Comparison of Pixantrone + Rituximab With Gemcitabine + Rituximab in Patients With Aggressive B-cell Non-Hodgkin Lymphoma or Follicular Grade 3 Lymphoma Who Have Relapsed After Therapy and Are Not Eligible for Stem Cell Transplant
Public ClinicalTrials.gov record NCT01321541. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized Multicenter Study Comparing Pixantrone + Rituximab With Gemcitabine + Rituximab in Patients With Aggressive B-cell Non-Hodgkin Lymphoma Who Have Relapsed After Therapy With CHOP-R or an Equivalent Regimen and Are Ineligible for Stem Cell Transplant
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the efficacy of Pixantrone + Rituximab compared to Gemcitabine + Rituximab in patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL), or follicular grade 3 lymphoma.
Study identification
- NCT ID
- NCT01321541
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 312 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 20, 2011 (Actual)
- Primary completion
- Jun 28, 2018 (Actual)
- Completion
- Sep 14, 2018 (Actual)
- Last update posted
- Nov 19, 2021
2011 – 2018
United States locations
- U.S. sites
- 51
- U.S. states
- 23
- U.S. cities
- 42
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Clinical Research Center | Tucson | Arizona | 85715 | — |
| Arizona Oncology Associates | Tucson | Arizona | 85745 | — |
| Highlands Oncology Group | Bentonville | Arkansas | 72712 | — |
| Highlands Oncology Group | Fayetteville | Arkansas | 72703 | — |
| Rocky Mountain Cancer Centers | Aurora | Colorado | 80012 | — |
| Rocky Mountain Cancer Centers | Boulder | Colorado | 80303 | — |
| Rocky Mountain Cancer Centers | Denver | Colorado | 80218 | — |
| George Washington University Department of Medicine | Washington D.C. | District of Columbia | 20037 | — |
| Integrated Community Oncology Network-St. Vincent's | Jacksonville | Florida | 32204 | — |
| Integrated Community Oncology Network-Southside | Jacksonville | Florida | 32207 | — |
| Integrated Community Oncology Network | Orange Park | Florida | 32073 | — |
| Carle Physician Group | Danville | Illinois | 61832 | — |
| Cancer Care Specialists of Central Illinois | Decatur | Illinois | 62526 | — |
| Crossroads Cancer Center | Effingham | Illinois | 62401 | — |
| Carle Foundation Physician Services | Mattoon | Illinois | 61938 | — |
| Carle Cancer Center | Urbana | Illinois | 61801 | — |
| Cancer Center of Kansas | Wichita | Kansas | 67208 | — |
| Cancer Center of Kansas | Wichita | Kansas | 67215 | — |
| Baptist Hospital East | Louisville | Kentucky | 40207 | — |
| Harry and Jeanette Weinberg Cancer Institute at Franklin Square | Baltimore | Maryland | 21237 | — |
| Center for Cancer and Blood Disorders, PC | Bethesda | Maryland | 20817 | — |
| Cancer & Hematology Center of Western Michigan | Grand Rapids | Michigan | 49450 | — |
| Metro Minnesota CCOP-Unity Hospital | Fridley | Minnesota | 55432 | — |
| Metro Minnesota CCOP-St. Johns | Maplewood | Minnesota | 55109 | — |
| Metro Minnesota Community Clinical Oncology Program | Saint Louis Park | Minnesota | 55416 | — |
| Metro Minnesota Community Clinical Oncology Program | Saint Louis Park | Minnesota | 55426 | — |
| Metro Minnesota CCOP-Regions Hospital | Saint Paul | Minnesota | 55101 | — |
| Missouri Cancer Associates | Columbia | Missouri | 65201 | — |
| Nebraska Hematology-Oncology, PC | Lincoln | Nebraska | 68506 | — |
| Hematology-Oncology Associates of Northern New Jersey | Morristown | New Jersey | 07962 | — |
| North Shore Hematology/Oncology Associates | East Setauket | New York | 11733 | — |
| Gabrail Cancer Center | Canton | Ohio | 44718 | — |
| Gabrail Cancer Center | Dover | Ohio | 44622 | — |
| Toledo Clinical Cancer Center | Toledo | Ohio | 43617 | — |
| Mercy Cancer Center at St. Anne's | Toledo | Ohio | 43623 | — |
| Toledo Clinic Cancer Center-Toledo | Toledo | Ohio | 43623 | — |
| Northwest Cancer Specialists, PC | Portland | Oregon | 97213 | — |
| Northwest Cancer Specialists, PC | Portland | Oregon | 97225 | — |
| Northwest Cancer Specialists, PC | Tualatin | Oregon | 97062 | — |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | — |
| Upstate Oncology Associates | Greenville | South Carolina | 29615 | — |
| South Carolina Cancer Specialists | Hardeeville | South Carolina | 29927 | — |
| South Carolina Cancer Specialists | Hilton Head Island | South Carolina | 29926 | — |
| Joe Arrington Cancer Research and Treatment Center | Lubbock | Texas | 79410 | — |
| Cancer Care Centers of South Texas-HOAST | New Braunfels | Texas | 78130 | — |
| Cancer Care Centers of South Texas-HOAST | San Antonio | Texas | 78229 | — |
| Blue Ridge Cancer Care | Roanoke | Virginia | 24014 | — |
| Northwest Cancer Specialists, PC | Vancouver | Washington | 98684 | — |
| Northwest Cancer Specialists, PC | Vancouver | Washington | 98686 | — |
| Saint Vincent Hospital Green Bay Oncology | Green Bay | Wisconsin | 54301 | — |
| Green Bay Oncology-St. Mary's Hospital MC | Green Bay | Wisconsin | 54303 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 80 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01321541, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 19, 2021 · Synced Oct 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01321541 live on ClinicalTrials.gov.