Safety of Heparin in Patients With Septic Shock

ClinicalTrials.gov ID: NCT01234285

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Official title

Safety of Heparin Anticoagulation for Prevention of Death in Patients With Septic Shock.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Sepsis is a syndrome comprised of a systemic inflammatory response, signs of tissue hypoperfusion, and organ in the setting of presumed infection. Heparin, in addition to being an anticoagulant, is also a well-known antiinflammatory. The investigators believe that unfractionated heparin has the potential to save the lives of septic patients at a drastically reduced cost. This is a dose escalation study to determine the safety of increasing levels of heparin in this patient population; compare markers of anticoagulation and inflammation between treatment groups; and compare clinical outcomes between groups.

Study identification

NCT ID: NCT01234285
Recruitment status: Withdrawn
Study type: Interventional
Phase: Phase 2
Lead sponsor: University of Colorado, Denver; Other
Enrollment: Not listed

Conditions and interventions

Conditions

Sepsis

Interventions

heparin Drug

Drug

Eligibility (public fields only)

Age range: 18 Years to 90 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Dec 2010 (Type not available)
Primary completion: Apr 2013 (Estimated)
Completion: Oct 2013 (Estimated)
Last update posted: May 20, 2014

2010 – 2013

United States locations

U.S. sites: 1
U.S. states: 1
U.S. cities: 1

Facility	City	State	ZIP	Site status
University of Colorado Hospital	Aurora	Colorado	80045	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT01234285, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted May 20, 2014 · Synced Nov 12, 2026