Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

ClinicalTrials.gov ID: NCT01093586

Public ClinicalTrials.gov record NCT01093586. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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Official title

Umbilical Cord Blood (UCB) Allogeneic Stem Cell Transplant for Hematologic Malignancies

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

RATIONALE: Giving chemotherapy before a donor umbilical cord blood transplant (UCBT) helps stop the growth of cancer and abnormal cells and helps stop the patient's immune system from rejecting the donor's stem cells. When the stem cells from an unrelated donor, that do not exactly match the patient's blood, are infused into the patient they may help the patient's bone marrow make stem cells, red blood cells, white blood cells, and platelets. Sometimes the transplanted cells from a donor can make an immune response against the body's normal cells. Giving antithymocyte globulin before transplant and cyclosporine and mycophenolate mofetil after transplant may stop this from happening. PURPOSE: This phase II trial is studying how well donor umbilical cord blood stem cell transplant works in treating patients with hematologic malignancies.

Study identification

NCT ID: NCT01093586
Recruitment status: Completed
Study type: Interventional
Phase: Phase 2
Lead sponsor: Case Comprehensive Cancer Center; Other
Enrollment: 14 participants

Conditions and interventions

Conditions

Interventions

double-unit umbilical cord blood transplantation Procedure
cytogenetic analysis Other
bone marrow aspiration Procedure
fluorescence in situ hybridization Other
busulfan Drug
cyclophosphamide Drug
anti-thymocyte globulin Drug
methylprednisolone Drug
cyclosporine Drug
mycophenolate mofetil Drug
flow cytometry Other
allogeneic hematopoietic stem cell transplantation Procedure

Procedure · Other · Drug

Eligibility (public fields only)

Age range: 12 Years to 64 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Aug 31, 2007
Primary completion: Nov 30, 2015
Completion: Nov 30, 2015
Last update posted: Jan 22, 2019

2007 – 2015

United States locations

U.S. sites: 1
U.S. states: 1
U.S. cities: 1

Facility	City	State	ZIP	Site status
Case Medical Center, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center	Cleveland	Ohio	44106	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT01093586, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Jan 22, 2019 · Synced Sep 4, 2026

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The complete protocol, eligibility criteria, and contact information for NCT01093586 live on ClinicalTrials.gov.

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