A Study to Determine if There is a Possible Association Between NAION and Phosphodiesterase Type 5 (PDE5) Inhibitors
Public ClinicalTrials.gov record NCT01131104. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Prospective Case-crossover Study to Evaluate the Possible Association Between the Use of PDE5 Inhibitors and the Risk of Acute Nonarteritic Anterior Ischemic Optic Neuropathy (NAION)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Study H6D-MC-LVHQ is an observational, non-interventional, multi-center, prospective, case-crossover study to evaluate the possible association between the use of phosphodiesterase type 5 (PDE5) inhibitors and the risk of acute nonarteritic anterior ischemic optic neuropathy (NAION) in males. Subjects with newly diagnosed NAION will be asked via a structured questionnaire about their use of PDE5 inhibitors and other risk factors prior to the onset of their vision loss.
Study identification
- NCT ID
- NCT01131104
- Recruitment status
- Completed
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 345 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Male
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 2010 (Type not available)
- Primary completion
- Dec 2015 (Actual)
- Completion
- Dec 2015 (Actual)
- Last update posted
- Apr 5, 2018
2010 – 2015
United States locations
- U.S. sites
- 44
- U.S. states
- 22
- U.S. cities
- 43
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama Birmingham | Birmingham | Alabama | 35295 | — |
| Cockerham Eye Consultant | Los Altos | California | 94024 | — |
| Precision Eye Care | National City | California | 91950 | — |
| North Bay Eye Associates, Inc. | Petaluma | California | 94954 | — |
| Russell P Edwards M.D. | San Diego | California | 92103 | — |
| Pacific Eye Associates | San Francisco | California | 94115 | — |
| Eye Surgical & Medical Associates, Inc. | Visalia | California | 93277 | — |
| The Eye Care Group | New Haven | Connecticut | 06708 | — |
| Avail Clinical Research LLC | DeLand | Florida | 32720 | — |
| University of Florida - Gainesville | Gainesville | Florida | 32611 | — |
| Florida Retina Consultants | Lakeland | Florida | 33805 | — |
| University of Miami School of Medicine | Miami | Florida | 33136 | — |
| Sarasota Retina Institute | Sarasota | Florida | 34239 | — |
| USF Eye Institute | Tampa | Florida | 33612 | — |
| University of Illinois At Chicago Med Center | Chicago | Illinois | 60612 | — |
| Northwestern University | Evanston | Illinois | 60208 | — |
| Northshore Eye and Vision Center | Glenview | Illinois | 60026 | — |
| Midwest Eye Institute | Indianapolis | Indiana | 46290 | — |
| Univ KY Clinical Resch Org- KY Clinic | Lexington | Kentucky | 40536 | — |
| Paducah Retinal Center | Paducah | Kentucky | 42001 | — |
| Bethesda Neurology, LLC | Bethesda | Maryland | 20814 | — |
| Longwood Medical Eye Center | Boston | Massachusetts | 02215 | — |
| Atlantic Clinical Trials, LLC | Watertown | Massachusetts | 02472 | — |
| Henry Ford Health System | Dearborn | Michigan | 48126 | — |
| Neuro-Ophthalmic Services | Royal Oak | Michigan | 48073 | — |
| University of Minnesota Medical School | Minneapolis | Minnesota | 55455 | — |
| Saint Louis University | St Louis | Missouri | 63104 | — |
| JFK Medical Center, NJ Neuroscience Institute | Edison | New Jersey | 08820 | — |
| Stony Brook University Medical Center | East Setauket | New York | 11733 | — |
| E.S. Harkness Eye Institute | New York | New York | 10032 | — |
| Montefiore Medical Center | The Bronx | New York | 10467 | — |
| PMG Research of Salisbury | Salisbury | North Carolina | 28144 | — |
| Ohio State Univ College Of Medicine | Columbus | Ohio | 46210 | — |
| Dr. Daniel Lin | Oregon | Ohio | 43616 | — |
| Family Eye Care | Lancaster | Pennsylvania | 17601 | — |
| University of Pennsylvania Hospital | Philadelphia | Pennsylvania | 19104 | — |
| Allegheny Ophthalmic & Orbital Associates | Pittsburgh | Pennsylvania | 15212 | — |
| Retina Consultants of Charleston | Charleston | South Carolina | 29414 | — |
| Black Hills Regional Eye Institute | Rapid City | South Dakota | 57701 | — |
| Neuro-Opthalmology of Texas | Houston | Texas | 77030 | — |
| Medical Center Ophthalmology Associates | San Antonio | Texas | 78240 | — |
| University of Utah Health Sciences Center | Salt Lake City | Utah | 84132 | — |
| University of Washington Medical Center | Seattle | Washington | 98104 | — |
| Swedish Neuroscience Institute | Seattle | Washington | 98122 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01131104, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 5, 2018 · Synced Oct 26, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01131104 live on ClinicalTrials.gov.