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Completed Phase 2 Interventional

Oral Triple Combination Antiviral Drug Therapy for Treatment of Influenza A in Immunocompromised Subjects

ClinicalTrials.gov ID: NCT00979251

Public ClinicalTrials.gov record NCT00979251. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 30, 2026, 5:54 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized Open Label Study Comparing the Efficacy, Safety, and Tolerability of Oral Administration of Amantadine and Ribavirin With Oseltamivir Versus Oseltamivir to Influenza A Virus Infected Immunocompromised Subjects

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This Phase 2, open label, randomized study will investigate the virologic benefit, clinical efficacy, safety, and tolerability of amantadine and ribavirin with oseltamivir (TCAD) versus oseltamivir monotherapy for the treatment of all strains of influenza A in immunocompromised adult and pediatric subjects.

Study identification

NCT ID
NCT00979251
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Adamas Pharmaceuticals, Inc.
Industry
Enrollment
2 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
1 Year to 65 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 2009 (Type not available)
Primary completion
May 2010 (Actual)
Completion
Aug 2011 (Actual)
Last update posted
Apr 14, 2014

2009 – 2011

United States locations

U.S. sites
16
U.S. states
11
U.S. cities
14
Facility City State ZIP Site status
Adamas Investigational Site San Francisco California 94114 —
Adamas Investigational Site San Francisco California 94115 —
Adamas Investigational Site San Francisco California — —
Adamas Investigational Site Hollywood Florida — —
Adamas Investigational Site Miramar Florida — —
Adamas Investigational Site Pinellas Park Florida — —
Adamas Investigational Site Honolulu Hawaii — —
Adamas Investigational Site Owensboro Kentucky — —
Adamas Investigational Site New Orleans Louisiana — —
Adamas Investigational Site Las Vegas Nevada — —
Adamas Investigational Site New York New York — —
Adamas Investigational Site Rapid City South Dakota 57702 —
Adamas Investigational Site Memphis Tennessee 38105 —
Adamas Investigational Site Amarillo Texas — —
Adamas Investigational Site Seattle Washington — —
Adamas Investigational Site Tacoma Washington — —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 9 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00979251, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 14, 2014 · Synced Oct 30, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00979251 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →