Efficacy and Safety of Azilsartan Medoxomil Plus Chlorthalidone in Participants With Moderate to Severe Hypertension
Public ClinicalTrials.gov record NCT00846365. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Double-Blind, Randomized, Efficacy and Safety Study Comparing the TAK-491 Plus Chlorthalidone Fixed-Dose Combination vs Benicar HCT® (Olmesartan Medoxomil-Hydrochlorothiazide) in Subjects With Moderate to Severe Essential Hypertension
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine the efficacy and safety of azilsartan medoxomil combined with chlorthalidone, once daily (QD), in participants with moderate to severe essential hypertension.
Study identification
- NCT ID
- NCT00846365
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,085 participants
Conditions and interventions
Conditions
Interventions
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 2009 (Type not available)
- Primary completion
- Jun 2010 (Actual)
- Completion
- Jun 2010 (Actual)
- Last update posted
- Mar 13, 2012
2009 – 2010
United States locations
- U.S. sites
- 70
- U.S. states
- 28
- U.S. cities
- 70
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Birmingham | Alabama | — | — |
| Not listed | Haleyville | Alabama | — | — |
| Not listed | Hueytown | Alabama | — | — |
| Not listed | Jasper | Alabama | — | — |
| Not listed | Tallassee | Alabama | — | — |
| Not listed | Green Valley | Arizona | — | — |
| Not listed | Phoenix | Arizona | — | — |
| Not listed | Long Beach | California | — | — |
| Not listed | National City | California | — | — |
| Not listed | Roseville | California | — | — |
| Not listed | San Francisco | California | — | — |
| Not listed | San Jose | California | — | — |
| Not listed | Newark | Delaware | — | — |
| Not listed | Clearwater | Florida | — | — |
| Not listed | Jacksonville | Florida | — | — |
| Not listed | Jupiter | Florida | — | — |
| Not listed | Miami | Florida | — | — |
| Not listed | Ocala | Florida | — | — |
| Not listed | Pembroke Pines | Florida | — | — |
| Not listed | Plant City | Florida | — | — |
| Not listed | Tallahassee | Florida | — | — |
| Not listed | Arlington Heights | Illinois | — | — |
| Not listed | Chicago | Illinois | — | — |
| Not listed | Gurnee | Illinois | — | — |
| Not listed | Avon | Indiana | — | — |
| Not listed | Wichita | Kansas | — | — |
| Not listed | Louisville | Kentucky | — | — |
| Not listed | Auburn | Maine | — | — |
| Not listed | Baltimore | Maryland | — | — |
| Not listed | Brockton | Massachusetts | — | — |
| Not listed | Haverhill | Massachusetts | — | — |
| Not listed | North Dartmouth | Massachusetts | — | — |
| Not listed | Bingham Farms | Michigan | — | — |
| Not listed | Stevensville | Michigan | — | — |
| Not listed | Olive Branch | Mississippi | — | — |
| Not listed | Kansas City | Missouri | — | — |
| Not listed | New York | New York | — | — |
| Not listed | Burlington | North Carolina | — | — |
| Not listed | Charlotte | North Carolina | — | — |
| Not listed | Hickory | North Carolina | — | — |
| Not listed | Shelby | North Carolina | — | — |
| Not listed | Akron | Ohio | — | — |
| Not listed | Cleveland | Ohio | — | — |
| Not listed | Columbus | Ohio | — | — |
| Not listed | Marion | Ohio | — | — |
| Not listed | Middleburg Heights | Ohio | — | — |
| Not listed | Willoughby Hills | Ohio | — | — |
| Not listed | Norman | Oklahoma | — | — |
| Not listed | Bensalem | Pennsylvania | — | — |
| Not listed | Erie | Pennsylvania | — | — |
| Not listed | Reading | Pennsylvania | — | — |
| Not listed | Cranston | Rhode Island | — | — |
| Not listed | Cumberland | Rhode Island | — | — |
| Not listed | North Charleston | South Carolina | — | — |
| Not listed | Jackson | Tennessee | — | — |
| Not listed | Kingsport | Tennessee | — | — |
| Not listed | Milan | Tennessee | — | — |
| Not listed | Austin | Texas | — | — |
| Not listed | Corpus Christi | Texas | — | — |
| Not listed | Dallas | Texas | — | — |
| Not listed | Houston | Texas | — | — |
| Not listed | San Antonio | Texas | — | — |
| Not listed | Salt Lake City | Utah | — | — |
| Not listed | Arlington | Virginia | — | — |
| Not listed | Burke | Virginia | — | — |
| Not listed | Charlottesville | Virginia | — | — |
| Not listed | Manassas | Virginia | — | — |
| Not listed | Lakewood | Washington | — | — |
| Not listed | Port Orchard | Washington | — | — |
| Not listed | Menomonee Falls | Wisconsin | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 10 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00846365, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 13, 2012 · Synced Oct 25, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00846365 live on ClinicalTrials.gov.