Vorinostat in Treating Patients With Locally Advanced, Recurrent, or Metastatic Adenoid Cystic Carcinoma
Public ClinicalTrials.gov record NCT01175980. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2 Study of Suberoylanilide Hydroxamic Acid (SAHA) in Subjects With Locally Advanced, Recurrent or Metastatic Adenoid Cystic Carcinoma (ACC)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This phase II trial studies how well vorinostat works in treating patients with adenoid cystic carcinoma that has come back (recurrent) or that has spread from where it started to nearby tissue or lymph nodes (locally advanced) or has spread to other places in the body (metastatic). Vorinostat may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
Study identification
- NCT ID
- NCT01175980
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 30 participants
Conditions and interventions
Conditions
- Recurrent Oral Cavity Adenoid Cystic Carcinoma
- Recurrent Salivary Gland Carcinoma
- Salivary Gland Adenoid Cystic Carcinoma
- Stage III Major Salivary Gland Cancer AJCC v7
- Stage III Oral Cavity Adenoid Cystic Carcinoma AJCC v6 and v7
- Stage IVA Major Salivary Gland Cancer AJCC v7
- Stage IVA Oral Cavity Adenoid Cystic Carcinoma AJCC v6 and v7
- Stage IVB Major Salivary Gland Cancer AJCC v7
- Stage IVB Oral Cavity Adenoid Cystic Carcinoma AJCC v6 and v7
- Stage IVC Major Salivary Gland Cancer AJCC v7
- Stage IVC Oral Cavity Adenoid Cystic Carcinoma AJCC v6 and v7
- Tongue Carcinoma
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 5, 2010
- Primary completion
- Jun 7, 2018
- Completion
- Jul 31, 2018
- Last update posted
- Aug 2, 2020
2010 – 2018
United States locations
- U.S. sites
- 11
- U.S. states
- 6
- U.S. cities
- 9
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| City of Hope Comprehensive Cancer Center | Duarte | California | 91010 | — |
| City of Hope South Pasadena | South Pasadena | California | 91030 | — |
| Yale University | New Haven | Connecticut | 06520 | — |
| National Institutes of Health Clinical Center | Bethesda | Maryland | 20892 | — |
| Wayne State University/Karmanos Cancer Institute | Detroit | Michigan | 48201 | — |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | — |
| Case Comprehensive Cancer Center | Cleveland | Ohio | 44106-5065 | — |
| Case Western Reserve University | Cleveland | Ohio | 44106 | — |
| Cleveland Veterans Administration | Cleveland | Ohio | 44106 | — |
| Lake University Ireland Cancer Center | Mentor | Ohio | 44060 | — |
| Ireland Cancer Center at Firelands Regional Medical Center | Sandusky | Ohio | 44870 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01175980, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 2, 2020 · Synced Sep 5, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01175980 live on ClinicalTrials.gov.