lymphoma
- Untreated Adult Acute Lymphoblastic Leukemia
- Untreated Hairy Cell Leukemia
- Waldenstrom Macroglobulinemia
Interventions
- Dasatinib Drug
- Pharmacological Study Other
Drug · Other
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 30, 2008
- Primary completion
- Jul 31, 2014
- Completion
- Jul 31, 2014
- Last update posted
- Jul 1, 2015
2008 – 2014
United States locations
- U.S. sites
- 23
- U.S. states
- 6
- U.S. cities
- 17
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| City of Hope Comprehensive Cancer Center | Duarte | California | 91010 | — |
| Los Angeles County-USC Medical Center | Los Angeles | California | 90033 | — |
| USC / Norris Comprehensive Cancer Center | Los Angeles | California | 90033 | — |
| University of California Davis Comprehensive Cancer Center | Sacramento | California | 95817 | — |
| Hays Medical Center | Hays | Kansas | 67601 | — |
| Hutchinson Regional Medical Center | Hutchinson | Kansas | 67502 | — |
| University of Kansas Cancer Center | Kansas City | Kansas | 66160 | — |
| Olathe Cancer Center | Olathe | Kansas | 66061 | — |
| Via Christi Hospital-Pittsburg | Pittsburg | Kansas | 66762 | — |
| Salina Regional Health Center | Salina | Kansas | 67401 | — |
| Saint Francis Hospital and Medical Center - Topeka | Topeka | Kansas | 66606 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Truman Medical Center | Kansas City | Missouri | 64108 | — |
| Audie L Murphy Veterans Affairs Hospital | San Antonio | Texas | 78209 | — |
| Cancer Therapy and Research Center at The UT Health Science Center at San Antonio | San Antonio | Texas | 78229 | — |
| University Hospital | San Antonio | Texas | 78229 | — |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78229 | — |
| Scott and White Memorial Hospital | Temple | Texas | 76508 | — |
| Swedish Medical Center-Edmonds | Edmonds | Washington | 98026 | — |
| Swedish Cancer Institute-Issaquah | Issaquah | Washington | 98029 | — |
| Swedish Medical Center-Ballard Campus | Seattle | Washington | 98107 | — |
| Swedish Medical Center-First Hill | Seattle | Washington | 98122-4307 | — |
| University of Washington Medical Center | Seattle | Washington | 98195 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00608361, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 1, 2015 · Synced May 20, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00608361 live on ClinicalTrials.gov.