ClinicalTrials.gov record
Completed Phase 2 Interventional Results available

Avoiding the Hippocampus During Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases

ClinicalTrials.gov ID: NCT01227954

Public ClinicalTrials.gov record NCT01227954. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 12, 2026, 3:13 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase II Trial of Hippocampal Avoidance During Whole Brain Radiotherapy for Brain Metastases

Study identification

NCT ID
NCT01227954
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Radiation Therapy Oncology Group
Network
Enrollment
113 participants

Conditions and interventions

Interventions

  • intensity-modulated radiation therapy Radiation

Radiation

Eligibility (public fields only)

Age range
18 Years to 120 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 28, 2011
Primary completion
Apr 30, 2013
Completion
Nov 30, 2016
Last update posted
Sep 26, 2017

2011 – 2016

United States locations

U.S. sites
60
U.S. states
27
U.S. cities
54
Facility City State ZIP Site status
UAB Comprehensive Cancer Center Birmingham Alabama 35294
Arizona Center for Cancer Care - Peoria Peoria Arizona 85381
Mayo Clinic Scottsdale Scottsdale Arizona 85259-5499
Arizona Oncology - Tucson Tucson Arizona 85704
Arizona Cancer Center at University of Arizona Health Sciences Center Tucson Arizona 85724-5024
Veterans Affairs Medical Center - Long Beach Long Beach California 90822
Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center Los Angeles California 90048
Radiological Associates of Sacramento Medical Group, Incorporated Sacramento California 95815
University of California Davis Cancer Center Sacramento California 95817
CCOP - Christiana Care Health Services Newark Delaware 19713
Baptist Cancer Institute - Jacksonville Jacksonville Florida 32207
University of Miami Sylvester Comprehensive Cancer Center - Miami Miami Florida 33136
Baptist-South Miami Regional Cancer Program Miami Florida 33176
Florida Cancer Center - Palatka Palatka Florida 32177
Piedmont Hospital Atlanta Georgia 30309
Rush University Medical Center Chicago Illinois 60612
OSF St. Francis Medical Center Peoria Illinois 61637
Center for Cancer Care at Goshen General Hospital Goshen Indiana 46526
Indiana University Melvin and Bren Simon Cancer Center Indianapolis Indiana 46202-5289
Methodist Cancer Center at Methodist Hospital Indianapolis Indiana 46202
Greenebaum Cancer Center at University of Maryland Medical Center Baltimore Maryland 21201
NSMC Cancer Center - Peabody Danvers Massachusetts 01923
Barbara Ann Karmanos Cancer Institute Detroit Michigan 48201-1379
Mayo Clinic Cancer Center Rochester Minnesota 55905
Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis St Louis Missouri 63110
Billings Clinic - Downtown Billings Montana 59107-7000
Nebraska Medical Center Omaha Nebraska 68198
St. Barnabas Medical Center Cancer Center Livingston New Jersey 07039
New York Oncology Hematology, PC at Albany Regional Cancer Care Albany New York 12206
Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill Chapel Hill North Carolina 27599-7295
Summa Center for Cancer Care at Akron City Hospital Akron Ohio 44309-2090
Adena Regional Medical Center Chillicothe Ohio 45601
Case Comprehensive Cancer Center Cleveland Ohio 44106-5065
Cleveland Clinic Taussig Cancer Center Cleveland Ohio 44195
Arthur G. James Cancer Hospital and Richard J. Solove Research Institute at Ohio State University Comprehensive Cancer Center Columbus Ohio 43210-1240
Southwest General Health Center Middleburg Heights Ohio 44130
Oklahoma University Cancer Institute Oklahoma City Oklahoma 73104
Willamette Valley Cancer Center - Eugene Eugene Oregon 97401
Providence Cancer Center at Providence Portland Medical Center Portland Oregon 97213-2967
Rosenfeld Cancer Center at Abington Memorial Hospital Abington Pennsylvania 19001
Bryn Mawr Hospital Bryn Mawr Pennsylvania 19010
Regional Cancer Center - Erie Erie Pennsylvania 16505
Adams Cancer Center Gettysburg Pennsylvania 17325
Penn State Hershey Cancer Institute at Milton S. Hershey Medical Center Hershey Pennsylvania 17033-0850
Kimmel Cancer Center at Thomas Jefferson University - Philadelphia Philadelphia Pennsylvania 19107-5541
Lankenau Cancer Center at Lankenau Hospital Wynnewood Pennsylvania 19096
York Cancer Center at Apple Hill Medical Center York Pennsylvania 17405
Rapid City Regional Hospital Rapid City South Dakota 57701
Texas Oncology, PA at Harris Center HEB Bedford Texas 76022
Klabzuba Cancer Center at Harris Methodist Fort Worth Hospital Fort Worth Texas 76104
Memorial Hermann Hospital - Memorial City Houston Texas 77024
M. D. Anderson Cancer Center at University of Texas Houston Texas 77030-4009
Texas Oncology, PA at Texas Oncology Cancer Center Sugar Land Sugar Land Texas 77479
Jon and Karen Huntsman Cancer Center at Intermountain Medical Center Murray Utah 84157
Val and Ann Browning Cancer Center at McKay-Dee Hospital Center Ogden Utah 84403
Huntsman Cancer Institute at University of Utah Salt Lake City Utah 84112
University of Virginia Cancer Center Charlottesville Virginia 22908
Virginia Commonwealth University Massey Cancer Center Richmond Virginia 23298-0037
CCOP - Virginia Mason Research Center Seattle Washington 98101
Cancer Care Northwest - Spokane South Spokane Washington 99202

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01227954, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 26, 2017 · Synced May 12, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01227954 live on ClinicalTrials.gov.

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