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Completed Phase 2 Interventional Results available

Avoiding the Hippocampus During Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases

ClinicalTrials.gov ID: NCT01227954

Public ClinicalTrials.gov record NCT01227954. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 29, 2026, 8:50 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase II Trial of Hippocampal Avoidance During Whole Brain Radiotherapy for Brain Metastases

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

RATIONALE: Radiation therapy uses high energy x-rays to kill tumor cells. PURPOSE: This phase II trial is studying how well avoiding the hippocampus during whole-brain radiation therapy works in treating patients with brain metastases.

Study identification

NCT ID
NCT01227954
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Enrollment
113 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 120 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 2011 (Type not available)
Primary completion
May 2013 (Actual)
Completion
Dec 2016 (Actual)
Last update posted
Sep 27, 2017

2011 – 2016

United States locations

U.S. sites
60
U.S. states
27
U.S. cities
54
Facility City State ZIP Site status
UAB Comprehensive Cancer Center Birmingham Alabama 35294 —
Arizona Center for Cancer Care - Peoria Peoria Arizona 85381 —
Mayo Clinic Scottsdale Scottsdale Arizona 85259-5499 —
Arizona Oncology - Tucson Tucson Arizona 85704 —
Arizona Cancer Center at University of Arizona Health Sciences Center Tucson Arizona 85724-5024 —
Veterans Affairs Medical Center - Long Beach Long Beach California 90822 —
Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center Los Angeles California 90048 —
Radiological Associates of Sacramento Medical Group, Incorporated Sacramento California 95815 —
University of California Davis Cancer Center Sacramento California 95817 —
CCOP - Christiana Care Health Services Newark Delaware 19713 —
Baptist Cancer Institute - Jacksonville Jacksonville Florida 32207 —
University of Miami Sylvester Comprehensive Cancer Center - Miami Miami Florida 33136 —
Baptist-South Miami Regional Cancer Program Miami Florida 33176 —
Florida Cancer Center - Palatka Palatka Florida 32177 —
Piedmont Hospital Atlanta Georgia 30309 —
Rush University Medical Center Chicago Illinois 60612 —
OSF St. Francis Medical Center Peoria Illinois 61637 —
Center for Cancer Care at Goshen General Hospital Goshen Indiana 46526 —
Indiana University Melvin and Bren Simon Cancer Center Indianapolis Indiana 46202-5289 —
Methodist Cancer Center at Methodist Hospital Indianapolis Indiana 46202 —
Greenebaum Cancer Center at University of Maryland Medical Center Baltimore Maryland 21201 —
NSMC Cancer Center - Peabody Danvers Massachusetts 01923 —
Barbara Ann Karmanos Cancer Institute Detroit Michigan 48201-1379 —
Mayo Clinic Cancer Center Rochester Minnesota 55905 —
Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis St Louis Missouri 63110 —
Billings Clinic - Downtown Billings Montana 59107-7000 —
Nebraska Medical Center Omaha Nebraska 68198 —
St. Barnabas Medical Center Cancer Center Livingston New Jersey 07039 —
New York Oncology Hematology, PC at Albany Regional Cancer Care Albany New York 12206 —
Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill Chapel Hill North Carolina 27599-7295 —
Summa Center for Cancer Care at Akron City Hospital Akron Ohio 44309-2090 —
Adena Regional Medical Center Chillicothe Ohio 45601 —
Case Comprehensive Cancer Center Cleveland Ohio 44106-5065 —
Cleveland Clinic Taussig Cancer Center Cleveland Ohio 44195 —
Arthur G. James Cancer Hospital and Richard J. Solove Research Institute at Ohio State University Comprehensive Cancer Center Columbus Ohio 43210-1240 —
Southwest General Health Center Middleburg Heights Ohio 44130 —
Oklahoma University Cancer Institute Oklahoma City Oklahoma 73104 —
Willamette Valley Cancer Center - Eugene Eugene Oregon 97401 —
Providence Cancer Center at Providence Portland Medical Center Portland Oregon 97213-2967 —
Rosenfeld Cancer Center at Abington Memorial Hospital Abington Pennsylvania 19001 —
Bryn Mawr Hospital Bryn Mawr Pennsylvania 19010 —
Regional Cancer Center - Erie Erie Pennsylvania 16505 —
Adams Cancer Center Gettysburg Pennsylvania 17325 —
Penn State Hershey Cancer Institute at Milton S. Hershey Medical Center Hershey Pennsylvania 17033-0850 —
Kimmel Cancer Center at Thomas Jefferson University - Philadelphia Philadelphia Pennsylvania 19107-5541 —
Lankenau Cancer Center at Lankenau Hospital Wynnewood Pennsylvania 19096 —
York Cancer Center at Apple Hill Medical Center York Pennsylvania 17405 —
Rapid City Regional Hospital Rapid City South Dakota 57701 —
Texas Oncology, PA at Harris Center HEB Bedford Texas 76022 —
Klabzuba Cancer Center at Harris Methodist Fort Worth Hospital Fort Worth Texas 76104 —
Memorial Hermann Hospital - Memorial City Houston Texas 77024 —
M. D. Anderson Cancer Center at University of Texas Houston Texas 77030-4009 —
Texas Oncology, PA at Texas Oncology Cancer Center Sugar Land Sugar Land Texas 77479 —
Jon and Karen Huntsman Cancer Center at Intermountain Medical Center Murray Utah 84157 —
Val and Ann Browning Cancer Center at McKay-Dee Hospital Center Ogden Utah 84403 —
Huntsman Cancer Institute at University of Utah Salt Lake City Utah 84112 —
University of Virginia Cancer Center Charlottesville Virginia 22908 —
Virginia Commonwealth University Massey Cancer Center Richmond Virginia 23298-0037 —
CCOP - Virginia Mason Research Center Seattle Washington 98101 —
Cancer Care Northwest - Spokane South Spokane Washington 99202 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01227954, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 27, 2017 · Synced Oct 29, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT01227954 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →