ClinicalTrials.gov record
An Investigational Drug, PF-02341066 Is Being Studied Versus Standard Of Care In Patients With Advanced Non-Small Cell Lung Cancer With A Specific Gene Profile Involving The Anaplastic Lymphoma Kinase (ALK) Gene
ClinicalTrials.gov ID: NCT00932893
Public ClinicalTrials.gov record NCT00932893. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase 3, Randomized, Open-label Study Of The Efficacy And Safety Of Pf-02341066 Versus Standard Of Care Chemotherapy (Pemetrexed Or Docetaxel) In Patients With Advanced Non-small Cell Lung Cancer (Nsclc) Harboring A Translocation Or Inversion Event Involving The Anaplastic Lymphoma Kinase (Alk) Gene Locus
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a Phase 3 trial comparing the safety and anti-tumor activity of PF-02341066 versus pemetrexed or docetaxel in patients with advanced non-small cell lung cancer with specific gene profile involving the ALK gene after failure of one previous chemotherapy regimen that included one platinum drug.
Study identification
- NCT ID
- NCT00932893
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 347 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 2009 (Type not available)
- Primary completion
- Mar 2012 (Actual)
- Completion
- Jan 2016 (Actual)
- Last update posted
- Jan 2, 2017
2009 – 2016
United States locations
- U.S. sites
- 119
- U.S. states
- 23
- U.S. cities
- 61
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Arkansas for Medical Research, Winthrop Rockefeller Cancer Institute | Little Rock | Arkansas | 72205 | — |
| Comprehensive Blood and Cancer Center | Bakersfield | California | 93309 | — |
| Tower Cancer Research Foundation | Beverly Hills | California | 90211-1850 | — |
| Tower Hematology Oncology Medical Group | Beverly Hills | California | 90211 | — |
| UCSD Medical Center -La Jolla | La Jolla | California | 92037 | — |
| Moores UC San Diego Cancer Center | La Jolla | California | 92093-0698 | — |
| Drug Shipping Address: [IRB# 10-001530] Ronald Reagan UCLA | Los Angeles | California | 90095-6984 | — |
| Ronald Reagan UCLA Medical Center | Los Angeles | California | 90095 | — |
| UCLA Hematology Oncology | Los Angeles | California | 90095 | — |
| UCLA Ophthalmic Oncology Center | Los Angeles | California | 90095 | — |
| University of California-Los Angeles | Los Angeles | California | 90095 | — |
| Ship Drug To : Kevin Kong- University of California, Irvine-Pharmacy | Orange | California | 92868-3298 | — |
| University of California, Irvine-Medical Center | Orange | California | 92868-3298 | — |
| Stanford University-Cancer Center | Palo Alto | California | 94305 | — |
| UC Davis Cancer Center | Sacramento | California | 95817 | — |
| University of California Davis Medical Center | Sacramento | California | 95817 | — |
| UCSD Medical Center- Hillcrest | San Diego | California | 92103 | — |
| Santa Monica-UCLA Medical Center and Orthopaedic Hospital | Santa Monica | California | 90404 | — |
| University of California, Los Angeles | Santa Monica | California | 90404 | — |
| Redwood Regional Medical Group, Inc. | Santa Rosa | California | 95403 | — |
| Drug Shipment: University of Colorado Cancer Center, Anschutz Cancer Pavilion | Aurora | Colorado | 80045 | — |
| University of Colorado Denver (CTRC) | Aurora | Colorado | 80045 | — |
| Unviersity of Colorado Hospital, Anschutz Cancer Pavilion | Aurora | Colorado | 80045 | — |
| Unviersity of Colorado Hospital, Anschutz Inpatient Pavilion | Aurora | Colorado | 80045 | — |
| Kaiser Permanente | Denver | Colorado | 80205 | — |
