Denosumab Compared to Zoledronic Acid in the Treatment of Bone Disease in Patients With Multiple Myeloma
Public ClinicalTrials.gov record NCT01345019. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Multicenter Study of Denosumab Compared With Zoledronic Acid in the Treatment of Bone Disease in Subjects With Newly Diagnosed Multiple Myeloma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine if denosumab is non-inferior to zoledronic acid in the treatment of bone disease from multiple myeloma.
Study identification
- NCT ID
- NCT01345019
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,718 participants
Conditions and interventions
Conditions
Interventions
- Denosumab Drug
- Zoledronic acid Drug
- Placebo to Denosumab Drug
- Placebo to zoledronic acid Drug
- Denosumab (for the open-label treatment phase) Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 17, 2012 (Actual)
- Primary completion
- Jul 19, 2016 (Actual)
- Completion
- Mar 29, 2019 (Actual)
- Last update posted
- Nov 8, 2022
2012 – 2019
United States locations
- U.S. sites
- 79
- U.S. states
- 36
- U.S. cities
- 70
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Tucson | Arizona | 85704 | — |
| Research Site | Fayetteville | Arkansas | 72703 | — |
| Research Site | Anaheim | California | 92801 | — |
| Research Site | Campbell | California | 95008 | — |
| Research Site | Encinitas | California | 92024 | — |
| Research Site | Fresno | California | 93720 | — |
| Research Site | Pleasant Hill | California | 94523 | — |
| Research Site | Santa Barbara | California | 93105 | — |
| Research Site | Santa Maria | California | 93454 | — |
| Research Site | Stamford | Connecticut | 06902 | — |
| Research Site | Washington D.C. | District of Columbia | 20007 | — |
| Research Site | Washington D.C. | District of Columbia | 20010 | — |
| Research Site | Boynton Beach | Florida | 33426 | — |
| Research Site | Boynton Beach | Florida | 33435 | — |
| Research Site | Jacksonville | Florida | 32256 | — |
| Research Site | Columbus | Georgia | 31904 | — |
| Research Site | Savannah | Georgia | 31405 | — |
| Research Site | Chicago | Illinois | 60612 | — |
| Research Site | Joliet | Illinois | 60435 | — |
| Research Site | Maywood | Illinois | 60153 | — |
| Research Site | Niles | Illinois | 60714 | — |
| Research Site | Skokie | Illinois | 60076 | — |
| Research Site | Skokie | Illinois | 60077 | — |
| Research Site | Anderson | Indiana | 46016 | — |
| Research Site | Fort Wayne | Indiana | 46845 | — |
| Research Site | Indianapolis | Indiana | 46202 | — |
| Research Site | Ames | Iowa | 50010 | — |
| Research Site | Iowa City | Iowa | 52242 | — |
| Research Site | Paducah | Kentucky | 42003 | — |
| Research Site | New Orleans | Louisiana | 70121 | — |
| Research Site | Scarborough | Maine | 04074 | — |
| Research Site | Baltimore | Maryland | 21204 | — |
| Research Site | Baltimore | Maryland | 21229 | — |
| Research Site | Baltimore | Maryland | 21237 | — |
| Research Site | Bethesda | Maryland | 20817 | — |
| Research Site | Westminster | Maryland | 21157 | — |
| Research Site | Boston | Massachusetts | 02114 | — |
| Research Site | Boston | Massachusetts | 02215 | — |
| Research Site | Danvers | Massachusetts | 01923 | — |
| Research Site | Fairhaven | Massachusetts | 02719 | — |
| Research Site | Detroit | Michigan | 48201 | — |
| Research Site | Lansing | Michigan | 48910 | — |
| Research Site | Jackson | Mississippi | 39216 | — |
| Research Site | Springfield | Missouri | 65806 | — |
| Research Site | Billings | Montana | 59101 | — |
| Research Site | Lincoln | Nebraska | 68506 | — |
| Research Site | Omaha | Nebraska | 68198 | — |
| Research Site | North Las Vegas | Nevada | 89086 | — |
| Research Site | Hackensack | New Jersey | 07601 | — |
| Research Site | Lake Success | New York | 11042 | — |
| Research Site | New York | New York | 10021 | — |
| Research Site | Rochester | New York | 14621 | — |
| Research Site | Fayetteville | North Carolina | 28304 | — |
| Research Site | Goldsboro | North Carolina | 27534 | — |
| Research Site | High Point | North Carolina | 27262 | — |
| Research Site | Bismarck | North Dakota | 58501 | — |
| Research Site | Oklahoma City | Oklahoma | 73120-8345 | — |
| Research Site | Hershey | Pennsylvania | 17033 | — |
| Research Site | Philadelphia | Pennsylvania | 19106 | — |
| Research Site | Philadelphia | Pennsylvania | 19140 | — |
| Research Site | Philadelphia | Pennsylvania | 19141 | — |
| Research Site | West Reading | Pennsylvania | 19611 | — |
| Research Site | Charleston | South Carolina | 29406 | — |
| Research Site | Charleston | South Carolina | 29414 | — |
| Research Site | Greenville | South Carolina | 29615 | — |
| Research Site | Aberdeen | South Dakota | 57401 | — |
| Research Site | Rapid City | South Dakota | 57701 | — |
| Research Site | Sioux Falls | South Dakota | 57105 | — |
| Research Site | Watertown | South Dakota | 57201 | — |
| Research Site | Memphis | Tennessee | 38120 | — |
| Research Site | Houston | Texas | 77030 | — |
| Research Site | Lubbock | Texas | 79415 | — |
| Research Site | Salt Lake City | Utah | 84106 | — |
| Research Site | Christiansburg | Virginia | 24073 | — |
| Research Site | Spokane | Washington | 99208 | — |
| Research Site | Tacoma | Washington | 98405 | — |
| Research Site | Morgantown | West Virginia | 26506 | — |
| Research Site | Minocqua | Wisconsin | 54548 | — |
| Research Site | Wauwatosa | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 230 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01345019, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 8, 2022 · Synced Oct 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01345019 live on ClinicalTrials.gov.