TRINOVA-1: A Study of AMG 386 or Placebo, in Combination With Weekly Paclitaxel Chemotherapy, as Treatment for Ovarian Cancer, Primary Peritoneal Cancer and Fallopian Tube Cancer
Public ClinicalTrials.gov record NCT01204749. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Blind Trial of Weekly Paclitaxel Plus AMG 386 or Placebo in Women With Recurrent Partially Platinum Sensitive or Resistant Epithelial Ovarian, Primary Peritoneal or Fallopian Tube Cancers
Study identification
- NCT ID
- NCT01204749
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Amgen
- Industry
- Enrollment
- 919 participants
Conditions and interventions
Interventions
- AMG 386 Drug
- AMG 386 Placebo Drug
- Paclitaxel Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 31, 2010
- Primary completion
- Feb 28, 2013
- Completion
- Nov 30, 2016
- Last update posted
- Dec 14, 2016
2010 – 2016
United States locations
- U.S. sites
- 35
- U.S. states
- 21
- U.S. cities
- 29
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Phoenix | Arizona | 85013 | — |
| Research Site | Los Angeles | California | 90048 | — |
| Research Site | San Diego | California | 92121 | — |
| Research Site | Stanford | California | 94305 | — |
| Research Site | Englewood | Colorado | 80113 | — |
| Research Site | Danbury | Connecticut | 06810 | — |
| Research Site | New Haven | Connecticut | 06520 | — |
| Research Site | Hollywood | Florida | 33021 | — |
| Research Site | Orlando | Florida | 32806 | — |
| Research Site | Honolulu | Hawaii | 96819 | — |
| Research Site | Honolulu | Hawaii | 96826 | — |
| Research Site | Boise | Idaho | 83712 | — |
| Research Site | Peoria | Illinois | 61615 | — |
| Research Site | Skokie | Illinois | 60076 | — |
| Research Site | Metairie | Louisiana | 70006 | — |
| Research Site | Baltimore | Maryland | 21201 | — |
| Research Site | Baltimore | Maryland | 21237 | — |
| Research Site | Boston | Massachusetts | 02114 | — |
| Research Site | Boston | Massachusetts | 02118 | — |
| Research Site | Lebanon | New Hampshire | 03756 | — |
| Research Site | Hackensack | New Jersey | 07601 | — |
| Research Site | Brightwaters | New York | 11718 | — |
| Research Site | New York | New York | 10029 | — |
| Research Site | New York | New York | 10032 | — |
| Research Site | Charlotte | North Carolina | 28203 | — |
| Research Site | Charlotte | North Carolina | 28204 | — |
| Research Site | Winston-Salem | North Carolina | 27103 | — |
| Research Site | Abington | Pennsylvania | 19001 | — |
| Research Site | Chattanooga | Tennessee | 37403 | — |
| Research Site | Houston | Texas | 77030 | — |
| Research Site | San Antonio | Texas | 78229 | — |
| Research Site | Ogden | Utah | 84403 | — |
| Research Site | Tacoma | Washington | 98405 | — |
| Research Site | Milwaukee | Wisconsin | 53215 | — |
| Research Site | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 190 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01204749, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 14, 2016 · Synced May 11, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01204749 live on ClinicalTrials.gov.