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Completed No phase listed Observational

Observational Study of Surgical Treatment of Necrotizing Enterocolotis

ClinicalTrials.gov ID: NCT01223261

Public ClinicalTrials.gov record NCT01223261. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 4, 2026, 9:54 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Observational Study of Surgical Treatment of Necrotizing Enterocolotis or Isolated Intestinal Perforation

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purposes of this study were: 1) to compare mortality and postoperative morbidities in extremely low birth weight (ELBW) infants who underwent initial laparotomy or drainage for necrotizing enterocolitis (NEC) or isolated intestinal perforation (IP); 2) to determine the ability to distinguish NEC from IP preoperatively and the importance of this distinction on outcome measures; and 3) to evaluate the association between extent of intestinal disease determined at operation and outcome measures. All ELBW infants born at participating NRN centers were screened for the presence of NEC or IP that was thought by the pediatric surgeon and neonatologist to require surgical intervention. Data were collected enrolled infants, including: intraoperative findings recorded by the surgeon and specific post-operative complications. Neurodevelopmental examinations were conducted on surviving infants at 18-22 months corrected age.

Study identification

NCT ID
NCT01223261
Recruitment status
Completed
Study type
Observational
Phase
Not listed
Enrollment
156 participants

Conditions and interventions

Eligibility (public fields only)

Age range
Up to 6 Weeks
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 28, 2001
Primary completion
Aug 31, 2002
Completion
Feb 29, 2004
Last update posted
Mar 21, 2019

2001 – 2004

United States locations

U.S. sites
17
U.S. states
12
U.S. cities
16
Facility City State ZIP Site status
University of Alabama at Birmingham Birmingham Alabama 35233
Stanford University Palo Alto California 94304
University of California at San Diego San Diego California 92103-8774
Yale University New Haven Connecticut 06504
University of Miami Miami Florida 33136
Emory University Atlanta Georgia 30303
Indiana University Indianapolis Indiana 46202
Wayne State University Detroit Michigan 48201
University of Rochester Rochester New York 14642
Wake Forest University Charlotte North Carolina 27157
RTI International Durham North Carolina 27705
Duke University Durham North Carolina 27710
Cincinnati Children's Medical Center Cincinnati Ohio 45267
Case Western Reserve University, Rainbow Babies and Children's Hospital Cleveland Ohio 44106
Brown University, Women & Infants Hospital of Rhode Island Providence Rhode Island 02905
University of Texas Southwestern Medical Center at Dallas Dallas Texas 75235
University of Texas Health Science Center at Houston Houston Texas 77030

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01223261, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 21, 2019 · Synced Sep 4, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01223261 live on ClinicalTrials.gov.

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