ClinicalTrials.gov record
Completed Phase 2 Interventional Results available

External Beam Radiation Therapy and Cetuximab Followed by Irinotecan and Cetuximab for Children and Young Adults With Newly Diagnosed Diffuse Pontine Tumors and High-Grade Astrocytomas

ClinicalTrials.gov ID: NCT01012609

Public ClinicalTrials.gov record NCT01012609. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 11, 2026, 11:37 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase II Trial of External Beam Radiation Therapy and Cetuximab Followed by Irinotecan and Cetuximab for Children and Young Adults With Newly Diagnosed Diffuse Pontine Tumors and High-Grade Astrocytomas (POE08-01)

Study identification

NCT ID
NCT01012609
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Enrollment
47 participants

Conditions and interventions

Conditions

Interventions

  • cetuximab in conjunction with external beam radiation therapy, followed by cetuximab and irinotecan Other

Other

Eligibility (public fields only)

Age range
3 Years to 21 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 29, 2009
Primary completion
Jan 14, 2018
Completion
Jan 14, 2018
Last update posted
Mar 13, 2022

2009 – 2018

United States locations

U.S. sites
11
U.S. states
10
U.S. cities
11
Facility City State ZIP Site status
Phoenix Children'S Hospital Phoenix Arizona 85016
University of Colorado Health Sciences Center Denver Colorado
University of Florida Gainesville Florida
MD Anderson Cancer Center Orlando at Arnold Palmer Hospital for Children Orlando Florida 32806
Children's Healthcare of Atlanta at Egleston Atlanta Georgia 30322
John Hopkins Medical Center Baltimore Maryland 21287
Dana Farber Cancer Institute Boston Massachusetts 02115
Children's Mercy Hospital & Clinics Kansas City Missouri 64108
Memorial Sloan-Kettering Cancer Center New York New York 10065
Md Anderson Cancer Center Houston Texas 77030
Seattle Children'S Hospital Seattle Washington

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01012609, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 13, 2022 · Synced May 11, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01012609 live on ClinicalTrials.gov.

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