A Study To Evaluate The Effects And Safety Of Treatment, Treatment Withdrawal, Followed By Re-Treatment With CP-690,550 In Subjects With Moderate To Severe Chronic Plaque Psoriasis
Public ClinicalTrials.gov record NCT01186744. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multi-Site, Randomized, Mixed-Blind, Parallel-Group Treatment Withdrawal And Re-Treatment Study Of The Efficacy And Safety Of 2 Oral Doses Of CP-690,550 In Subjects With Moderate To Severe Chronic Plaque Psoriasis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objectives of the study are to 1) compare the efficacy responses of CP 690,550 (5 mg BID and 10 mg BID) versus placebo following 24 weeks of CP 690,550 treatment and subsequent withdrawal of active treatment at various timepoints during the 16 week double blind active or placebo treatment period; 2) evaluate the regain of efficacy responses of CP 690,550 (5 mg BID and 10 mg BID) following 4 -16 weeks of CP 690,550 treatment withdrawal and subsequent re treatment; and 3) evaluate the safety and tolerability of CP 690,550 (5 mg BID and 10 mg BID) in subjects with moderate to severe chronic plaque psoriasis who are candidates for systemic therapy or phototherapy.
Study identification
- NCT ID
- NCT01186744
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 666 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 2010 (Type not available)
- Primary completion
- Jan 2013 (Actual)
- Completion
- Jan 2013 (Actual)
- Last update posted
- Dec 26, 2018
2010 – 2013
United States locations
- U.S. sites
- 50
- U.S. states
- 21
- U.S. cities
- 36
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Horizon Research Group, Inc. | Mobile | Alabama | 36608 | — |
| Radiant Research, Inc. | Tucson | Arizona | 85710 | — |
| Center for Dermatology Clinical Research, Inc. | Fremont | California | 94538 | — |
| Associates In Research, Inc. | Fresno | California | 93720 | — |
| Dermatology Research Associates | Los Angeles | California | 90045 | — |
| Expresscare Medical | Los Angeles | California | 90045 | — |
| Dermatology Specialists, Inc. | Oceanside | California | 92056 | — |
| University of California San Francisco | San Francisco | California | 94118 | — |
| Longmont Clinic, PC | Longmont | Colorado | 80501 | — |
| New England Research Associates, LLC | Trumbull | Connecticut | 06611 | — |
| Florida Academic Dermatology Center | Miami | Florida | 33136 | — |
| International Dermatology Research, Inc. | Miami | Florida | 33144 | — |
| Park Avenue Dermatology, PA | Orange Park | Florida | 32073 | — |
| Ameriderm Research | Ormond Beach | Florida | 32174 | — |
| Miami Research Associates | South Miami | Florida | 33143 | — |
| Altman Dermatology Associates | Arlington Heights | Illinois | 60005 | — |
| Springfield Clinic, LLP | Springfield | Illinois | 62703 | — |
| Springfield Clinic | Springfield | Illinois | 62703 | — |
| Deaconess Clinic Downtown | Evansville | Indiana | 47713 | — |
| DMIA | Louisville | Kentucky | 40207 | — |
| DermResearch, PLLC | Louisville | Kentucky | 40217 | — |
| Quest Diagnostics | Louisville | Kentucky | 40217 | — |
| Northeast Dermatology Associates | Beverly | Massachusetts | 01915 | — |
| ActivMed Practices and Research, Inc. | Haverhill | Massachusetts | 01830 | — |
| Michigan Center for Research Corporation dba Michigan Center for Skin Care Research | Clinton Township | Michigan | 48038 | — |
| Minnesota Clinical Study Center | Fridley | Minnesota | 55432 | — |
| Comprehensive Clinical Research | Berlin | New Jersey | 08009 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Dermatology Consulting Services | High Point | North Carolina | 27262 | — |
| Dermatology Associates | Wilmington | North Carolina | 28401 | — |
| New Hanover Medical Group, PA | Wilmington | North Carolina | 28401 | — |
| New Hanover Medical Research | Wilmington | North Carolina | 28401 | — |
| PMG Research of Wilmington LLC | Wilmington | North Carolina | 28401 | — |
| Piedmont Imaging | Winston-Salem | North Carolina | 27103 | — |
| Piedmont Medical Research | Winston-Salem | North Carolina | 27103 | — |
| Triad Dermatology, PA | Winston-Salem | North Carolina | 27103 | — |
| Jewish Hospital | Cincinnati | Ohio | 45236 | — |
| Radiant Research, Inc. | Cincinnati | Ohio | 45249 | — |
| University Hospitals Case Medical Center | Cleveland | Ohio | 44106 | — |
| Oregon Medical Research Center, PC | Portland | Oregon | 97223 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| Medical Research South, LLC | Charleston | South Carolina | 29407 | — |
| Office of Marta T. Hampton, MD | Charleston | South Carolina | 29407 | — |
| Dermatology & Laser Center of Charleston | Charleston | South Carolina | 29414 | — |
| Office of John Michael Humeniuk, MD | Greer | South Carolina | 29650 | — |
| Radiant Research, Inc. | Greer | South Carolina | 29651 | — |
| Dermatology Research Associates | Nashville | Tennessee | 37203 | — |
| Office of Stephen Miller, MD, PA | San Antonio | Texas | 78229 | — |
| Center for Clinical Studies | Webster | Texas | 77598 | — |
| Mountain State Clinical Research | Clarksburg | West Virginia | 26301 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 37 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01186744, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 26, 2018 · Synced Oct 24, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01186744 live on ClinicalTrials.gov.