| Kaiser Permanente | Lafayette | Colorado | 80026 | — |
| Drug Shipping for Yale; C/O Thomas Ferencz, RPh, BCOP | New Haven | Connecticut | 06510 | — |
| Smilow Cancer Hospital at Yale New Haven | New Haven | Connecticut | 06510 | — |
| Clinical Trial Office | New Haven | Connecticut | 06519 | — |
| Yale Cancer Center | New Haven | Connecticut | 06520 | — |
| Memorial Cancer Institute | Hollywood | Florida | 33021 | — |
| Cancer Center of South Florida Foundation, Inc. | Lake Worth | Florida | 33461 | — |
| Memorial Cancer Institute (West) | Pembroke Pines | Florida | 33028 | — |
| H Lee Moffitt Cancer Center & Research Institute | Tampa | Florida | 33612 | — |
| Emory University Hospital Midtown | Atlanta | Georgia | 30308 | — |
| Emory Clinic | Atlanta | Georgia | 30322 | — |
| Emory University Clinic | Atlanta | Georgia | 30322 | — |
| Emory University Hospital | Atlanta | Georgia | 30322 | — |
| Winship Cancer Institution | Atlanta | Georgia | 30322 | — |
| Georgia Cancer Specialists-Administrative Annex | Atlanta | Georgia | 30341 | — |
| Georgia Cancer Specialists - Stemmer | Decatur | Georgia | 30033 | — |
| Georgia Cancer Specialists-Macon | Macon | Georgia | 31217 | — |
| Georgia Cancer Specialists-Kennestone | Marietta | Georgia | 30060 | — |
| Georgia Cancer Specialists | Sandy Springs | Georgia | 30342 | — |
| Cancer Research Center of Hawaii | Honolulu | Hawaii | 96813 | — |
| Hawaii Medical Center East | Honolulu | Hawaii | 96813 | — |
| OnCare Hawaii, Inc. | Honolulu | Hawaii | 96813 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| University of Chicago Medical Center | Chicago | Illinois | 60637 | — |
| Ingalls Memorial Hospital (Drug Shipment Only) | Harvey | Illinois | 60426 | — |
| Ingalls Memorial Hospital | Harvey | Illinois | 60426 | — |
| Monroe Medical Associates | Harvey | Illinois | 60426 | — |
| Monroe Medical Associates | Tinley Park | Illinois | 60477 | — |
| Indiana University Hospital | Indianapolis | Indiana | 46202 | — |
| Indiana University Melvin and Bren Simon Cancer Center | Indianapolis | Indiana | 46202 | — |
| Ship Drug to: Investigational Drug Services | Indianapolis | Indiana | 46202 | — |
| Wishard Memorial Hospital | Indianapolis | Indiana | 46202 | — |
| Springmill Medical Clinic | Indianapolis | Indiana | 46290 | — |
| Monroe Medical Associates | Munster | Indiana | 46321 | — |
| The Community Hospital | Munster | Indiana | 46321 | — |
| Johns Hopkins Sidney Kimmel Comprehensive Cancer Center | Baltimore | Maryland | 21231 | — |
| Massachusette General Hospital | Boston | Massachusetts | 02114 | — |
| Massachussetts General Hospital | Boston | Massachusetts | 02114 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Beth Isreal Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02215 | — |
| DFCI/Pharmacy (Drug Shipment Only) | Boston | Massachusetts | 02215 | — |
| Karmanos Cancer Institute | Detroit | Michigan | 48201 | — |
| Lawrence and Idell Weisberg Cancer Treatment Center | Farmington Hills | Michigan | 48334 | — |
| Siteman Cancer Center | City of Saint Peters | Missouri | 63376 | — |
| Siteman Cancer Center- West County | Creve Coeur | Missouri | 63141 | — |
| Barnes-Jewish Hospital | St Louis | Missouri | 63110-1094 | — |
| Washington University, School of Medicine | St Louis | Missouri | 63110 | — |
| Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire | 03756-0001 | — |
| NSLIJ Health System/Monter Cancer Center | Lake Success | New York | 11042 | — |
| Memorial Sloan-Kettering Cancer Center: Rockefeller Outpatient Pavilion | New York | New York | 10022 | — |
