ClinicalTrials.gov record

Completed Not applicable Interventional Accepts healthy volunteers Results available

Methemoglobin Levels in Generally Anesthetized Pediatric Dental Patients Receiving Local Anesthetics

ClinicalTrials.gov ID: NCT01402869

Public ClinicalTrials.gov record NCT01402869. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Sep 12, 2026, 3:59 AM EDT

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Official title

Methemoglobin Levels in Generally Anesthetized Pediatric Dental Patients Receiving Prilocaine Versus Lidocaine

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

To establish and compare maximum methemoglobin blood levels and times to maximum methemoglobin blood levels following the administration of the injectable local anesthetics prilocaine and lidocaine when used for dental treatment in pediatric patients under general anesthesia. Patients will be randomized into three equal study groups. Two of the study groups will receive local anesthetic and the third group will not. Methemoglobin blood levels will be non-invasively monitored and recorded throughout dental treatment for all groups using a Masimo Radical-7 Pulse Co-Oximeter device.

Study identification

NCT ID: NCT01402869
Recruitment status: Completed
Study type: Interventional
Phase: Not applicable
Lead sponsor: Loma Linda University; Other
Enrollment: 91 participants

Conditions and interventions

Conditions

Methemoglobinemia

Interventions

4% prilocaine plain Drug
2% Lidocaine with 1:100,000 epinephrine Drug

Drug

Eligibility (public fields only)

Age range: 3 Years to 5 Years
Sex: All
Healthy volunteers: Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Jul 31, 2011
Primary completion: Jun 30, 2012
Completion: Jun 30, 2012
Last update posted: Apr 24, 2014

2011 – 2012

United States locations

U.S. sites: 1
U.S. states: 1
U.S. cities: 1

Facility	City	State	ZIP	Site status
Loma Linda University School of Dentistry Koppel Special Care Dentistry Center	Loma Linda	California	92350	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT01402869, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 24, 2014 · Synced Sep 12, 2026

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The complete protocol, eligibility criteria, and contact information for NCT01402869 live on ClinicalTrials.gov.

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