Safety and Tolerability Study of ISIS EIF4E Rx in Combination With Carboplatin and Paclitaxel
Public ClinicalTrials.gov record NCT01234038. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1b/2 Study of Carboplatin-Paclitaxel, With or Without ISIS 183750 (an eIF4E Inhibitor), in Patients With Stage IV Non-Small Cell Lung Cancer
Study identification
- NCT ID
- NCT01234038
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- Ionis Pharmaceuticals, Inc.
- Industry
- Enrollment
- 116 participants
Conditions and interventions
Conditions
Interventions
- Carboplatin Drug
- ISIS EIF4E Rx Drug
- Paclitaxel Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 31, 2010
- Primary completion
- Sep 30, 2012
- Completion
- Dec 31, 2012
- Last update posted
- Jun 26, 2018
2010 – 2013
United States locations
- U.S. sites
- 10
- U.S. states
- 7
- U.S. cities
- 9
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Achieve Clinical Research | Birmingham | Alabama | 35216 | — |
| Highlands Oncology Group | Fayetteville | Arkansas | 72703 | — |
| Genesis Cancer Center | Hot Springs | Arkansas | 71913 | — |
| Little Rock Cancer Clinic | Little Rock | Arkansas | 72205 | — |
| Kenmar Research Institute | Los Angeles | California | 90057 | — |
| Joliet Hematology Oncology Associates | Joliet | Illinois | 60435 | — |
| University of Louisville - James Graham Brown Cancer Center | Louisville | Kentucky | 40202 | — |
| Jewish Hospital & St. Mary's Healthcare | Louisville | Kentucky | 40245 | — |
| Gabrail Cancer Center | Canton | Ohio | 44718 | — |
| Cancer Therapy and Research Center, University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78229 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 19 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01234038, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 26, 2018 · Synced Apr 29, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01234038 live on ClinicalTrials.gov.