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Completed Phase 1 Interventional

PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors

ClinicalTrials.gov ID: NCT01158300

Public ClinicalTrials.gov record NCT01158300. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 21, 2026, 10:37 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase I and Pharmacokinetic Trial of PTC299 in Pediatric Patients With Refractory or Recurrent CNS Tumors

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

RATIONALE: PTC299 may stop the growth of tumor cells by blocking blood flow to the tumor. PURPOSE: This phase I trial is studying the side effects and the best dose of PTC299 in treating young patients with recurrent or refractory primary central nervous system tumors.

Study identification

NCT ID
NCT01158300
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Enrollment
28 participants

Conditions and interventions

Eligibility (public fields only)

Age range
3 Years to 21 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 2010 (Type not available)
Primary completion
Jan 2015 (Actual)
Completion
Jan 2015 (Actual)
Last update posted
May 4, 2015

2010 – 2015

United States locations

U.S. sites
8
U.S. states
7
U.S. cities
8
Facility City State ZIP Site status
UCSF Cancer Center and Cancer Research Institute San Francisco California 94143-0128 —
Children's National Medical Center Washington D.C. District of Columbia 20010-2970 —
Children's Memorial Hospital - Chicago Chicago Illinois 60614 —
Duke Comprehensive Cancer Center Durham North Carolina 27710 —
Children's Hospital of Philadelphia Philadelphia Pennsylvania 19104-4318 —
Children's Hospital of Pittsburgh Pittsburgh Pennsylvania 15213 —
St. Jude Children's Research Hospital Memphis Tennessee 38105 —
Texas Children's Cancer Center and Hematology Service at Texas Children's Hospital Houston Texas 77030-2399 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01158300, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 4, 2015 · Synced Oct 21, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT01158300 live on ClinicalTrials.gov.

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