| Columbia University Medical Center | New York | New York | 10032 | — |
| Memorial Sloan-Kettering Cancer Center | New York | New York | 10065 | — |
| Department of Medicine MSG at SUNY HSC at Syracuse, INC., d/b/a University Physicians | Oneida | New York | 13421 | — |
| Department of Medicine MSG at SUNY HSC at Syracuse, INC., d/b/a University Physicians | Oswego | New York | 13126 | — |
| SUNY Upstate Medical University | Syracuse | New York | 13210-2306 | — |
| Department of Medicine MSG at SUNY HSC at Syracuse, INC., d/b/a University Physicians | Syracuse | New York | 13210 | — |
| Investigational Drug Service, Pharmacy Department, UNC Hospitals | Chapel Hill | North Carolina | 27514 | — |
| UNC Health Care, NC Cancer Hospital Infusion/lnpatient Pharmacy (CHIP) | Chapel Hill | North Carolina | 27514 | — |
| UNC Hospitals | Chapel Hill | North Carolina | 27599-7600 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| The Ohio State University Hospital East | Columbus | Ohio | 43205 | — |
| The Ohio State University James Cancer Hospital and Solove Research Institute | Columbus | Ohio | 43210 | — |
| James Care in Kenny | Columbus | Ohio | 43221 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| Penn State Milton S. Hershey Medical Center, Penn State Hershey Cancer Institute | Hershey | Pennsylvania | 17033-0850 | — |
| Abramson Cancer Center of the University of Pennsylvania at Perelman Center for Advanced Medicine | Philadelphia | Pennsylvania | 19104 | — |
| Penn Presbyterian Medical Center | Philadelphia | Pennsylvania | 19104 | — |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | — |
| University of Pittsburgh Medical Center-Shadyside | Pittsburgh | Pennsylvania | 15232 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15232 | — |
| Vincent Armenio, MD | East Providence | Rhode Island | 02914 | — |
| Pharma Resource | East Providence | Rhode Island | 02915 | — |
| Tennessee Oncology, PLLC | Dickson | Tennessee | 37055 | — |
| Tennessee Oncology, PLLC | Franklin | Tennessee | 37067 | — |
| Tennessee Oncology, PLLC | Gallatin | Tennessee | 37066 | — |
| Tennessee Oncology, PLLC | Hermitage | Tennessee | 37076 | — |
| Tennessee Oncology, PLLC | Lebanon | Tennessee | 37087 | — |
| Tennessee Oncology, PLLC | Murfreesboro | Tennessee | 37130 | — |
| Sarah Cannon Research Institute | Nashville | Tennessee | 37203 (Pharmacy) | — |
| Sarah Cannon Research Institute | Nashville | Tennessee | 37203 | — |
| Tennessee Oncology, PLLC | Nashville | Tennessee | 37203 | — |
| Tennessee Oncology, PLLC | Nashville | Tennessee | 37205 | — |
| Tennessee Oncology, PLLC | Nashville | Tennessee | 37207 | — |
| Tennessee Oncology, PLLC | Nashville | Tennessee | 37211 | — |
| The Vanderbilt Cancer Clinic | Nashville | Tennessee | 37232-5536 | — |
| The Vanderbilt Chemo Pharmacy | Nashville | Tennessee | 37232-7610 | — |
| Tennessee Oncology, PLLC | Smyrna | Tennessee | 37167 | — |
| The University of Texas | Houston | Texas | 77030 | — |
| Swedish Cancer Institute | Seattle | Washington | 98104 | — |
| Seattle Cancer Care Alliance | Seattle | Washington | 98109 | — |
| Investigational Drug Service | Seattle | Washington | 98122 | — |
| Swedish Medical Center | Seattle | Washington | 98122 | — |
| University of Washington Medical Center | Seattle | Washington | 98195 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 145 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00932893, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 2, 2017 · Synced Oct 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00932893 live on ClinicalTrials.gov.