ClinicalTrials.gov record
Terminated Phase 1 Interventional

A Study of R1507 in Combination With Multiple Standard Chemotherapy Treatments in Patients With Advanced Solid Tumors

ClinicalTrials.gov ID: NCT00811993

Public ClinicalTrials.gov record NCT00811993. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 4, 2026, 9:52 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase Ib Study To Evaluate The Safety Of Combining IGF-1R Antagonist R1507 With Multiple Standard Chemotherapy Drug Treatments In Patients With Advanced Malignancies

Study identification

NCT ID
NCT00811993
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 1
Lead sponsor
Hoffmann-La Roche
Industry
Enrollment
104 participants

Conditions and interventions

Conditions

Interventions

  • RG1507 Drug
  • RO1507 Drug
  • bevacizumab [Avastin] Drug
  • capecitabine [Xeloda] Drug
  • carboplatin Drug
  • cetuximab Drug
  • docetaxel Drug
  • erlotinib [Tarceva] Drug
  • etoposide Drug
  • gemcitabine Drug
  • irinotecan Drug
  • mFOLFOX6 Drug
  • paclitaxel Drug
  • pemetrexel Drug
  • sorafenib Drug
  • temozolomide Drug
  • trastuzumab [Herceptin] Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 31, 2009
Primary completion
Nov 30, 2012
Completion
Nov 30, 2012
Last update posted
Nov 1, 2016

2009 – 2012

United States locations

U.S. sites
8
U.S. states
7
U.S. cities
8
Facility City State ZIP Site status
Not listed Tucson Arizona 85724
Not listed San Francisco California 94115
Not listed Santa Monica California 90025
Not listed Washington D.C. District of Columbia 20007
Not listed Chicago Illinois 60637
Not listed Rochester Minnesota 55905
Not listed Chapel Hill North Carolina 27514
Not listed Houston Texas 77030

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00811993, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 1, 2016 · Synced May 4, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00811993 live on ClinicalTrials.gov.

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