Safety Study of a Single IVT Injection of QPI-1007 in Chronic Optic Nerve Atrophy and Recent Onset NAION Patients
Public ClinicalTrials.gov record NCT01064505. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase I Open-Label, Dose Escalation Trial of QPI-1007 Delivered by a Single Intravitreal Injection to Patients With Optic Nerve Atrophy (Stratum I) and Acute Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION) (Stratum II)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is an open-label, dose escalation, safety, tolerability and pharmacokinetic study, where active study drug (QPI-1007) will be given to all patients who participate. This study will determine whether QPI-1007 is safe when it is injected into the eye. The study will also reveal if there are any side effects of the drug and how long it takes for the body to clear the drug.
Study identification
- NCT ID
- NCT01064505
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1
- Enrollment
- 48 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 31, 2010
- Primary completion
- Mar 31, 2013
- Completion
- Mar 31, 2013
- Last update posted
- May 12, 2013
2010 – 2013
United States locations
- U.S. sites
- 22
- U.S. states
- 16
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Retinal Consultants of Arizona | Phoenix | Arizona | 85014 | — |
| Retina-Vitreous Associates Medical Group | Beverly Hills | California | 90211 | — |
| Jules Stein Eye Institute, University of California, Los Angeles | Los Angeles | California | 90049 | — |
| Rocky Mountain Multiple Sclerosis Center at Anschutz Medical Campus, University of Colorado | Aurora | Colorado | 80045 | — |
| Bascom Palmer at the University of Miami | Miami | Florida | 33136 | — |
| Sarasota Retina Institute | Sarasota | Florida | 34239 | — |
| University of Illinois at Chicago, Eye and Ear Infirmary | Chicago | Illinois | 60612 | — |
| Kansas University Medical Center | Kansas City | Kansas | 66208 | — |
| University of Kentucky, Department of Ophthalmology | Lexington | Kentucky | 40536 | — |
| University of Minnesota, Department of Ophthalmology | Minneapolis | Minnesota | 55455 | — |
| Mason Eye Institute, University of Missouri | Columbia | Missouri | 65212 | — |
| New York Eye and Ear Infirmary | New York | New York | 10003 | — |
| Flaum Eye Institute, University of Rochester Medical Center | Rochester | New York | 14642 | — |
| Western Carolina Retinal Associates | Asheville | North Carolina | 28803 | — |
| Charlotte Eye, Ear, Nose and Throat Associates, PA | Charlotte | North Carolina | 28210 | — |
| Duke Eye Center, Duke University Medical Center | Durham | North Carolina | 27705 | — |
| Cole Eye Institute, Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| University of Pennsylvania, Department of Ophthalmology | Philadelphia | Pennsylvania | 19104 | — |
| Allegheny Ophthalmic and Orbital Associates | Pittsburgh | Pennsylvania | 15212 | — |
| Alkek Eye Center Baylor College of Medicine | Houston | Texas | 77030 | — |
| John A. Moran Eye Center at the University of Utah | Salt Lake City | Utah | 84132 | — |
| Virginia Commonwealth University | Richmond | Virginia | 23298 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 6 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01064505, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 12, 2013 · Synced Sep 7, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01064505 live on ClinicalTrials.gov.